Giant cell tumours of the mobile spine: characteristic imaging features and differential diagnosis

2014 ◽  
Vol 119 (9) ◽  
pp. 681-693 ◽  
Author(s):  
Ming-Jue Si ◽  
Chen-Guang Wang ◽  
Cheng-Sheng Wang ◽  
Lian-Jun Du ◽  
Xiao-Yi Ding ◽  
...  
2021 ◽  
pp. 219256822098228
Author(s):  
Bei Yuan ◽  
Lihua Zhang ◽  
Shaomin Yang ◽  
Hanqiang Ouyang ◽  
Songbo Han ◽  
...  

Study Design: Retrospective study. Objectives: Giant cell tumors (GCTs) of the mobile spine can be locally aggressive. This study described and classified the typical and atypical appearance of aggressive spinal GCTs according to imaging findings to help the imaging diagnosis, especially for patients with rapid neurological deficit that may require emergent surgery without biopsy. Methods: Computed tomography (CT) and magnetic resonance imaging (MRI) scans of patients diagnosed with aggressive spinal GCTs at single center were reviewed. Results: Overall, 101 patients with 100 CT images and 94 MR images were examined. All lesions were osteolytic with cortical destruction; 95 lesions showed epidural extension; 90 were centered in the vertebral body; 82 showed pathological fracture and/or collapse of the vertebral body; 78 had pseudotrabeculation on CT; 80 showed low-to-iso signal intensity or heterogeneous high-signal intensity with cystic areas on the T2-weighted images; 9 showed fluid–fluid level on T2-weighted images; and 61 patients showed marked enhancement on contrast-enhanced CT and/or MRI. Forty-one lesions (40.6%) had at least 1 atypical radiographic feature: 19 involved ≥2 segments; 11 were centered in the posterior neural arch; 10 had a paravertebral mass over 2 segments; 16 showed partial margin sclerosis with partial cortical destruction on CT scans; and 3 showed mineralization within the tumor on CT. Eighty-eight patients underwent CT-guided biopsy with a diagnostic accuracy rate of 94.3%. Conclusions: Spinal GCTs might appear more radiologically atypical, and about 40% of the lesions may have at least 1 atypical feature. CT-guided biopsies are recommended for definitive diagnosis.


Author(s):  
Daichi Hayashi ◽  
Ali Guermazi ◽  
Frank W. Roemer

Chapter 45 discusses imaging of erosive osteoarthritis (EOA), a severe phenotype of osteoarthritis (OA) characterized by erosions and superimposed synovitis, most typically seen in women in the interphalangeal (IP) joints of the hand. Radiography is the primary imaging modality used in the diagnosis of EOA. EOA is distinguished from non-EOA based on the presence of erosions on radiography. US and MRI can be useful in detecting erosions, joint effusion, and active synovitis that may precede radiographic changes. The most common differential diagnosis of EOA is psoriatic arthritis (PsA), which exhibits additional characteristic imaging features such as bony proliferations and periostitis.


2020 ◽  
Vol 22 (3) ◽  
pp. 319
Author(s):  
Christoph F. Dietrich ◽  
Wiem Douira-Khomsi ◽  
Hassen Gharbi ◽  
Malay Sharma ◽  
Xin Wu Cui ◽  
...  

Cystic echinococcosis (CE) or hydatidosis (hydatid cysts), is an infection with a wide spectrum of manifestations, from asymptomatic infection to fatal disease. Ultrasound (US) allows screening, diagnosis, differential diagnosis, treatment guidance and follow-up of CE under many circumstances. Hydatid cysts are predominantly observed in the liver but many other organs can be involved. As part of a series of publications, herewith we present a review describing the characteristic imaging features of the broad variety of organs which can be involved.


2019 ◽  
Vol 1 ◽  
pp. 114-116
Author(s):  
Catrin Wigley ◽  
Guy Morris ◽  
Scott Evans ◽  
Rajesh Botchu

Pretibial lesion can have a plethora of differential diagnosis. We report a case of extraosseous pretibial ganglion cyst which was referred to our orthopedic oncology service and described the imaging features.


2017 ◽  
Author(s):  
Stefano Boriani ◽  
Luca Boriani

2020 ◽  
Vol 49 (2) ◽  
pp. 20190202
Author(s):  
Zhendong Luo ◽  
Weiguo Chen ◽  
Xinping Shen ◽  
Genggeng Qin ◽  
Jianxiang Yuan ◽  
...  

Objective: This study aims to assess the CT and MRI features of head and neck osteosarcoma (HNO). Methods: 37 HNOs were identified, and the following imaging characteristics were reviewed on CT and MRI. Results: A total of 37 patients(age 41.5 ± 15.0 years old; 16 males, 21 females) were included in the study. Tumours occurred in the maxilla (16, 43.2%), mandible (8, 21.6%), skull base (6, 16.2%), calvarium (5, 13.5%), paranasal sinuses (1, 2.7%) and cervical soft tissue (1, 2.7%). 16 patients received radiotherapy for nasopharyngeal carcinoma. Three patients (8.1%) developed osteosarcomas related to a primary bone disease. 16 of the (43.2%) tumours demonstrated lytic density on CT scans, followed by 13 (35.1%) showing mixed density and 7 (18.9%) with sclerotic density. Matrix mineralization was present in 32 (86.5%). 3 out of 24 (12.5%) tumours showed lamellar periosteal reactions, 21 out of 24 (87.5%) showed spiculated periosteal reactions. 12 tumours showed low signal intensities on T1WI, with 16 having heterogeneous signal intensities. 10 tumours showed high signal intensities on T2WI, and 18 showed heterogeneous signal intensities. With contrast-enhanced images, 3 tumours showed homogeneous enhancement (2 osteoblastic and 1 giant cell-rich), 18 tumours showed heterogeneous enhancement (13 osteoblastic, 4 fibroblastic and 1 giant cell-rich), and 7 tumours showed peripheral enhancement (6 chondroblastic and 1 osteoblastic). These tumours were characterized by soft tissue masses with a diameter of 5.6 ± 1.8 cm. Conclusions: HNO is a rare condition and is commonly associated with previous radiation exposure. This study provides age, sex distribution, location, CT and MRI features of HNO.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Akira Masanori

AbstractOur understanding of the manifestations of pneumoconioses is evolving in recent years. Associations between novel exposures and diffuse interstitial lung disease have been newly recognized. In advanced asbestosis, two types of fibrosis are seen, probably related to dose of exposure, existence of pleural fibrosis, and the host factor status of the individual. In pneumoconiosis of predominant reticular type, nodular opacities are often seen in the early phase. The nodular pattern is centrilobular, although some in metal lung show perilymphatic distribution, mimicking sarcoidosis. High-resolution computed tomography enables a more comprehensive correlation between the pathologic findings and clinically relevant imaging findings. The clinician must understand the spectrum of characteristic imaging features related to both known dust exposures and to historically recent new dust exposures.


2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Annalisa Papa ◽  
Chiara Pozzessere ◽  
Francesco Cicone ◽  
Fabiola Rizzuto ◽  
Giuseppe Lucio Cascini

Abstract Coronavirus disease-19 (COVID-19) is only one of the many possible infectious and non-infectious diseases that may occur with similar imaging features in patients undergoing [18F]-fluorodeoxyglucose (18FDG) monitoring, particularly in the most fragile oncologic patients. We briefly summarise some key radiological elements of differential diagnosis of interstitial lung diseases which, in our opinion, could be extremely useful for physicians reporting 18FDG PET/CT scans, not only during the COVID-19 pandemic, but also for their normal routine activity.


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