Thermal ablation of liver metastases from colorectal cancer: radiofrequency, microwave and laser ablation therapies

2014 ◽  
Vol 119 (7) ◽  
pp. 451-461 ◽  
Author(s):  
Thomas J. Vogl ◽  
Parviz Farshid ◽  
Nagy N. N. Naguib ◽  
Abbas Darvishi ◽  
Babak Bazrafshan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Laser Ablation ◽  
Liver Metastases ◽  
Thermal Ablation

Laser Ablation of Liver Metastases from Colorectal Cancer with MR Thermometry: 5-Year Survival

2009 ◽  
Vol 20 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Ralf Puls ◽  
Soenke Langner ◽  
Christian Rosenberg ◽  
Katrin Hegenscheid ◽  
Jens Peter Kuehn ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Laser Ablation ◽  
Liver Metastases ◽  
Mr Thermometry

scholarly journals Prognosis of the combination therapy results in patients with synchronous metastases of colorectal cancer

2019 ◽  
Vol 4 (3) ◽  
pp. 60-64
Author(s):  
S. V Kozlov ◽  
O. I Kaganov ◽  
A. A Moryatov ◽  
A. M Kozlov ◽  
A. P Borisov
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastases ◽  
Cytoreductive Surgery ◽  
Thermal Ablation ◽  
Combined Treatment ◽  
Stage Iv ◽  
Radiofrequency Thermal Ablation ◽  
Mutational Status ◽  
Synchronous Metastases ◽  
Metastatic Liver

Objectives - to optimize the indications for radiofrequency thermal ablation in patients with synchronous multiple metastases of colorectal cancer to the liver on the basis of prognostic treatment results. Material and methods. The study group included 78 patients with colorectal cancer with synchronous multiple bilobar liver metastases, who have underwent combined treatment in the period of 2007- 2015, such as cytoreductive surgery removing the primary intestinal tumor in combination with RFA of metastases in the liver, followed by chemotherapy. Results. A computer program for preoperative risk assessment of disease progression was developed and introduced in clinical practice. It is based on the results of the analysis of the factors, predicting the risk of relapse during the first year after cytoreductive surgery with RFA of synchronous multiple CRC liver metastases. Conclusion. The index of metastatic liver damage (the product of the sum of the diameters of metastatic liver lesions by their number), the mutational status of the KRAS gene, CEA values are significant factors in predicting the progression of the disease, which can optimize indications for radiofrequency thermal ablation in the treatment of patients with stage IV CRC with synchronous metastases to the liver.

scholarly journals Microwave ablation in the treatment of liver tumors. A better tool or simply more power?

2020 ◽  
Vol 22 (4) ◽  
pp. 451
Author(s):  
Zeno Sparchez ◽  
Tudor Mocan ◽  
Pompilia Radu ◽  
Iuliana Nenu ◽  
Mihai Comsa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Liver Metastases ◽  
Intrahepatic Cholangiocarcinoma ◽  
Thermal Ablation ◽  
Microwave Ablation ◽  
Liver Tumors ◽  
Colorectal Cancer Liver Metastases ◽  
Clinical Scenarios

It has been a long time since tumor ablation was first tested in patients with liver cancer, especially hepatocellular carcinoma. Since than it has become a first line treatment modality for hepatocellular carcinoma. Over the years, the indications of thermal ablation have expanded to colorectal cancer liver metastases and intrahepatic cholangiocarcinoma as well. Together with the new indication for ablation, new ablation devices have been developed as well. Among them microwave ablation shows potential in replacing radiofrequency ablation as the preferred method of thermal ablation in liver cancer. The debate whether radiofrequency or microwave ablation should be the preferred method of treatment in patients with liver cancer remains open. The main purpose of this review is to offer some answers to the question: Microwave ablation in liver tumors: a better tool or simply more power? Various clinical scenarios will be analyzed including small, medium, and intermediate size hepatocellular carcinoma, colorectal cancer liver metastases and intrahepatic cholangiocarcinoma. Furthermore, the advantages, limitations, and technical considerations of MWA treatment will be provided also.

scholarly journals Local Control by Radiofrequency Thermal Ablation Increased Overall Survival in Patients With Refractory Liver Metastases of Colorectal Cancer

Medicine ◽  
2016 ◽  
Vol 95 (14) ◽  
pp. e3338 ◽  
Author(s):  
Po-Chih Yang ◽  
Been-Ren Lin ◽  
Yi-Chang Chen ◽  
Yu-Lin Lin ◽  
Hong-Shiee Lai ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Liver Metastases ◽  
Local Control ◽  
Thermal Ablation ◽  
Radiofrequency Thermal Ablation

scholarly journals Occlusion of the vein adjacent to colorectal cancer liver metastasis as a way to increase the radicality of percutaneous radiofrequency thermal ablation

2021 ◽  
pp. 57-63
Author(s):  
K. L. Murashko ◽  
A. M. Yurkovskiy
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Liver Metastases ◽  
Lower Incidence ◽  
Thermal Ablation ◽  
Heat Removal ◽  
Residual Tumor ◽  
Control Group ◽  
Colorectal Cancer Liver Metastasis ◽  
Radiofrequency Thermal Ablation

Objective. To evaluate the effectiveness of preoperative coagulation of the vein adjacent to a tumor nodule in sonographically-guided percutaneous radiofrequency thermal ablation of perivascular liver metastases of colorectal cancer.Materials and methods. To address the issue, we compared the results of sonographically-guided percutaneous radiofrequency thermal ablation of perivascular liver metastases of colorectal cancer in 27 patients (aged 60.5 (58; 68) years) without prior coagulation of the adjacent vein (control group) and 26 patients (62.0 (60; 74)) with prior coagulation of the adjacent vein (experimental group).Results. Lower incidence of residual tumor in the ablation area in the patients with prior coagulation of the adjacent vein (14.3 % vs. 29 % of the patients in the control group) and a higher relapse-free survival of such patients (65.2 % vs. 53.6 % and 55.6 % vs. 33.3 %) were reported as compared to the group without prior coagulation of the adjacent vein (after 6 and 12 months, respectively).Conclusion. Preoperative coagulation of the vein adjacent to colorectal cancer liver metastasis allows reducing the effect of heat removal from the RFA zone, thereby contributing to higher radicality of the treatment and resulting both in a lower incidence of residual tumor in the ablation zone and a higher relapse-free survivalof patients, notably without signifcant concomitant changes in the affected part of the liver (segment atrophy).

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