scholarly journals Magnetic resonance imaging findings in 11 cases of dedifferentiated endometrial carcinoma of the uterus

2021 ◽  
Author(s):  
Nao Kikkawa ◽  
Kimiteru Ito ◽  
Hiroshi Yoshida ◽  
Mayumi Kobayashi Kato ◽  
Yuko Kubo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endometrial Carcinoma ◽  
Low Grade ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Intratumoral Hemorrhage ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

Abstract Purpose We evaluated magnetic resonance imaging (MRI) findings of dedifferentiated endometrial carcinoma (DEC), comprising undifferentiated carcinoma and low-grade endometrioid carcinoma. Materials and methods We recruited 11 patients with pathologically proven DEC treated at our institute. We evaluated primary lesion size, location and signal intensity on MRI, and prognosis. MRI and pathological findings were compared in eight resected patients. Results Primary tumors ranged from 16 to 206 mm in diameter. DEC was located at the endometrium in 9 of the 11 patients; the remaining two patients showed diffuse involvement of the enlarged myometrium. These two patients with diffuse involvement type died within 4 months. Of the eight patients who underwent resection, seven had macroscopic intratumoral hemorrhage and six showed a high signal on T1-weighted images or low signal on T2-weighted images. Of the eight resected patients, four had tumor necrosis > 25% and tumor size > 5 cm. In these patients, necrosis appeared as nonenhanced areas on contrast-enhanced MRI. Conclusion MRI findings of DEC showed two patterns: mass-forming type and diffuse myometrial type with poor prognosis. Most patients with DEC had intratumoral hemorrhage, and large tumors (> 5 cm) had gross necrosis, which appeared as nonenhanced areas on contrast-enhanced MRI.

scholarly journals The Potentials and Role of Diffusion-Weighted Magnetic Resonance Imaging in Evaluating the Efficiency of Antitumor Treatment of Patients with Breast Liver Metastasis

2019 ◽  
Vol 100 (5) ◽  
pp. 286-292
Author(s):  
А. B. Lukiyanchenko ◽  
B. М. Medvedeva ◽  
E. S. Kolobanova ◽  
К. A. Romanova ◽  
S. S. Magamedova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Liver Metastasis ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Intravenous Contrast ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Abdominal Mri ◽  
Metastatic Process ◽  
Contrast Enhanced Mri

Objective. To compare the informative value of using dynamic magnetic resonance imaging (MRI) and diffusion-weighted MRI (DW-MRI) in patients with breast liver metastasis during chemotherapy.Material and methods. The investigation enrolled 30 patients with breast liver metastasis during their treatment. The results of standard intravenous contrast-enhanced abdominal MRI studies (by evaluating the liver in the arterial, venous, and delayed phases) were compared with those of DW-MRI with different B-factor values (50, 400 and 800 sec/mm2).Results. Comparison of the findings of initial studies prior to chemotherapy (those of only dynamic intravenous contrast-enhanced MRI and only DW-MRI) revealed a complete correspondence with the number of detected foci in 10 patients. Ten patients had a larger number of metastatic foci at DW-MRI than at intravenous contrast-enhanced MRI, in the aggregate by 44 foci more (of them 36 foci measured less than 1 cm). The remaining 10 of the 30 patients were found to have multiple, unquantifiable (more than 20–40) metastatic foci of various sizes (1–6 cm) at both intravenous contrast-enhanced MRI and DW-MRI. Nineteen of the 30 patients were followed up during their chemotherapy. Seven of the 19 patients showed a stabilized liver metastatic process that was similarly evidenced by both techniques. Eleven of the 19 patients were observed to have a progressive metastatic process that was reflected by the similar increase in the number and size of metastases in 5 of the 11 patients, as shown by both of the above techniques. In the remaining 6 of the 11 patients, the number of newly detected liver tumors proved to be larger at DW-MRI than at intravenous contrast-enhanced MRI. Both techniques showed that the last patient of the 19 cases had a decrease in the number of small liver metastases that maintained their sizes (less than 1 cm).Conclusion. DW-MRI has been shown to be much more effective in detecting metastases than conventional intravenous contrast-enhanced MRI, which necessitates the inclusion of this technique in standard abdominal MRI protocols for patients with liver metastasis.

scholarly journals Contrast-enhanced Magnetic Resonance Imaging in Pediatric Patients: Review and Recommendations for Current Practice

2013 ◽  
Vol 6 ◽  
pp. MRI.S12561 ◽  
Author(s):  
Ravi Bhargava ◽  
Gabriele Hahn ◽  
Wolfgang Hirsch ◽  
Myung-Joon Kim ◽  
Hans-Joachim Mentzel ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Medium ◽  
Best Practice ◽  
Imaging Modality ◽  
Published Data ◽  
Resonance Imaging ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Contrast Enhanced Mri

Magnetic resonance imaging (MRI), frequently with contrast enhancement, is the preferred imaging modality for many indications in children. Practice varies widely between centers, reflecting the rapid pace of change and the need for further research. Guideline changes, for example on contrast-medium choice, require continued practice reappraisal. This article reviews recent developments in pediatric contrast-enhanced MRI and offers recommendations on current best practice. Nine leading pediatric radiologists from internationally recognized radiology centers convened at a consensus meeting in Bordeaux, France, to discuss applications of contrast-enhanced MRI across a range of indications in children. Review of the literature indicated that few published data provide guidance on best practice in pediatric MRI. Discussion among the experts concluded that MRI is preferred over ionizing-radiation modalities for many indications, with advantages in safety and efficacy. Awareness of age-specific adaptations in MRI technique can optimize image quality. Gadolinium-based contrast media are recommended for enhancing imaging quality. The choice of most appropriate contrast medium should be based on criteria of safety, tolerability, and efficacy, characterized in age-specific clinical trials and personal experience.

scholarly journals Diagnostic accuracy of contrast enhanced MRI pelvis in differentiating indeterminate adnexal lesions into benign and malignant with histopathological correlation

2021 ◽  
Vol 10 (7) ◽  
pp. 846
Author(s):  
Sorath Murtaza ◽  
Junaid Iqbal ◽  
Saad Ahmed ◽  
Ashraf Amir Ali ◽  
Marya Hameed ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Tumor Size ◽  
Resonance Imaging ◽  
Histopathological Correlation ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Malignant Lesions ◽  
Contrast Enhanced Mri

Background: The objective of our study was to determine the diagnostic accuracy of contrast-enhanced magnetic resonance imaging pelvis in differentiating indeterminate adnexal lesions into benign and malignant, while considering histopathological examinations as the gold standard.Methods: A total 880 patients who underwent contrast enhanced MRI pelvis in our institute from January 2014 to June 2016 were prospectively analyzed.Results: A total of 880 women were included in this study, of which 782 (88.8%) were younger than 50 years and 98 (11.1%) were older than 50 years. Mean patient age was 56.7 years and mean tumor size was 4.38 cm. There were 648 (73.60%) patients who had a tumor size of >4 cm, and 337 (38.29%) of these tumors were found to be malignant. Furthermore, tumors smaller than 4 cm in size were observed in 232 (26.36%) of patients, of which tumors in 225 (25.56%) patients were benign.Conclusions: The diagnostic accuracy of contrast-enhanced MRI was found to be significantly high (79.65%) in differentiating indeterminate adnexal lesions into benign and malignant lesions.

scholarly journals Reliability of NI-RADS criteria in the interpretation of contrast-enhanced magnetic resonance imaging considering the potential role of diffusion-weighted imaging

2021 ◽  
Author(s):  
Fabian Henry Jürgen Elsholtz ◽  
Christoph Erxleben ◽  
Hans-Christian Bauknecht ◽  
Patrick Dinkelborg ◽  
Kilian Kreutzer ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Head And Neck ◽  
Diffusion Weighted Imaging ◽  
Primary Site ◽  
Resonance Imaging ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Interreader Agreement ◽  
Contrast Enhanced Mri

Abstract Objectives To assess inter- and intrareader agreement of the Neck Imaging Reporting and Data System (NI-RADS) used in contrast-enhanced magnetic resonance imaging (MRI) including analysis of diffusion-weighted imaging (DWI), which is currently not part of the NI-RADS criteria. Methods This retrospective study included anonymized surveillance contrast-enhanced MRI datasets of 104 patients treated for different head and neck cancers. Three radiologists experienced in head and neck imaging reported findings for the primary site and the neck using NI-RADS criteria in a first step and evaluated DWI sequences for the primary site in a second step. Thirty randomly selected imaging datasets were again presented to the readers. Kappa statistics and observed agreement (Ao) were calculated. Results Interreader agreement across all MRI datasets was moderate (κFleiss = 0.53) for NI-RADS categories assigned to the primary site, substantial for NI-RADS categories of the neck (κFleiss = 0.67), and almost perfect for DWI of the primary site (κFleiss = 0.83). Interreader agreement for the primary site was particularly low in cases of cancer recurrence (κFleiss = 0.35) and when categories 2a, 2b, and 3 were combined (κFleiss = 0.30). Intrareader agreement was considerably lower for NI-RADS categories of the primary site (range Ao = 53.3–70.0%) than for NI-RADS categories of the neck (range Ao = 83.3–90.0%) and DWI of the primary site (range Ao = 93.3–100.0%). Conclusion Interreader agreement of NI-RADS for reporting contrast-enhanced MRI findings is acceptable for the neck but limited for the primary site. Here, DWI has the potential to serve as a reliable additional criterion. Key Points • NI-RADS was originally designed for contrast-enhanced computed tomography with or without positron emission tomography but can also be used for contrast-enhanced magnetic resonance imaging alone. • Overall interreader agreement was acceptable for NI-RADS categories assigned to the neck but should be improved for the primary site, where it was inferior to DWI; similar tendencies were found for intrareader agreement. • DWI is currently no criterion of NI-RADS, but has shown potential to improve its reliability, especially for categories 2a, 2b, and 3 of the primary site.

Added Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Predicting Advanced Stage Disease in Patients With Endometrial Carcinoma

2009 ◽  
Vol 19 (1) ◽  
pp. 141-146 ◽  
Author(s):  
Evis Sala ◽  
Robin Crawford ◽  
Emma Senior ◽  
Ashley Shaw ◽  
Bryony Simcock ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endometrial Carcinoma ◽  
Myometrial Invasion ◽  
Added Value ◽  
Resonance Imaging ◽  
Dce Mri ◽  
3 Dimensional ◽  
Stage Disease ◽  
Contrast Enhanced

Aim:To assess the added value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting advanced stage disease in patients with endometrial carcinoma.Materials and Methods:Fifty patients with endometrial carcinoma underwent preoperative MRI assessment in a single gynecological cancer center during a 2-year period. Magnetic resonance imaging examinations included high-resolution sagittal, axial, and axial-oblique T2-weighted images (T2WI) of the pelvis, and axial T1-weighted images (T1WI) of the pelvis and upper abdomen followed by DCE-MRI using a multiphase 3-dimensional gradient refocused echo T1WI sequence. The T2W images were evaluated initially, and local and overall staging was assigned according to the FIGO classification. An identical scoring system was used to evaluate the combination of DCE-MRI and T2WI. The presence of potential pitfalls in the accurate assessment of depth of myometrial invasion (leiomyoma, adenomyosis, loss of junctional zone definition, polypoid tumor, poor tumor-to-myometrium contrast, and tumor extension to uterine cornu) was also recorded. Surgical histology constituted the standard of reference.Results:The depth of myometrial invasion was correctly determined in 78% (39/50) of the cases on T2WI alone, increasing to 92% (46/50) with the addition of DCE-MRI (95% confidence interval for improvement, 4.4%-23.6%, P = 0.016). The addition of DCE-MRI led to the correct detection of deep myometrial invasion in all cases. Tumor extension to uterine cornu was the only variable significantly associated (P = 0.014) with incorrect estimation of depth of myometrial invasion.Conclusions:The addition of multiphase 3-dimensional DCE-MRI to T2WI can effectively assess the depth of myometrial invasion in endometrial carcinoma and may be a useful tool to guide the surgical approach.

scholarly journals Magnetic resonance imaging of vulvar dermatofibrosarcoma protuberans – report of a case

2013 ◽  
Vol 47 (3) ◽  
pp. 244-246 ◽  
Author(s):  
Evrim Ozmen ◽  
Güven Güney ◽  
Oktay Algin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Dermatofibrosarcoma Protuberans ◽  
Lymph Node Involvement ◽  
Low Grade ◽  
Resonance Imaging ◽  
Mri Findings ◽  
First Case ◽  
Mri Features

Abstract Background. Dermatofibrosarcoma protuberans (DFSP) of the vulva is a rare low-grade soft tissue sarcoma. Magnetic resonance imaging (MRI) findings of vulvar DFSP were essentially unreported in the literature. Case report. We report a DFSP of vulva with its clinical, histological and MRI features. As far we know this is the first case of histologically confirmed vulvar DFSP presenting with MR images. The diagnosis of DFSP is usually made by histopathologic and clinical findings. Conclusions. MRI is useful both for the diagnosis of DFSP and following up the patients since it has high soft tissue resolution and no risk of radiation exposure. With MRI the relation to the adjacent anatomical structures, extension and depth of the tumour and possible lymph node involvement can also be demonstrated.

scholarly journals The Use of Endoscopic Ultrasonography and Other Imaging Modalities in the Preoperative Staging of Rectal Villous Tumours: A Case of Overstaging by Magnetic Resonance Imaging

2009 ◽  
Vol 23 (9) ◽  
pp. 639-641 ◽  
Author(s):  
Michelle Buresi ◽  
Iman Zandieh ◽  
Alexander G Nagy ◽  
Audrey Spielmann ◽  
William C Yee ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Villous Adenoma ◽  
Imaging Modality ◽  
Preoperative Staging ◽  
Muscularis Propria ◽  
Low Grade ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Meta Analyses

A case of a 60-year-old man with recurrent rectal villous adenoma is described. Preoperative staging with endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI) revealed very discordant results. EUS showed a tumour present in the mucosa with no submucosal invasion, while MRI revealed invasion of the muscularis propria consistent with an invasive stage T2 carcinoma. Based on the MRI findings, the patient underwent a low anterior resection of the tumour. The surgical pathology specimen revealed a villous adenoma with low-grade dysplasia but no carcinoma and no extension into the muscularis propria. The present case highlights the uncertainty that currently exists as to which imaging modality provides the greatest accuracy in the staging of rectal cancer and in guiding the type of surgical procedure performed. Two recent meta-analyses and a systematic review of the literature point to EUS as the imaging modality of choice for determining muscularis propria and perirectal tissue invasion, as well as nodal involvement.

scholarly journals TO EVALUATE THE ROLE OF MAGNETIC RESONANCE IMAGING (MRI) IN PELVIC MASSES IN FEMALE PATIENTS

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
G. Santhosh Kumar ◽  
Sawleha Arshi Khan ◽  
Disha Shah
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Endometrial Carcinoma ◽  
Pelvic Mass ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Accurate Identification ◽  
Female Patients ◽  
Pelvic Masses ◽  
Operative Findings

Background & Method: Study was conducted at Mediciti Institute of Medical Sciences, Medchal, Telangana number of cases studied 30. All clinically suspected female patients with pelvic masses referred to the Department of Radio-diagnosis were evaluated. These patients were first subjected to Ultrasonography followed by MRI (plain and contrast where ever required). MRI findings were compared with that of Ultrasonography. These findings were compared with that of operative findings and histopathological findings wherever performed. Result: Majority of uterocervical lesions on MRI were malignant in nature. One case of endometrial polyp in usg, diagnosed as stage Ib endometrial carcinoma, and cervical fibroid was diagnosed as cervical carcinoma stage II, on MRI 2cases of cervical and 2 cases of endometrial carcinoma. Conclusion: In practice USG is the primary modality for diagnosing the pelvic mass. MRI is superior to ultrasound and can be used as problem solving tool in the assessment of pelvic mass. The multiplanar imaging capability allows accurate identification of origin of mass, characterization of mass(solid, haemorrhagic, fatty and fibrous contents).This may obviate surgery or significantly contribute to the preoperative planning of pelvic  mass Keywords: Magnetic Resonance Imaging, pelvic & female. Study Designed: Observational Study

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