scholarly journals The Use of Endoscopic Ultrasonography and Other Imaging Modalities in the Preoperative Staging of Rectal Villous Tumours: A Case of Overstaging by Magnetic Resonance Imaging

2009 ◽  
Vol 23 (9) ◽  
pp. 639-641 ◽  
Author(s):  
Michelle Buresi ◽  
Iman Zandieh ◽  
Alexander G Nagy ◽  
Audrey Spielmann ◽  
William C Yee ◽  
...  

A case of a 60-year-old man with recurrent rectal villous adenoma is described. Preoperative staging with endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI) revealed very discordant results. EUS showed a tumour present in the mucosa with no submucosal invasion, while MRI revealed invasion of the muscularis propria consistent with an invasive stage T2 carcinoma. Based on the MRI findings, the patient underwent a low anterior resection of the tumour. The surgical pathology specimen revealed a villous adenoma with low-grade dysplasia but no carcinoma and no extension into the muscularis propria. The present case highlights the uncertainty that currently exists as to which imaging modality provides the greatest accuracy in the staging of rectal cancer and in guiding the type of surgical procedure performed. Two recent meta-analyses and a systematic review of the literature point to EUS as the imaging modality of choice for determining muscularis propria and perirectal tissue invasion, as well as nodal involvement.

2018 ◽  
Vol 6 (1) ◽  
pp. 62-65
Author(s):  
Bipan Shrestha ◽  
Kishor Man Shrestha ◽  
Alok Pandey

Introduction: Pyogenic sacroiliitis accounts for 12% of all cases of septic arthritis with less than 200 cases reported in the English literature since the beginning of the twentieth century. Considerable delay between presentation and diagnosis is seen because of unusual presentation and diagnostic dilemma. Cultures of joint fluid usually grow Staphylococcus aureus. Magnetic resonance imaging has been found to be the most useful imaging modality in diagnosis. Being very uncommon disease in children, the key to successful management is early diagnosis in which computed tomography (CT), bone scans, and magnetic resonance imaging (MRI) findings play a crucial role. If the diagnosis is established promptly, most patients can be managed successfully with antimicrobial therapy with excellent prognosis. Most reported cases required prolonged antimicrobial therapy of six to nine weeks. Presented here is a child with pyogenic sacroiliitis managed at our hospital (Universal College of Medical Sciences Teaching Hospital-UCMSTH) and review of the literature on this relatively rare diagnosis. Journal of Universal College of Medical SciencesVol. 6, No. 1, 2018, Page: 62-65


2013 ◽  
Vol 47 (3) ◽  
pp. 244-246 ◽  
Author(s):  
Evrim Ozmen ◽  
Güven Güney ◽  
Oktay Algin

Abstract Background. Dermatofibrosarcoma protuberans (DFSP) of the vulva is a rare low-grade soft tissue sarcoma. Magnetic resonance imaging (MRI) findings of vulvar DFSP were essentially unreported in the literature. Case report. We report a DFSP of vulva with its clinical, histological and MRI features. As far we know this is the first case of histologically confirmed vulvar DFSP presenting with MR images. The diagnosis of DFSP is usually made by histopathologic and clinical findings. Conclusions. MRI is useful both for the diagnosis of DFSP and following up the patients since it has high soft tissue resolution and no risk of radiation exposure. With MRI the relation to the adjacent anatomical structures, extension and depth of the tumour and possible lymph node involvement can also be demonstrated.


Author(s):  
Vanda F. Torous ◽  
Nancy A. Resteghini ◽  
Jordana Phillips ◽  
Vandana Dialani ◽  
Priscilla J. Slanetz ◽  
...  

Context.— Dynamic, contrast-enhanced magnetic resonance imaging (MRI) is a highly sensitive imaging modality used for screening and diagnostic purposes. Nonmass enhancement (NME) is commonly seen on MRI of the breast. However, the pathologic correlates of NME have not been extensively explored. Consequently, concordance between MRI and pathologic findings in such cases may be uncertain and this uncertainty may cause the need for additional procedures. Objective.— To examine the histologic alterations that correspond to NME on MRI. Design.— We performed a retrospective search for women who underwent breast MRI between March 2014 and December 2016 and identified 130 NME lesions resulting in biopsy. The MRI findings and pathology slides for all cases were reviewed. The follow-up findings on any subsequent excisions were also noted. Results.— Among the 130 cases, the core needle biopsy showed 1 or more benign lesions without atypia in 80 cases (62%), atypical lesions in 21 (16%), ductal carcinoma in situ in 22 (17%), and invasive carcinoma in 7 (5%). Review of the imaging features demonstrated some statistically significant differences in lesions that corresponded to malignant lesions as compared with benign alterations, including homogeneous or clumped internal enhancement, type 3 kinetics, and T2 dark signal; however, there was considerable overlap of features between benign and malignant lesions overall. Of 130 cases, 54 (41.5%) underwent subsequent excision with only 6 cases showing a worse lesion on excision. Conclusions.— This study illustrates that NME can be associated with benign, atypical, and/or malignant pathology and biopsy remains indicated given the overlap of radiologic features.


Author(s):  
Nao Kikkawa ◽  
Kimiteru Ito ◽  
Hiroshi Yoshida ◽  
Mayumi Kobayashi Kato ◽  
Yuko Kubo ◽  
...  

Abstract Purpose We evaluated magnetic resonance imaging (MRI) findings of dedifferentiated endometrial carcinoma (DEC), comprising undifferentiated carcinoma and low-grade endometrioid carcinoma. Materials and methods We recruited 11 patients with pathologically proven DEC treated at our institute. We evaluated primary lesion size, location and signal intensity on MRI, and prognosis. MRI and pathological findings were compared in eight resected patients. Results Primary tumors ranged from 16 to 206 mm in diameter. DEC was located at the endometrium in 9 of the 11 patients; the remaining two patients showed diffuse involvement of the enlarged myometrium. These two patients with diffuse involvement type died within 4 months. Of the eight patients who underwent resection, seven had macroscopic intratumoral hemorrhage and six showed a high signal on T1-weighted images or low signal on T2-weighted images. Of the eight resected patients, four had tumor necrosis > 25% and tumor size > 5 cm. In these patients, necrosis appeared as nonenhanced areas on contrast-enhanced MRI. Conclusion MRI findings of DEC showed two patterns: mass-forming type and diffuse myometrial type with poor prognosis. Most patients with DEC had intratumoral hemorrhage, and large tumors (> 5 cm) had gross necrosis, which appeared as nonenhanced areas on contrast-enhanced MRI.


2018 ◽  
Vol 108 (6) ◽  
pp. 472-477
Author(s):  
Nicholas Ciotola ◽  
William D. Spielfogel

Background: Magnetic resonance imaging (MRI) is both sensitive and specific in the diagnosis of osteomyelitis, and it is an important imaging modality in preoperative planning of resection of infected bone. In many cases, however, the extent of osseous infection is evident on plain radiographs, and little additional information is gained from the MRI. The goal of this study was to assess the accuracy of radiographs against MRIs in assessing the spread of suspected osteomyelitis from one phalanx to another or to a metatarsal. Methods: A medical record review was performed, and 14 patients with 16 toes confirmed to have osteomyelitis involving one or more phalanges were included in the study. An investigator blinded to the MRI findings interpreted the extent of osseous involvement based solely on the radiographic and clinical presentation. The accuracy of the radiographic interpretation was then calculated against the MRI findings. Results: In 14 of the 16 toes (87.5%), whether osteomyelitis had spread from one bone to another was determined based on the radiographic and clinical presentation. In one toe, the radiograph did not adequately depict osteomyelitis in adjacent infected bone. In one more toe, the radiograph depicted features of osteomyelitis in uninfected bone. Conclusions: In a large percentage of patients, the phalanges affected by osteomyelitis had visible findings on the radiograph, and operative planning could have been based on the radiograph alone.


2020 ◽  
Vol 6 (4) ◽  
pp. 391-401
Author(s):  
JA Akinmoladun ◽  
GI Ogbole ◽  
ID Famosaya ◽  
RU Joel

Background: Seizure is the most common neurological disorder in children and an important cause of paediatric hospital admission with the highest prevalence in the under-five age group. Magnetic Resonance Imaging (MRI) is the neuro-imaging technique of choice in the initial evaluation of children with epilepsy. High-field MRI is the ideal imaging modality for evaluating seizures but this is not readily available in developing countries. Objective: To analyse the spectrum of MRI findings in children presenting with seizures using a low-field (0.36T) MRI. Methods: Children aged ≤18years with seizures, with cranial MRI at the University College Hospital (UCH), Nigeria between January 2013 and June 2015 were retrospectively reviewed. Results: There were a total of 134 patients with 53% as adolescents and most of them (85; 63.4%) had abnormal cranial MRI findings. More male children had abnormal findings (52; 61.2%) and most abnormal findings (42; 49.4%) were reported among adolescents. The most frequent abnormality was hydrocephalus (23.5%) from various causes followed by cerebral tumours (14.1%) and ischaemic cerebral infarcts (11.8%). In the adolescents, intracranial tumours (21.4%) were the most frequent abnormal findings, while hydrocephalus was commoner in children aged less than 10 years, accounting for 33.3% and 36.0% among the 1-5 years and 6-11 years age groups respectively. Conclusion: Low-field MRI, which is more readily available, can provide substantial preliminary findings to aid the management of children with epilepsies. Improved access to high-field MRI through cost reduction and early MR imaging evaluation in the course of illness are desirable.


2012 ◽  
Vol 102 (3) ◽  
pp. 184-186 ◽  
Author(s):  
Muhammad Ali Fazal ◽  
Ishrat Khan ◽  
Cherian Thomas

Background: Magnetic resonance imaging (MRI) and ultrasonography are used widely for the diagnosis of Morton’s neuroma. The aim of this study was to assess the accuracy of these two modalities as diagnostic tools in Morton’s neuroma. Methods: Fifty feet of 47 consecutive patients (39 women and 8 men; mean age, 46 years; age range, 36–64 years) who presented between January 1, 2005, and June 30, 2008, were included in the study. Twenty-five feet were investigated with ultrasonography and 25 with MRI. Morton’s neuroma was confirmed surgically and histologically in all of the patients. A Student unpaired t test was applied. Results: Twenty-two MRIs were diagnostic (sensitivity, 88%). Three patients with negative MRI findings underwent ultrasonography and were found to have a neuroma smaller than 5 mm. Twenty-four ultrasound scans demonstrated the neuroma (sensitivity, 96%), with five neuromas being smaller than 5 mm. Conclusions: Ultrasonography has a slightly higher sensitivity in the diagnosis of Morton’s neuroma, particularly of neuromas smaller than 5 mm, and should be the preferred imaging modality in suspected cases, and MRI should be reserved for cases with equivocal diagnosis. (J Am Podiatr Med Assoc 102(3): 184–186, 2012)


2021 ◽  
Vol 8 (14) ◽  
pp. 915-919
Author(s):  
Kaushal B ◽  
Chandrashekar H.M ◽  
Shobhalakshmi C.S ◽  
Vijakumar K.R

BACKGROUND The sellar and juxtasellar region is a complex area where varied pathologies can occur. Differentiation among various pathologies may not always be easy, since many of these lesions mimic pituitary adenomas on clinical presentation, endocrinologic and radiologic examinations. The study intends to describe the imaging characteristics of the spectrum of pathological conditions affecting these regions using magnetic resonance imaging (MRI). METHODS The main source of data for the study were patients from hospitals attached to Bangalore Medical College and Research Institute, Bengaluru viz. Victoria Hospital, Bowring and Lady Curzon Hospital and Vani Vilas Hospital. Patients with suspected sellar and juxtasellar pathology on clinical examination referred to the Department of Radiodiagnosis from November 2017 to May 2019 underwent MRI study using Siemens 1.5-T Magnetom Avanto MR system. Magnetic resonance imaging was done in all patients according to the pituitary protocol. RESULTS Among the 50 patients, there were 16 males and 34 females. Most of the patients were in the third to fifth decade of life. The various abnormalities on MRI included neoplastic (68 %), malformative (8 %), vascular (6 %), granulomatous, infectious and inflammatory (18 %) lesions. Pituitary adenomas (46 %) were the most common lesions in sellar and juxtasellar regions, followed by tuberculosis (10 %), craniopharyngioma (8 %), Rathke's cleft cyst (6 %), meningioma (6 %), internal carotid artery (ICA) aneurysm (4 %), epidermoid (2 %) and miscellaneous lesions. CONCLUSIONS MR imaging characteristics were sufficiently distinct to allow various sellar and juxtasellar pathologies to be differentiated from each other. The spectrum of MRI findings were related to neoplastic, malformative, infectious, inflammatory, granulomatous and vascular causes. Our study observed that MRI with appropriate imaging protocols is the essential imaging modality in evaluation of sellar and juxtasellar lesions. KEYWORDS Pituitary, Sellar, Juxtasellar, Magnetic Resonance Imaging


2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Behnaz Moradi ◽  
Narges Izadi-Mood ◽  
Mohammadreza Chavoshi ◽  
Elham Shirali ◽  
Fariba Yarandi ◽  
...  

: Uterine cavernous hemangioma is a rare vascular tumor that is more commonly reported as an acquired disease in pregnant women. Rarity of the case impeded the radiologist to be able to find characteristic imaging findings to diagnose the disease before surgery. We report a 40-year-old premenopausal woman with cavernous hemangioma of the uterus that was misdiagnosed as a low-grade sarcoma because of the non- typical imaging feature of this pathology that has not been reported before. The ultrasound exam of the patient only demonstrated global enlargement of the myometrium. Magnetic resonance imaging (MRI) showed diffuse myometrial edema with multiple linear low signal strands, without endometrial involvement and with mild restriction in diffusion-weighted imaging (DWI) that resulted in a lobulated border of uterine contour. MRI could be a helpful imaging modality for proper diagnosis of uterine hemangioma before surgery.


Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.


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