Effect of Chinese herbal treatment on Th1- and Th2-type cytokines, progesterone and β-human chorionic gonadotropin in early pregnant women of threatened abortion

2009 ◽  
Vol 15 (5) ◽  
pp. 353-358 ◽  
Author(s):  
Fang Liu ◽  
Song-ping Luo
Keyword(s):  
Pregnant Women ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Herbal Treatment ◽  
Chinese Herbal ◽  
Threatened Abortion ◽  
Th1 And Th2

No effect of human chorionic gonadotropin treatment due to threatened abortion in early pregnancy for birth outcomes

Open Medicine ◽  
2008 ◽  
Vol 3 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Andrew Czeizel ◽  
István Dudás ◽  
János Gidai ◽  
Erzsébet Horváth-Puhó
Keyword(s):  
Preterm Birth ◽  
Pregnant Women ◽  
Spontaneous Abortion ◽  
Chorionic Gonadotropin ◽  
Early Pregnancy ◽  
Human Chorionic Gonadotropin ◽  
Low Birthweight ◽  
Preterm Births ◽  
Data Set ◽  
Threatened Abortion

AbstractHuman chorionic gonadotropin (HCG) is used parenterally for treatment of threatened abortions and repeated spontaneous abortion in pregnant women. No controlled epidemiological studies of preterm birth and low birthweight newborns in pregnant women with HCG treatment have been published while the results of animal investigations were controversial. The data of 97 pregnant women with HCG treatment in the second and third months of pregnancy due to threatened abortion and/or previous spontaneous abortion(s) was compared with the data of other 38,054 pregnant women in the population-based large data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities. There was no difference in mean gestational age at delivery and birth weight, in addition the rate of preterm birth and low birthweight newborns. Parenteral HCG treatment in the early pregnancy due to threatened abortion did not associate with a higher risk for preterm births or low birthweight newborns. However, a higher occurrence of gestational diabetes was found in pregnant women with HCG treatment and there was a slight male excess among newborn infants (p=0.06).

The Value of β - Human Chorionic Gonadotropin , Progesterone and CA - 125 in Prediction of Outcome in Threatened Abortion

2013 ◽  
Vol 64 (7-9) ◽  
pp. 501-508
Author(s):  
Ahmed Ramy Mohamed Ramy ◽  
Abdel-Megeed Ismail Abdel-Megeed ◽  
Tarek Aly Raafat ◽  
Ahmed Mahmoud Ahmed Hussein
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Ca 125 ◽  
Prediction Of Outcome ◽  
Threatened Abortion

Thyroid-stimulating activity of human chorionic gonadotropin in sera of normal pregnant women

1990 ◽  
Vol 123 (3) ◽  
pp. 277-281 ◽  
Author(s):  
Masayoshi Yoshimura ◽  
Mitsushige Nishikawa ◽  
Masateru Horimoto ◽  
Norio Yoshikawa ◽  
Susumu Sawaragi ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Dependent Manner ◽  
Camp Accumulation ◽  
Serum Samples ◽  
Adenylate Cyclase Activation ◽  
Thyrotropic Activity ◽  
Camp Levels ◽  
Dose Dependent

Abstract. To ascertain the thyrotropic activity of human chorionic gonadotropin in sera of normal pregnant women, we examined the adenylate cyclase activation in the cultured FRTL-5 cells by extracted hCG from 7 normal pregnant women. hCG was extracted from the sera using anti-hCG-β subunit monoclonal antibodycoated microwells, eluted with 2 mol/l guanidine-HCl, and reconstituted with hypotonic Hanks' solution. FRTL-5 cells were precultured in 5H medium, incubated for 2 h with the serum extracts, and the cAMP released into the medium was measured. hCG levels in serum extracts ranged from 1100 to 6800 IU/l; values corresponded to 1.4-19.8% compared with those in the original serum samples. Addition of the extracts to FRTL-5 cells resulted in significant increases in the cAMP accumulation, ranging from 9.8 to 59.0 nmol/l. cAMP levels were also increased in a dose-dependent manner by adding purified hCG as well as crude hCG and hTSH to FRTL-5 cells. These findings suggest that the thyroid gland of normal pregnant women may actually be stimulated by hCG itself.

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