Adolescents and primary herpetic gingivostomatitis: an Italian overview

Abstract Aim The aim of this study was to investigate the therapies administered to Italian adolescents with primary herpetic gingivostomatitis (PHGS) Methods The medical records of 74 adolescents with PHSG were reviewed. The following data were recorded: age, gender, day of onset, type of treatment, lesions’ severity, pain scoring, eating, and drinking ability. The oral examination was performed at the first evaluation (T0) and after one week (T1). Results All patients showed up at the first visit at least 48 h after the onset of symptoms. No patient was prescribed an antiviral therapy. An antibiotic therapy was prescribed in order to prevent secondary bacterial infections. Fifteen patients had been treated with non alcoholic chlorhexidine rinses (group A), 29 patients with non alcoholic chlorhexidine rinses plus hyaluronic acid gel (group B); 30 patients with non alcoholic chlorhexidine rinses plus Mucosyte® (group C). A significant improvement of the pain scoring and lesions’ severity was noted in group C. Conclusion In Italian adolescents, PHGS is diagnosed at least 48 h after onset and the antibiotic therapy is widely prescribed in order to prevent overinfections. Among topical therapies, an association of verbascoside and sodium hyaluronhate seems to favour a faster healing.

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Nonsurgical Treatment of Abnormal Eyelid Position Using Hyaluronic Acid Gel

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2012.53.3.357 ◽

2012 ◽

Vol 53 (3) ◽

pp. 357

Author(s):

Seok Joong Chung ◽

Hyun Min Shin ◽

Helen Lew

Keyword(s):

Hyaluronic Acid ◽

Nonsurgical Treatment ◽

Acid Gel ◽

Hyaluronic Acid Gel

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Does Adjunctive Use of Hyaluronic Acid Improve Clinical Outcome of Mechanical Therapy for Cases of Mild Aggressive Periodontitis

Revista de Chimie ◽

10.37358/rc.17.3.5513 ◽

2017 ◽

Vol 68 (3) ◽

pp. 612-614

Author(s):

Andreea A. Pogan ◽

Roxana Buzatu ◽

Dan Onisei ◽

Doina Onisei

Keyword(s):

Hyaluronic Acid ◽

Antimicrobial Effect ◽

Aggressive Periodontitis ◽

Gingival Tissue ◽

Potential Benefits ◽

Therapeutic Properties ◽

Acid Gel ◽

Mechanical Therapy ◽

Improve Clinical Outcome ◽

Hyaluronic Acid Gel

Hyaluronic acid is an essential component of the periodontal ligament matrix and it has shown a number of clinical therapeutic properties, especially an anti-inflammatory effect on the gingival tissue. The aim of this study is to evaluate the potential benefits of using hyaluronic acid gel in topical application as an adjunct to mechanical therapy in the management of aggressive periodontitis. Results show an obvious improvement of clinical parameters, especially regarding the evolution of healing of the gingival tissue after periodontal therapy. Nevertheless, the antimicrobial effect needs to be proven in further studies.

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CLINICAL APPLICATION OF RADIESSE AND HYALURONIC ACID GEL FOR TREATMENT OF PAPILLAE DEFICIENCIES IN THE ESTHETIC ZONE

Egyptian Dental Journal ◽

10.21608/edj.2017.75003 ◽

2017 ◽

Vol 63 (1) ◽

pp. 533-545

Author(s):

Heba Shawky ◽

Mahinour Darwish

Keyword(s):

Hyaluronic Acid ◽

Clinical Application ◽

Acid Gel ◽

Hyaluronic Acid Gel

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Comparative study between two empirical antibiotic regime in the management of childhood malignancy with fever

Northern International Medical College Journal ◽

10.3329/nimcj.v5i2.23128 ◽

2015 ◽

Vol 5 (2) ◽

pp. 329-331 ◽

Cited By ~ 1

Author(s):

Laila Helaly ◽

Md Zakir Hossain Sarker ◽

MA Mannan ◽

Md Tafazzal Hossain ◽

Shafi Ahmed ◽

...

Keyword(s):

Antibiotic Therapy ◽

Study Drug ◽

Successful Outcome ◽

Medical College ◽

Pediatric Hematology ◽

Pediatric Cancer Patients ◽

Group A ◽

Study Population ◽

Group B ◽

Oncology Unit

Objective : The present prospective randomized clinical trial was carried out to assess whether combined cefepime and amikacin as empirical antibiotic therapy was more effective than combined ceftriaxone and gentamicin in the treatment of febrile neutropenic children with malignant diseases.Material & Methods : The study was conducted in the Pediatric Hematology and Oncology unit of BSMMU over a period of 2 years. (From January 2006 to December 2007) Hospitalised pediatric cancer patients who developed febrile neutropenia following chemotherapy or radiotherapy were the study population. A total 64 cases were consecutively included in the study and were randomly assigned to either cefepime & amikacin group (Group- A) or ceftriaxone & gentamicin group (Group-B). The Group-A received cefepime 1500 mg/m2/dose infused over 15 minutes in two divided doses intravenously(IV) while amikacin was administered as thrice daily dose of 200 mg/m2/dose. Patients of Group-B received ceftriaxone 1500 mg/m2/dose in two divided doses and gentamicin 60 mg/m2/dose thrice daily IV. The therapy was continued until absolute neutrophil counts reached >1000 neutrophils/mm3. The treatment outcome was considered successful if fever resolves within 4 days and does not recur within 7 days of completion of therapy. Of the 64 patients, 13 cases were excluded from the final analysis.Results : Bacteria were isolated from culture in only 16.7% of cases Group-A and 9.5% of group-B. Patients E. coli was the most common isolate found in blood specimen (37%). Following intervention, 90% of cefepime & amikacin group and 85.6% of ceftriaxone & gentamicin group improved absolute neutrophil count to >1000/mm3 of blood. Persistence of fever after start of study drug and duration of antibiotic therapy were significantly less in the former group than those in later group (p = 0.049 and p = 0.004 respectively). Only 1 patient of group B had recurrence of infection within 7 days of treatment completion. The mean duration of hospital stay was less in the former group (7.97 ± 2.61 days) than that in the latter group (11.00 ± 3.42 days) (p = 0.06). Evaluation of final outcome shows that majority (86.6%) of cefepime & amikacin group had successful outcome, while majority of ceftriaxone & gentamicin group (81%) failed to resolve infection with continuation of fever for > 4 days.Conclusion : The study concluded that combined cefepime and amikacin is a better option for empirical treatment of fever and neutropenia in children with malignancies than combined ceftriaxone and gentamicin (p<0.001).Northern International Medical College Journal Vol.5(2) 2014: 329-331

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