scholarly journals Challenges and Opportunities in Multimodal Monitoring and Data Analytics in Traumatic Brain Injury

2021 ◽  
Vol 21 (3) ◽  
Author(s):  
Brandon Foreman ◽  
India A Lissak ◽  
Neha Kamireddi ◽  
Dick Moberg ◽  
Eric S Rosenthal
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Data Analytics ◽  
Multimodal Monitoring ◽  
Challenges And Opportunities

Challenges and Opportunities for Neuroimaging in Young Patients with Traumatic Brain Injury: a Coordinated Effort towards Advancing Discovery from the ENIGMA Pediatric Moderate/Severe TBI Group

2019 ◽  
Author(s):  
Emily L. Dennis ◽  
Karen Caeyenberghs ◽  
Robert F. Asarnow ◽  
Talin Babikian ◽  
Brenda Bartnik-Olson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Meta Analysis ◽  
Young Patients ◽  
Future Research ◽  
Childhood And Adolescence ◽  
Developmental Issues ◽  
Challenges And Opportunities ◽  
Severe Tbi ◽  
Advance Research

Traumatic brain injury (TBI) is a major cause of death and disability in children in both developed and developing nations. Children and adolescents suffer from TBI at a higher rate than the general population; however, research in this population lags behind research in adults. This may be due, in part, to the smaller number of investigators engaged in research with this population and may also be related to changes in safety laws and clinical practice that have altered length of hospital stays, treatment, and access to this population. Specific developmental issues also warrant attention in studies of children, and the ever-changing context of childhood and adolescence may require larger sample sizes than are commonly available to adequately address remaining questions related to TBI. The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Pediatric Moderate-Severe TBI (msTBI) group aims to advance research in this area through global collaborative meta-analysis. In this paper we discuss important challenges in pediatric TBI research and opportunities that we believe the ENIGMA Pediatric msTBI group can provide to address them. We conclude with recommendations for future research in this field of study.

Coordinating Global Multi-Site Studies of Military-Relevant Traumatic Brain Injury: Opportunities, Challenges, and Harmonization Guidelines

2019 ◽  
Author(s):  
David F Tate ◽  
Emily L. Dennis ◽  
John T Adams ◽  
Maheen Adamson ◽  
Heather G Belanger ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Meta Analysis ◽  
Natural Aging ◽  
Prognostic Accuracy ◽  
Challenges And Opportunities ◽  
Imaging Markers ◽  
Conducting Research ◽  
Return To Duty ◽  
Neuroimaging Genetics

Traumatic brain injury (TBI) is common among military personnel and is often followed by a heterogeneous array of clinical, cognitive, behavioral, mood, and neuroimaging changes. This inconsistent presentation makes it difficult to establish or validate biological and imaging markers that could help improve diagnostic and prognostic accuracy in this patient population. The purpose of this manuscript is to describe both the challenges and opportunities when conducting research with Service Members and Veterans and introduce the Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Military Brain Injury working group. ENIGMA is a worldwide consortium focused on improving replicability and analytical power through data sharing and collaboration. In this paper, we discuss challenges affecting efforts to aggregate data in this patient group. In addition, we highlight how “big data” approaches might be used to understand better the role that each of these variables might play in the imaging and functional phenotypes of TBI in Service Member and Veteran populations, and how data may be used to examine important military specific issues such as return to duty, the late effects of combat-related injury, and alteration of the natural aging processes.

Bioengineering in Brain Trauma Research

Neurotrauma ◽  
2018 ◽  
pp. 347-358
Author(s):  
Michelle C. LaPlaca
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Problem Solving ◽  
Injury Prevention ◽  
Data Analytics ◽  
Imaging Biomarkers ◽  
Injury Biomechanics ◽  
Problem Solving Skills ◽  
Trauma Research ◽  
Quantitative Analyses

The study of traumatic brain injury (TBI) encompasses research spanning from injury prevention to clinical interventions, all of which have been influenced by bioengineering. Bioengineering uses quantitative analyses and problem-solving skills to approach the complexity of many areas of neurotrauma research including injury biomechanics, imaging, biomarkers, and data analytics. This chapter presents basic bioengineering concepts, highlights significant contributions to neurotrauma research, and discusses opportunities in the field that may lend themselves to bioengineering solutions. The intention of the author is to promote an appreciation of engineering and to catalyze problem-solving among readers, engineers and non-engineers alike.

Multimodal Monitoring After Traumatic Brain Injury

2015 ◽  
Vol 43 (2) ◽  
pp. 506-507 ◽  
Author(s):  
J. Paul Muizelaar
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Multimodal Monitoring

scholarly journals Mobile Monitoring of Traumatic Brain Injury in Older Adults: Challenges and Opportunities

2017 ◽  
Vol 15 (3) ◽  
pp. 227-230
Author(s):  
Andrei Irimia ◽  
Susan Wei ◽  
Nanshu Lu ◽  
Constance M. Moore ◽  
David N. Kennedy
Keyword(s):  
Older Adults ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mobile Monitoring ◽  
Challenges And Opportunities

Accuracy of Brain Multimodal Monitoring to Detect Cerebral Hypoperfusion After Traumatic Brain Injury*

2015 ◽  
Vol 43 (2) ◽  
pp. 445-452 ◽  
Author(s):  
Pierre Bouzat ◽  
Pedro Marques-Vidal ◽  
Jean-Baptiste Zerlauth ◽  
Nathalie Sala ◽  
Tamarah Suys ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cerebral Hypoperfusion ◽  
Multimodal Monitoring
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