Comparison of Optical Coherence Biometry and Applanation Ultrasound Biometry in High-Myopic eyes with Posterior Pole Staphyloma

Abstract Purpose: To study the topographic distribution of the short posterior ciliary arteries (SPCA) entry sites into the choroid in normal eyes using structural en-face swept source optical coherence tomography (SS-OCT). Methods: Retrospective analysis of SS-OCT scans (wide-field structural SS-OCT 12x12mm) of 13 healthy subjects was performed. Cross-sectional swept-source OCT scans derived from a volume scan were represented as en-face image display following the Choroid-Scleral Interface to obtain en-face OCT. SPCAs in their last scleral location before choroidal entrance were identified manually, counted and localized by two masked observers. Correlations between two masked observers were analyzed using inter- and intra- class correlation. Results: Accuracy for the choroidal inner and outer border segmentation was 95-99%. Eighteen eyes from 13 normal subjects were included for SPCA analysis. The mean number of arteries was 13.8±3.5 per eye. Thirty-six percent were in the center of the posterior pole image; however, 21% were in the temporal part of the posterior pole. Median accuracy of the detection is 0.94. The correlation between the two observers was fair (0.54).Conclusion: Our algorithm allows visualization of the SPCA at the posterior pole of the eye using wide-field en-face SS-OCT. It can also help the clinicians to study the SPCAs in numerous ocular diseases, particularly its relationship with focal choroidal diseases.

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Optical Coherence Tomography Findings of Exophytic Retinal Capillary Hemangiomas of the Posterior Pole

Ophthalmic Surgery Lasers and Imaging ◽

10.3928/15428877-20100215-30 ◽

2010 ◽

Cited By ~ 3

Author(s):

Eric K. Chin ◽

Rupan Trikha ◽

Lawrence S. Morse ◽

Robert J. Zawadzki ◽

John S. Werner ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Posterior Pole ◽

Optical Coherence ◽

Retinal Capillary

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Correlation of choriocapillaris hemodynamic data from dynamic indocyanine green and optical coherence tomography angiography

Scientific Reports ◽

10.1038/s41598-021-95270-6 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Chui Ming Gemmy Cheung ◽

Kelvin Yi Chong Teo ◽

Sai Bo Bo Tun ◽

Joanna Marie Busoy ◽

Veluchamy A. Barathi ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Indocyanine Green ◽

Optical Coherence Tomography Angiography ◽

Posterior Pole ◽

Uniform Mesh ◽

Optical Coherence ◽

Choroidal Blood Flow ◽

Filling Sequence ◽

Filling Pattern ◽

Choroidal Vasculature

AbstractTo investigate the correlation between posterior pole choroidal blood flow evaluated with digital subtraction indocyanine green angiography and enface optical coherence tomography angiography (OCTA). Imaging in animal study. The anatomy of 2 cynomogulus monkeys was studied. Each monkey was given a 0.75 mg/kg injection of indocyanine green in the saphenous vein. The dynamic angiographic filling sequence was recorded at 15 frames per second using the Heidelberg Spectralis. After image registration, sequential frame subtraction was used to image the dye front moving through the choroid. The OCTA was obtained by frame averaging nine separate choriocapillaris slab flow images obtained from the Zeiss Plex Elite 9000. Posterior pole choriocapillaris filling pattern in relation to the choriocapillaris anatomy as imaged by OCTA. In the posterior pole, the choriocapillaris fills in the pattern of discrete units with variable sizes and shapes. The cycle of dye filling begins in the peripapillary area and progresses toward the periphery in a wavelike manner. This filling pattern repeats in a cyclical manner, consistent with the cardiac cycle. OCTA shows a uniform mesh of vessels. While OCTA shows a uniform meshwork appearance of the choriocapillaris, the dynamic dye angiography suggests an irregular configuration of functional units partitioned by pressure gradients as opposed to structural boundaries. Disturbance of local perfusion pressure within choroidal vasculature may result in abnormal flow patterns, which could be evaluated in the clinic using commercially available equipment.

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Diagnostic accuracy of posterior pole asymmetry analysis parameters of spectralis optical coherence tomography in detecting early unilateral glaucoma

Indian Journal of Ophthalmology ◽

10.4103/0301-4738.171965 ◽

2015 ◽

Vol 63 (11) ◽

pp. 837 ◽

Cited By ~ 7

Author(s):

Paaraj Dave ◽

Juhi Shah

Keyword(s):

Optical Coherence Tomography ◽

Diagnostic Accuracy ◽

Posterior Pole ◽

Optical Coherence ◽

Asymmetry Analysis ◽

Pole Asymmetry

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Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography

Journal of Ophthalmology ◽

10.1155/2019/2406547 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6

Author(s):

Yong Un Shin ◽

Ji Hong Kim ◽

Heeyoon Cho ◽

Dae Sung Kim ◽

Joo-Hark Yi ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Anterior Segment ◽

Posterior Pole ◽

Wide Field ◽

Inner Plexiform Layer ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Fiber Layer ◽

Chamber Angle

Purpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients who underwent HD for ESKD. Anterior chamber angle images were obtained by 16 mm line scan of ASOCT. The angle opening distance (AOD) and the trabecular-iris space area (TISA) were determined using the ImageJ program. Additional 12 mm horizontal and 9 mm vertical wide-field scans centered on the posterior pole were performed for the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness. Changes in intraocular pressure (IOP), AOD, TISA, pRNFL thickness, and mGCIPL thickness before and after HD were statistically analyzed. Results. The IOP decreased significantly from 17.5 ± 3.4 before HD to 16.2 ± 2.3 after HD (P=0.017). There was a statistically significant decrease in AOD 750 and TISA 750 (P=0.005 and P=0.007, respectively). AOD 500 and TISA 500 also decreased, which was almost statistically significant (P=0.061 and P=0.081, respectively). Mean pRNFL thickness and mGCIPL thickness did not show significant change after HD. Conclusion. We observed a significant decrease in IOP and anterior chamber angle measurements after HD. Our study suggests that HD can influence the anterior segment structure of eyes.

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Certain chorioretinal parameters of the eye in congenital and acquired myopia and their relationship with anatomical and optical parameters

Russian Ophthalmological Journal ◽

10.21516/2072-0076-2021-14-3-46-53 ◽

2021 ◽

Vol 14 (3) ◽

pp. 46-53

Author(s):

E. P. Tarutta ◽

R. R. Khubieva ◽

G. A. Markosyan

Keyword(s):

Structural Changes ◽

Morphological Changes ◽

Nerve Fibers ◽

Posterior Pole ◽

Control Group ◽

Optical Parameters ◽

Optical Coherence ◽

Hemodynamic Parameters ◽

Structural Disorders ◽

Optical Coherence Tomograph

Purpose: to assess the thickness of the central region of the retina and choroid, the layer of nerve fibers in the macular and peripapillary regions, the density of the superficial and deep plexus of the retina and the choroid in congenital and acquired myopia and see how they are related with the refraction and axial length of the eye.Material and methods. 33 patients aged 6 to 16 (averagely, 12.07 ± 3.09 years) were divided into 3 groups: 1) with congenital myopia (23 eyes), 2) with acquired myopia (9 eyes), and 3) the control group with emmetropia (20 eyes). Chorioretinal and hemodynamic parameters were determined using an RS-3000 Advance 2 spectral optical coherence tomograph (Nidek, Japan). Correlation analysis was performed using Pearson’s linear correlation coefficient (r).Results. Structural changes in the sensory and vascular membranes of the eye were revealed in both myopic groups as compared to the control group. Of the two clinical groups, more severe structural disorders were found in congenital myopia. Hemodynamic parameters revealed abnormalities in the deep retinal layers, as well as in the choriocapillary layer. The comparative analysis showed that morphological changes in the posterior pole have a stronger correlation with anatomical parameters as compared to optical ones.Conclusion. Optical coherence tomography is an informative method of differential diagnosis, monitoring, and prognostication of changes in the posterior pole in myopia.

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