Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long after Parturition

2019 ◽  
Vol 15 (4) ◽  
pp. 519-529 ◽  
Author(s):  
Cosmin Andrei Cismaru ◽  
Olga Soritau ◽  
Ancuta - Maria Jurj ◽  
Raduly Lajos ◽  
Bogdan Pop ◽  
...  
Stem Cells ◽  
2006 ◽  
Vol 24 (12) ◽  
pp. 2840-2850 ◽  
Author(s):  
Maria Beatriz Herrera ◽  
Stefania Bruno ◽  
Stefano Buttiglieri ◽  
Ciro Tetta ◽  
Stefano Gatti ◽  
...  

2012 ◽  
Vol 3 (1) ◽  
pp. 8-18 ◽  
Author(s):  
Hao Long ◽  
Shulin Zhang ◽  
Chunqi Liu ◽  
Jianlin Shi ◽  
Liyang Tao ◽  
...  

2011 ◽  
Vol 10 (2) ◽  
pp. 182
Author(s):  
O.G. Ivanovski ◽  
S.K. Saidi ◽  
S.O. Stavridis ◽  
S.A. Dohcev ◽  
O.L. Stankov ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Nedaa Al-Jezani ◽  
Roger Cho ◽  
Anand O. Masson ◽  
Brian Lenehan ◽  
Roman Krawetz ◽  
...  

Study Design. Isolation and characterization of human epidural fat (HEF) stem/progenitor cells. Objective. To identify a progenitor population within HEF and to determine if they meet the minimal criteria of a mesenchymal stem cell (MSC). Summary of Background Data. The biological function, if any, has yet to be determined for HEF. The presence of MSCs within HEF may indicate a regenerative potential within the HEF. Methods. HEF was isolated from 10 patients during elective spinal surgery. HEF cells were differentiated along osteo-, adipo-, and chondrogenic lineages, with differentiation analyzed via qPCR and histology. The cell surface receptor profile of HEF cells was examined by flow cytometry. HEF cells were also assayed through the collagen contraction assay. Prx1CreERT2GFP:R26RTdTomato MSC lineage-tracking mice were employed to identify EF MSCs in vivo. Results. HEF cell lines were obtained from all 10 patients in the study. Cells from 2/10 patients demonstrated full MSC potential, while cells from 6/10 patients demonstrated progenitor potential; 2/10 patients presented with cells that retained only adipogenic potential. HEF cells demonstrated MSC surface marker expression. All patient cell lines contracted collagen gels. A Prx1-positive population in mouse epidural fat that appeared to contribute to the dura of the spinal cord was observed in vivo. Conclusions. MSC and progenitor populations are present within HEF. MSCs were not identified in all patients examined in the current study. Furthermore, all patient lines demonstrated collagen contraction capacity, suggesting either a contaminating activated fibroblast population or HEF MSCs/progenitors also demonstrating a fibroblast-like phenotype. In vivo analysis suggests that these cell populations may contribute to the dura. Overall, these results suggest that cells within epidural fat may play a biological role within the local environment above providing a mechanical buffer.


2008 ◽  
Vol 17 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Sanjleena Singh ◽  
Ben J. Jones ◽  
Ross Crawford ◽  
Yin Xiao

Author(s):  
Paula L. Miliani de Marval ◽  
Sun Hye Kim ◽  
Marcelo L. Rodriguez-Puebla

2019 ◽  
Vol 21 (1) ◽  
pp. 31-46 ◽  
Author(s):  
Lucyene Miguita ◽  
Maria Cristina Zindel Deboni ◽  
Paul Sharpe ◽  
Andrea Mantesso

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Nelson Ian Saddler ◽  
Josh Nederveen ◽  
Tim Snijders ◽  
Sophie Joanisse ◽  
Jeff Baker ◽  
...  

2008 ◽  
Vol 371 (1) ◽  
pp. 163-167 ◽  
Author(s):  
Ji-Min Sung ◽  
Hee-Jung Cho ◽  
Hee Yi ◽  
Chi-Ho Lee ◽  
Hye-Sun Kim ◽  
...  

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