scholarly journals The First Characterization of a Novel Stem Cell Population and the Temporal Relationship with Satellite Cells in Human Skeletal Muscle

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Nelson Ian Saddler ◽  
Josh Nederveen ◽  
Tim Snijders ◽  
Sophie Joanisse ◽  
Jeff Baker ◽  
...  
2008 ◽  
Vol 40 (Supplement) ◽  
pp. S33
Author(s):  
Marni D. Boppart ◽  
Jianming Liu ◽  
Nicole M. Alexander ◽  
Stephen J. Kaufman

2012 ◽  
Vol 3 (1) ◽  
pp. 8-18 ◽  
Author(s):  
Hao Long ◽  
Shulin Zhang ◽  
Chunqi Liu ◽  
Jianlin Shi ◽  
Liyang Tao ◽  
...  

2011 ◽  
Vol 10 (2) ◽  
pp. 182
Author(s):  
O.G. Ivanovski ◽  
S.K. Saidi ◽  
S.O. Stavridis ◽  
S.A. Dohcev ◽  
O.L. Stankov ◽  
...  

2019 ◽  
Vol 15 (4) ◽  
pp. 519-529 ◽  
Author(s):  
Cosmin Andrei Cismaru ◽  
Olga Soritau ◽  
Ancuta - Maria Jurj ◽  
Raduly Lajos ◽  
Bogdan Pop ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Giovanna Rigillo ◽  
Valentina Basile ◽  
Silvia Belluti ◽  
Mirko Ronzio ◽  
Elisabetta Sauta ◽  
...  

AbstractThe transcription factor NF-Y promotes cell proliferation and its activity often declines during differentiation through the regulation of NF-YA, the DNA binding subunit of the complex. In stem cell compartments, the shorter NF-YA splice variant is abundantly expressed and sustains their expansion. Here, we report that satellite cells, the stem cell population of adult skeletal muscle necessary for its growth and regeneration, express uniquely the longer NF-YA isoform, majorly associated with cell differentiation. Through the generation of a conditional knock out mouse model that selectively deletes the NF-YA gene in satellite cells, we demonstrate that NF-YA expression is fundamental to preserve the pool of muscle stem cells and ensures robust regenerative response to muscle injury. In vivo and ex vivo, satellite cells that survive to NF-YA loss exit the quiescence and are rapidly committed to early differentiation, despite delayed in the progression towards later states. In vitro results demonstrate that NF-YA-depleted muscle stem cells accumulate DNA damage and cannot properly differentiate. These data highlight a new scenario in stem cell biology for NF-Y activity, which is required for efficient myogenic differentiation.


2008 ◽  
Vol 17 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Sanjleena Singh ◽  
Ben J. Jones ◽  
Ross Crawford ◽  
Yin Xiao

Stem Cells ◽  
2014 ◽  
Vol 32 (6) ◽  
pp. 1564-1577 ◽  
Author(s):  
M. Mamunur Rahman ◽  
Mallika Ghosh ◽  
Jaganathan Subramani ◽  
Guo-Hua Fong ◽  
Morgan E. Carlson ◽  
...  

Stem Cells ◽  
2006 ◽  
Vol 24 (12) ◽  
pp. 2840-2850 ◽  
Author(s):  
Maria Beatriz Herrera ◽  
Stefania Bruno ◽  
Stefano Buttiglieri ◽  
Ciro Tetta ◽  
Stefano Gatti ◽  
...  

2019 ◽  
Vol 21 (1) ◽  
pp. 31-46 ◽  
Author(s):  
Lucyene Miguita ◽  
Maria Cristina Zindel Deboni ◽  
Paul Sharpe ◽  
Andrea Mantesso

2008 ◽  
Vol 371 (1) ◽  
pp. 163-167 ◽  
Author(s):  
Ji-Min Sung ◽  
Hee-Jung Cho ◽  
Hee Yi ◽  
Chi-Ho Lee ◽  
Hye-Sun Kim ◽  
...  

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