Preparative, mechanistic and tautomeric investigation of 1-phenyl and 1-methyl derivative of 3-methyl-5-pyrazolone

2021 ◽  
Vol 133 (2) ◽  
Author(s):  
Hossein Fakhraian ◽  
Yaser Nafari
Keyword(s):  
Methyl Derivative

6,11-Dihydrodibenzo[b,e]thiepin-11-yl 3-quinuclidinyl ethers: New potential intidepressants and antihistamine agents

1988 ◽  
Vol 53 (8) ◽  
pp. 1806-1811 ◽  
Author(s):  
Zdeněk Polívka ◽  
Jan Metyš ◽  
Miroslav Protiva
Keyword(s):  
Methyl Derivative ◽  
Antihistamine Activity ◽  
Antidepressant Agent ◽  
Anticataleptic Activity

Reactions of 11-chloro-6,11-dihydrodibenzo[b,e]thiepin and its 2-methyl derivative, and further of the methanesulfonates of 2-chloro- and 2-bromo-6,11-dihydrodibenzo[b,e]thiepin-11-ol with 3-quinuclidinol afforded the title ethers I-IV. The 2-methyl compound II (VÚFB-17 088) showed significant antihistamine activity and the 2-chloro compound III (VÚFB-17 089), having antireserpine and anticataleptic activity, proved a potential antidepressant agent.

scholarly journals Heterogeneously‐catalyzed aerobic oxidation of methane to a methyl derivative

2021 ◽  
Author(s):  
Jeroen A. van Bokhoven ◽  
Andrea N. Blankenship ◽  
Manoj Ravi ◽  
Mark A. Newton
Keyword(s):  
Aerobic Oxidation ◽  
Methyl Derivative ◽  
Oxidation Of Methane

Langmuir Monolayers ofp-(5‘-m-Terphenylyl)benzoic Acid and Its 2‘-Methyl Derivative at the Water/Air Interface

Langmuir ◽  
1996 ◽  
Vol 12 (20) ◽  
pp. 4966-4968 ◽  
Author(s):  
Jan Czapkiewicz ◽  
Patrycja Dynarowicz ◽  
Piotr Milart
Keyword(s):  
Benzoic Acid ◽  
Langmuir Monolayers ◽  
Methyl Derivative ◽  
Air Interface

Synthesis and properties of azuleno[2,1-a]-3-8-methano[ 10 ] annulene and its 2-methyl derivative

1992 ◽  
Vol 33 (20) ◽  
pp. 2825-2828 ◽  
Author(s):  
Shigeyasu Kuroda ◽  
Jun-ichi Yazaki ◽  
Sunao Maeda ◽  
Kazuo Yamazaki ◽  
Masaki Yamada ◽  
...  
Keyword(s):  
Methyl Derivative

ChemInform Abstract: CONVERSION OF GUANOSINE INTO ITS N2-METHYL DERIVATIVE

1977 ◽  
Vol 8 (46) ◽  
pp. no-no
Author(s):  
P. K. BRIDSON ◽  
W. MARKIEWICZ ◽  
C. B. REESE
Keyword(s):  
Methyl Derivative

ChemInform Abstract: S-ALKYLATION OF 2-THIOXO-2,3-DIHYDROIMIDAZOLE AND ITS 1-METHYL DERIVATIVE UNDER PHASE-TRANSFER CONDITIONS

1977 ◽  
Vol 8 (31) ◽  
pp. no-no
Author(s):  
P. HASSANALY ◽  
H. J. M. DOU ◽  
J. METZGER ◽  
G. ASSEF ◽  
J. KISTER
Keyword(s):  
Phase Transfer ◽  
Methyl Derivative

Structure of 4,4-Bisphenylsulfonyl-N,N-dimethylbutylamine: Interplay of Intramolecular C–H···N, C–H···O=S, and ?···? Interactions

2009 ◽  
Vol 62 (9) ◽  
pp. 1062 ◽  
Author(s):  
Jiong Ran ◽  
Ming Wah Wong
Keyword(s):  
Molecular Structure ◽  
Hydrogen Bond ◽  
Significant Interaction ◽  
Chemical Shifts ◽  
Intramolecular Interactions ◽  
Methyl Derivative ◽  
Polar Medium ◽  
Conformational Properties ◽  
Density Analysis ◽  
Experimental Findings

Conformations of 4,4-bisphenylsulfonyl-N,N-dimethylbutylamine (BSDBA) were examined by ab initio calculations. Intramolecular C–H···N, C–H···O, and π···π interactions are found to play an important role in governing the conformational properties. This finding is supported by charge density analysis based on the theory of atoms in molecules. The calculated molecular structure and 1H chemical shifts of the methyl derivative (BSTBA) are in excellent agreement with experimental findings. The intramolecular C–H···N hydrogen bond in BSDBA is estimated to have a significant interaction energy of 25 kJ mol–1. The sulfonyl oxygens in BSDBA interact readily with neighbouring methylene, methyl and phenyl hydrogens via C–H···O=S hydrogen bonds. In agreement with experiment, solvent effect calculations indicate that these weaker intramolecular interactions prevail in an aprotic polar medium.

Sign in / Sign up

Export Citation Format

Share Document