Role of Automated Urine Flow Cytometry for the Diagnosis of Urinary Tract Infection in Children

2018 ◽  
Vol 85 (11) ◽  
pp. 961-962
Author(s):  
Om P. Mishra ◽  
Rajniti Prasad
2015 ◽  
Vol 448 ◽  
pp. 86-90 ◽  
Author(s):  
N. Geerts ◽  
A.R. Jansz ◽  
K.J.M. Boonen ◽  
R.P.W.F. Wijn ◽  
E.L. Koldewijn ◽  
...  

2019 ◽  
Vol 8 (50) ◽  
pp. 3805-3812
Author(s):  
Md. Shamshir Alam ◽  
Komal Rana ◽  
Shweta Bhardwaj ◽  
Jagatheesh Kaliaperumal ◽  
Md. Sarfaraj Hussain ◽  
...  

2022 ◽  
Vol 23 (2) ◽  
pp. 870
Author(s):  
Anna Kawalec ◽  
Danuta Zwolińska

The microbiome of the urinary tract plays a significant role in maintaining health through the impact on bladder homeostasis. Urobiome is of great importance in maintaining the urothelial integrity and preventing urinary tract infection (UTI), as well as promoting local immune function. Dysbiosis in this area has been linked to an increased risk of UTIs, nephrolithiasis, and dysfunction of the lower urinary tract. However, the number of studies in the pediatric population is limited, thus the characteristic of the urobiome in children, its role in a child’s health, and pediatric urologic diseases are not completely understood. This review aims to characterize the healthy urobiome in children, the role of dysbiosis in urinary tract infection, and to summarize the strategies to modification and reshape disease-prone microbiomes in pediatric patients with recurrent urinary tract infections.


1987 ◽  
Vol 137 (2) ◽  
pp. 342-344 ◽  
Author(s):  
Abdul J. Khan ◽  
Kusum Kumar ◽  
Hugh E. Evans

2017 ◽  
Vol 86 (3) ◽  
Author(s):  
Anna Sintsova ◽  
Sara Smith ◽  
Sargurunathan Subashchandrabose ◽  
Harry L. Mobley

ABSTRACTUrinary tract infection (UTI) is the second most common infection in humans, making it a global health priority. Nearly half of all women will experience a symptomatic UTI, with uropathogenicEscherichia coli(UPEC) being the major causative agent of the infection. Although there has been extensive research on UPEC virulence determinants, the importance of host-specific metabolism remains understudied. We report here that UPEC upregulates the expression of ethanolamine utilization genes during uncomplicated UTIs in humans. We further show that UPEC ethanolamine metabolism is required for effective bladder colonization in the mouse model of ascending UTI and is dispensable for bladder colonization in an immunocompromised mouse model of UTI. We demonstrate that although ethanolamine metabolism mutants do not show increased susceptibility to antimicrobial responses of neutrophils, this metabolic pathway is important for surviving the innate immune system during UTI. This study reveals a novel aspect of UPEC metabolism in the host and provides evidence for an underappreciated link between bacterial metabolism and the host immune response.


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