Validated RP-HPLC Method for Simultaneous Determination of Tocopherols and Tocotrienols in Whole Grain Barley Using Matrix Solid-Phase Dispersion

2014 ◽  
Vol 8 (2) ◽  
pp. 392-400 ◽  
Author(s):  
Emmanouil D. Tsochatzis ◽  
Roxani Tzimou-Tsitouridou
Keyword(s):  
Simultaneous Determination ◽  
Solid Phase ◽  
Hplc Method ◽  
Whole Grain ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Rp Hplc

scholarly journals New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1312
Author(s):  
Luyi Jiang ◽  
Jie Wang ◽  
Huan Zhang ◽  
Caijing Liu ◽  
Yiping Tang ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
High Performance ◽  
Solid Phase ◽  
Hplc Method ◽  
Factors Affecting ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Quantitative Determination Method ◽  
Grinding Time

In this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C18 and silica gel were investigated. The strategy included two steps: Extraction and determination. Wasted crab shells were used as an alternative adsorbent and ionic liquid was used as an alternative solvent in the first step. Factors affecting extraction efficiency were optimized: A sample/adsorbent ratio of 2:1, a grinding time of 3 min, a vortex time of 3 min, and ionic liquid ([Domim]HSO4, 250 mM) was used as eluent in the VS-MSPD procedure. As a result, the established method provided satisfactory linearity (R > 0.999), good accuracy and high reproducibility (RSD < 4.60%), and it exhibited the advantages of smaller sample amounts, shorter extraction time, less volume of elution solvent, and was much more environmental-friendly when compared with other conventional methods.

scholarly journals Simultaneous determination of fumonisins B1 and B2 in different types of maize by matrix solid phase dispersion and HPLC-MS/MS

2017 ◽  
Vol 233 ◽  
pp. 11-19 ◽  
Author(s):  
Gabriel Barros de Oliveira ◽  
Carolyne Menezes de Castro Gomes Vieira ◽  
Ricardo Mathias Orlando ◽  
Adriana Ferreira Faria
Keyword(s):  
Simultaneous Determination ◽  
Solid Phase ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Different Types ◽  
Fumonisins B1 And B2

scholarly journals Simultaneous determination of 11 preservatives in cosmetics and pharmaceuticals by matrix solid-phase dispersion coupled with gas chromatography

2020 ◽  
Vol 32 (3) ◽  
pp. 203-209
Author(s):  
Yun-feng Liu ◽  
Jia-ling Zhang ◽  
Xue-fei Nie ◽  
Ping Zhang ◽  
Xiao-qing Yan ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Simultaneous Determination ◽  
Matrix Effects ◽  
Solid Phase ◽  
Correlation Coefficients ◽  
Sample Pretreatment ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Flame Ionization

A convenient method was developed for simultaneous determination of 11 preservatives in cosmetics and pharmaceuticals. Matrix solid-phase dispersion had been optimized as the sample pretreatment technology, using Florisil as a dispersant, anhydrous sodium sulfate as a dehydrant, formic acid as an additive, and n-hexane and ethyl acetate as eluents successively, and followed by gas chromatography–flame ionization detection on a TR-5 capillary column. Experimental results showed that 11 preservatives were baseline separated within 22 min. Good linearities were observed in the concentration range of 0.53–250 μg/mL for all analytes, and there were also minor differences. All correlation coefficients (r) were more than 0.995. The average recoveries at 3 levels of spiked samples ranged from 80% to 124% with 0.9–12% intra-day RSD and 1.8–12% inter-day RSD. The limits of detection were less than 0.18 μg/mL for all analytes. Besides, there was no obvious matrix effect on the analytes. The conclusion was that the developed method was simple, cheap, accurate, precise, and environment-friendly, in addition to existing little matrix effects. It could be recommended to determine 11 preservatives individually or in any their combinations to not only in liquid and gel cosmetics but also in liquid medicine and ointment.

Sign in / Sign up

Export Citation Format

Share Document