Protective effect of hydrogen sulfide against cold restraint stress-induced gastric mucosal injury in rats

2013 ◽  
Vol 36 (12) ◽  
pp. 1507-1515 ◽  
Author(s):  
Esam M. Aboubakr ◽  
Ashraf Taye ◽  
Mohamed A. El-Moselhy ◽  
Magdy K. Hassan
Keyword(s):  
Hydrogen Sulfide ◽  
Protective Effect ◽  
Restraint Stress ◽  
Mucosal Injury ◽  
Gastric Mucosal Injury ◽  
Cold Restraint Stress ◽  
Cold Restraint

scholarly journals Gastroprotective effects of nebivolol and simvastatin against cold restraint stress-induced gastric ulcer in rats

2020 ◽  
Vol 53 (3) ◽  
pp. 301-312
Author(s):  
Samaa Samir Kamar ◽  
Noha Samir Abdel Latif ◽  
Mohamed Fathi Mohamed Elrefai ◽  
Shaimaa Nasr Amin
Keyword(s):  
Gastric Ulcer ◽  
Restraint Stress ◽  
Cold Restraint Stress ◽  
Cold Restraint

scholarly journals EFFECT OF SYNTHETIC ACYCLIC POLYISOPRENOIDS ON THE COLD-RESTRAINT STRESS INDUCED GASTRIC ULCER IN RATS

1983 ◽  
Vol 33 (3) ◽  
pp. 549-556
Author(s):  
Manabu MURAKAMI ◽  
Kiyoshi OKETANI ◽  
Hideaki FUJISAKI ◽  
Tsuneo WAKABAYASHI ◽  
Yuichi INAI ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Restraint Stress ◽  
Cold Restraint Stress ◽  
Cold Restraint

Cold-restraint stress increases rat fecal pellet output and colonic transit

1990 ◽  
Vol 258 (3) ◽  
pp. G329-G337 ◽  
Author(s):  
F. C. Barone ◽  
J. F. Deegan ◽  
W. J. Price ◽  
P. J. Fowler ◽  
J. D. Fondacaro ◽  
...  
Keyword(s):  
Restraint Stress ◽  
Fecal Pellet ◽  
Gastrointestinal Transit ◽  
Colonic Transit ◽  
Gastric Ulcers ◽  
Small Intestinal Transit ◽  
Fluid Content ◽  
Fecal Output ◽  
Cold Restraint Stress ◽  
Cold Restraint

Increased fecal pellet output that occurs during cold-restraint stress (CRS) was evaluated systematically. Free-feeding rats, which exhibit a reduced occurrence of gastric ulcers under these conditions, were studied. CRS significantly increased fecal pellet production and fluid content. However, the fecal output produced during CRS was not associated with increased gut secretory activity or somatic motor activity associated with cold restraint and did not occur in anesthetized animals. Cold and restraint stress were additive in producing increased fecal output. Significant dose-related decreases in fecal output were produced by drugs that decrease gut transit (i.e., B-HT 920, clonidine, Lomotil, loperamide, and lidamidine). Anticholinergic-antisecretory drugs, antidepressants, and tranquilizers had little effect on fecal output or fluid content. Changes in gastrointestinal transit did not contribute to the increased fecal output during CRS. Transit in the lower small intestine was not altered, but the cecum tended to empty more contents into the large intestine during CRS. Colonic transit was dramatically affected by CRS, which eliminated retrograde transit and produced the evacuation of the majority of colonic contents. The increased colonic transit produced by CRS was decreased in a dose-related fashion by hexamethonium, nifedipine, loperamide, and B-HT 920. In several time-response and drug-inhibition studies during CRS, both fecal pellet output and colonic transit were affected similarly. These data indicate that CRS appears to change central nervous system output to the colon and that it alters colonic smooth muscle motility in a manner that facilitates colonic transit and evacuation. Small intestinal transit is not involved in this phenomenon and is regulated differently during CRS.

scholarly journals Protective effect of extract of Agkistrodon blomhof fii on acute gastric mucosal injury induced by ischemia-reperfusion in rats.

1996 ◽  
Vol 71 ◽  
pp. 202
Author(s):  
Tadao Itoh ◽  
Kouichirou Wada ◽  
Yoshinori Kamisaki ◽  
Masayuki Kitano ◽  
Yosuke Kishimoto ◽  
...  
Keyword(s):  
Protective Effect ◽  
Ischemia Reperfusion ◽  
Mucosal Injury ◽  
Gastric Mucosal Injury

scholarly journals Protective effect of dietary nitrate on stress-induced gastric mucosal injury via enhancing blood perfusion in Mongolian gerbils

2020 ◽  
Vol 133 (17) ◽  
pp. 2141-2142
Author(s):  
Bao-Xing Pang ◽  
Ling-Xue Bu ◽  
Mu-Yun Jia ◽  
Li-Qiang Chen ◽  
Kai Song ◽  
...  
Keyword(s):  
Protective Effect ◽  
Blood Perfusion ◽  
Mucosal Injury ◽  
Gastric Mucosal Injury ◽  
Mongolian Gerbils ◽  
Dietary Nitrate
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