Relative palatability and efficacy of brodifacoum-25D conservation rodenticide pellets for mouse eradication on Midway Atoll

Invasive mice (Mus spp.) can negatively impact island species and ecosystems. Because fewer island rodent eradications have been attempted for mice compared to rats (Rattus spp.), less is known about efficacy and palatability of rodenticide baits for mouse eradications. We performed a series of bait acceptance and efficacy cage trials using a standard formulation of brodifacoum-based rodenticide on wild-caught mice from Sand Island, Midway Atoll, to help inform a proposed eradication there. Mice were offered ad libitum brodifacoum pellets along with various alternative food sources, and a “no choice” treatment group received only bait pellets. Mortality in the no choice trial was 100%; however, when offered alternative foods, mice preferred the alternative diets to the bait, leading to low mortality (40%). Because there was concern that the bittering agent Bitrex® in the formulation may have reduced palatability, we conducted a subsequent trial comparing brodifacoum bait with and without Bitrex. Mortality in the with-Bitrex treatment group was slightly higher, indicating that the bittering agent was not likely responsible for low efficacy. Laboratory trials cannot account for the numerous environmental and behavioral factors that influence bait acceptance nor replicate the true availability of alternative food sources in the environment, so low efficacy results from these trials should be interpreted cautiously and not necessarily as a measure of the likelihood of success or failure of a proposed eradication.

Behavioral Factors Influencing Stock Investment Decision of Individuals

Purpose: The purpose of this study is to identify the behavioral factors influencing individual investors’ decisions and to analyze the relationship between these factors and investment decision performance. Design/Methodology/Approach: The tested variables were: Anchoring bias, Gambler’s Fallacy, Overconfidence bias, Availability and Representativeness bias from heuristics factor, Mental Accounting, Loss and Regret Aversion from prospect factor, and Market variables and Herding factors. The study employed exploratory and confirmatory factor analysis. In addition, structural equation modeling is applied for the testing of the hypotheses. Findings: Prospect behavioral factor is seen to have negative correlation to investment performance. Herding, Market variables and Heuristic (including overconfidence and anchoring bias) are found to have positive correlation to investment performance. Implications: To cope with intense competition among the competitors in Nepali stock market, this study provides strong evidence herding and heuristic approach that have positive indication to investment performance

Evaluating the Effect of Electroconvulsive Shock and Duloxetine Combination Therapy on Behavioral, Cardiovascular, and Brain Oxidative Stress Markers in the Rats

Background: Electroconvulsive Therapy (ECT) as a well-established and effective therapeutic approach for the treatment of various psychiatric disorders is an excellent option to treat the major depressive disorder (MDD). The goal of this experimental study was to determine the possible sides effects of electroconvulsive shock (ECS) and duloxetine, a serotonin-norepinephrine Reuptake Inhibitors (SNRIs), and evaluate the safety of this therapeutic approach on behavioral factors, cardiovascular function, and brain oxidative stress markers on mice. Materials and Methods: Animals were divided into different groups receiving either ECS or different doses (10, 20, 40, 80, or 120 mg) of duloxetine alone or together. We evaluated the behavioral factors associated with administration of ECS with or without duloxetine. In addition, we monitored the ECGs (electrocardiogram) of animals prior to and after the experiment and also evaluated the oxidative stress markers including TAC, MDA, and GSH mice’s brains. Results: We did not detect any significant differences in terms of heart rate, RR interval, PR interval, QT, or corrected QT (QTc) between groups that received different doses of duloxetine in combination with ECS compare to the control group. Our findings suggest that while administration of ECS solely increased the oxidative stress markers and decreased the antioxidant capacity of the brain, a combination of duloxetine and ECS at certain doses alleviates the oxidative stress condition and increases the antioxidant capacity of the brain. Conclusion: Overall, this study suggests that the combination of ECS and duloxetine is safe and considerable for further studies on human subjects.

BEHAVIORAL FACTORS OF INTERNAL AUDITORS AND ENTERPRISE RISK MANAGEMENT EFFECTIVENESS ASSESSMENT OF MALAYSIAN STATUTORY BODIES

This study used the theory of planned behavior to examine the relationship between internal auditors’ behavioral factors and intention to evaluate enterprise risk management (ERM) effectiveness of Malaysian statutory bodies. Unlike prior literature, this study also included a test on individual attitude towards risk in addition to attitude towards behavior, subjective norms, and perceived behavioral control. Analysis on 108 received responses showed that subjective norms and perceived behavioral control had positive relationships with the intention to assess ERM effectiveness. Nevertheless, the influence of attitude was not substantiated. The results imply that attitude is not an important factor when individuals do not have total process ownership. Managers of statutory bodies and heads of internal audit departments need to shape internal auditor behavior by instituting social and administrative norms and instilling a positive perception about the ability to perform tasks within the organization. This study also shows that individuals have no total ownership in a process, thus focusing efforts on shaping individual attitude is not practical. This issue is critical because successful ERM implementation depends on internal auditors’ intention to evaluate its effectiveness. An effective ERM can reduce the risks of waste, inefficiencies, corruption, malpractices, and public–private partnerships associated with the public sector.

Gender differences in life expectancy of the population of Tatarstan

During the spread of coronavirus infection around the world, much attention is being paid to study of excessive mortality of the population, which has impact on life expectancy. Achieving the goals set by the Government of the Russian Federation to achieve life expectancy of 78 years by 2030 depends on many factors, including reduction of gender differences in life expectancy and excess mortality of the male population from various classes of causes. But in 2020 there was a turning point which led to a decrease in life expectancy to the level of 2014. This fact requires a more detailed study of the negative consequences of gender differences in this demographic indicator. The data of Rosstat and the sociological study "Demographic well-being of Tatarstan" conducted by the Family and Demography Center of the Tatarstan Academy of Sciences served as an information resource. The purpose of the article is to identify the main social consequences of gender differences in life expectancy. The main socio-cultural and behavioral factors of male mortality are highlighted. Among the behavioral factors that are closest to explaining the high mortality of Russian men is alcohol consumption, which is considered as an optional phenomenon of suicide. The direct expression (consequence) of a certain behavior is the most characteristic tendency of men to neglect their own health. In order to change the situation, only the state policy on development of measures aimed at creating conditions for raising the life expectancy is not sufficient, it is also necessary to change the consciousness of men to form motivation for the need to preserve and strengthen health.