Plastic Changes in Striatal Fast-Spiking Interneurons Following Hemicerebellectomy and Environmental Enrichment

2011 ◽  
Vol 10 (3) ◽  
pp. 624-632 ◽  
Author(s):  
Paola De Bartolo ◽  
Francesca Gelfo ◽  
Lorena Burello ◽  
Andrea De Giorgio ◽  
Laura Petrosini ◽  
...  
2018 ◽  
Author(s):  
E. Mae Guthman ◽  
Ming Ma ◽  
Philip Chu ◽  
Serapio M. Baca ◽  
Diego Restrepo ◽  
...  

AbstractThe basolateral amygdala (BLA) plays a vital role in associating specific sensory stimuli with salient valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode this integrated sensory-valence information; however, local BLA inhibitory interneurons (INs) gate the plasticity of the PNs via feed forward inhibition (FFI). Despite extensive literature implicating parvalbumin expressing (PV+) INs in FFI in cortex and hippocampus, prior anatomical experiments in BLA implicate somatostatin expressing (Sst+) INs in BLA. In the present study, we combined patch clamp electrophysiology with chemogenetics, unsupervised cluster analysis, and predictive modeling and found that a previously unreported subpopulation of fast-spiking Sst+ INs mediate BLA FFI and gate plasticity.


2019 ◽  
Vol 222 (10) ◽  
pp. jeb200402 ◽  
Author(s):  
Stephanie Fong ◽  
Séverine D. Buechel ◽  
Annika Boussard ◽  
Alexander Kotrschal ◽  
Niclas Kolm

2009 ◽  
Author(s):  
Kathy May Tran ◽  
Madeleine Broder ◽  
Suzannah Luft ◽  
Michael L. Schwartz ◽  
Karen Muller Smith ◽  
...  

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