Feasibility and efficacy of gentamicin for treating neonatal sepsis in community-based settings: a systematic review

2016 ◽  
Vol 12 (4) ◽  
pp. 408-414 ◽  
Author(s):  
Nishant Jaiswal ◽  
Meenu Singh ◽  
Ritika Kondel ◽  
Navjot Kaur ◽  
Kiran K. Thumburu ◽  
...  
2018 ◽  
Vol 16 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Gambhir Shrestha ◽  
Rashmi Mulmi ◽  
Nibaran Joshi ◽  
Parashu Ram Shrestha

Nepal lacks adequate data on the prevalence of sepsis and Possible Severe Bacterial Infection (PSBI) among neonates. Thus, this systematic review was designed to estimate the prevalence of neonatal sepsis and PSBI status in Nepal. We searched PubMed and Nepal Journal Online for relevant studies on PSBI and neonatal sepsis published from 2006 to 2016. The eligibility criteria included those studies done in Nepal, evaluating the prevalence of PSBI/neonatal sepsis with denominators as the population at risk that is either total live births or total cases evaluated. Altogether, four studies met the review criteria, out of which three were hospital-based and one community-based. There is a vast difference in prevalence rate between hospital-based (2-4%) and community-based (9%) studies. Two studies used haematological scoring system and blood culture to base their diagnosis; one used signs and symptoms for PSBI while the other did not mention the diagnostic criteria. This systematic review suggests that though neonatal sepsis poses a big problem, it lacks a significant number of related studies. There is a need to conduct a nationwide survey on the prevalence of sepsis and PSBI among neonates, which will help to develop health policy.


2007 ◽  
Vol 10 (1) ◽  
pp. 11-26 ◽  
Author(s):  
T. Larsen ◽  
S. Kumar ◽  
K. Grimmer ◽  
A. Potter ◽  
T. Farquharson ◽  
...  

2021 ◽  
Author(s):  
Aline Uhirwa Bjerkhaug ◽  
Hildegunn Norbakken Granslo ◽  
Claus Klingenberg

2021 ◽  
Author(s):  
Emma Persad ◽  
Kerstin Jost ◽  
Antoine Honoré ◽  
David Forsberg ◽  
Karen Coste ◽  
...  

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Mei Chan ◽  
Melinda Gray ◽  
Christine Burns ◽  
Louisa Owens ◽  
Susan Woolfenden ◽  
...  

Abstract Objective We conducted a systematic review and meta-analysis to determine the effectiveness of comprehensive community-based interventions with ≥ 2 components in improving asthma outcomes in children. Methods A systematic search of Medline, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Excerpta Medica Database (EMBASE), Cochrane Library and hand search of reference collections were conducted to identify any research articles published in English between 2000 and 2019. All studies reporting community-based asthma interventions with ≥ 2 components (e.g., asthma self-management education, home environmental assessment or care coordination etc.) for children aged ≤ 18 years were included. Meta-analyses were performed using random-effects model to estimate pooled odds ratio (OR) with 95% confidence intervals (CIs). Results Of the 2352 studies identified, 21 studies were included in the final analysis: 19 pre-post interventions, one randomised controlled trial (RCT) and one retrospective study. Comprehensive asthma programs with multicomponent interventions were associated with significant reduction in asthma-related Emergency Department (ED) visits (OR = 0.26; 95% CI 0.20–0.35), hospitalizations (OR = 0.24; 95% CI 0.15–0.38), number of days (mean difference = − 2.58; 95% CI − 3.00 to − 2.17) and nights with asthma symptoms (mean difference = − 2.14; 95% CI − 2.94 to − 1.34), use of short-acting asthma medications/bronchodilators (BD) (OR = 0.28; 95% CI 0.16–0.51), and increase use of asthma action plan (AAP) (OR = 8.87; 95% CI 3.85–20.45). Conclusion Community-based asthma care using more comprehensive approaches may improve childhood asthma management and reduce asthma related health care utilization.


Author(s):  
Aoife Watson ◽  
Donna McConnell ◽  
Vivien Coates

Abstract Aim To determine which community-based interventions are most effective at reducing unscheduled hospital care for hypoglycaemic events in adults with diabetes. Methods Medline Ovid, CINAHL Plus and ProQuest Health and Medical Collection were searched using both key search terms and medical subject heading terms (MeSH) to identify potentially relevant studies. Eligible studies were those that involved a community-based intervention to reduce unscheduled admissions in adults with diabetes. Papers were initially screened by the primary researcher and then a secondary reviewer. Relevant data were then extracted from papers that met the inclusion criteria. Results The search produced 2226 results, with 1360 duplicates. Of the remaining 866 papers, 198 were deemed appropriate based on titles, 90 were excluded following abstract review. A total of 108 full papers were screened with 19 full papers included in the review. The sample size of the 19 papers ranged from n = 25 to n = 104,000. The average ages within the studies ranged from 41 to 74 years with females comprising 57% of the participants. The following community-based interventions were identified that explored reducing unscheduled hospital care in people with diabetes; telemedicine, education, integrated care pathways, enhanced primary care and care management teams. Conclusions This systematic review shows that a range of community-based interventions, requiring different levels of infrastructure, are effective in reducing unscheduled hospital care for hypoglycaemia in people with diabetes. Investment in effective community-based interventions such as integrated care and patient education must be a priority to shift the balance of care from secondary to primary care, thereby reducing hospital admissions.


BMJ Open ◽  
2015 ◽  
Vol 5 (4) ◽  
pp. e007210-e007210 ◽  
Author(s):  
L. Amiri Farahani ◽  
M. Asadi-Lari ◽  
E. Mohammadi ◽  
S. Parvizy ◽  
A. A. Haghdoost ◽  
...  

2018 ◽  
Vol 6 (3) ◽  
pp. 223-230 ◽  
Author(s):  
Carolin Fleischmann-Struzek ◽  
David M Goldfarb ◽  
Peter Schlattmann ◽  
Luregn J Schlapbach ◽  
Konrad Reinhart ◽  
...  

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