Cellular activation of selected signaling proteins through resistance training—a training methodological perspective

2017 ◽  
Vol 48 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Nico Nitzsche ◽  
Tilo Neuendorf ◽  
Sebastian Gehlert ◽  
Michael Fröhlich ◽  
Henry Schulz
Keyword(s):  
Resistance Training ◽  
Signaling Proteins ◽  
Cellular Activation ◽  
Methodological Perspective

mTOR signaling response to resistance exercise is altered by chronic resistance training and detraining in skeletal muscle

2013 ◽  
Vol 114 (7) ◽  
pp. 934-940 ◽  
Author(s):  
Riki Ogasawara ◽  
Koji Kobayashi ◽  
Arata Tsutaki ◽  
Kihyuk Lee ◽  
Takashi Abe ◽  
...  
Keyword(s):  
Resistance Training ◽  
Resistance Exercise ◽  
Intracellular Signaling ◽  
Gastrocnemius Muscle ◽  
Male Rats ◽  
Exercise Session ◽  
Signaling Proteins ◽  
Signaling Mechanisms ◽  
Exercise Induced ◽  
Training And Detraining

Resistance training-induced muscle anabolism and subsequent hypertrophy occur most rapidly during the early phase of training and become progressively slower over time. Currently, little is known about the intracellular signaling mechanisms underlying changes in the sensitivity of muscles to training stimuli. We investigated the changes in the exercise-induced phosphorylation of hypertrophic signaling proteins during chronic resistance training and subsequent detraining. Male rats were divided into four groups: 1 bout (1B), 12 bouts (12B), 18 bouts (18B), and detraining (DT). In the DT group, rats were subjected to 12 exercise sessions, detrained for 12 days, and then were subjected to 1 exercise session before being killed. Isometric training consisted of maximum isometric contraction, which was produced by percutaneous electrical stimulation of the gastrocnemius muscle every other day. Muscles were removed 24 h after the final exercise session. Levels of total and phosphorylated p70S6K, 4E-BP1, rpS6, and p90RSK levels were measured, and phosphorylation of p70S6K, rpS6, and p90RSK was elevated in the 1B group compared with control muscle (CON) after acute resistance exercise, whereas repeated bouts of exercise suppressed those phosphorylation in both 12B and 18B groups. Interestingly, these phosphorylation levels were restored after 12 days of detraining in the DT group. On the contrary, phosphorylation of 4E-BP1 was not altered with chronic training and detraining, indicating that, with chronic resistance training, anabolic signaling becomes less sensitive to resistance exercise stimuli but is restored after a short detraining period.

The response of insulin signaling proteins IRS1 and PTP-1B to endurance, HIIT and resistance training in rats with experimental diabetes

2019 ◽  
Vol 34 (3) ◽  
pp. e229-e233
Author(s):  
R. Soori ◽  
A.A. Ravasi ◽  
S. Choobineh ◽  
M. Motiee ◽  
F. Sohrabi ◽  
...  
Keyword(s):  
Resistance Training ◽  
Insulin Signaling ◽  
Experimental Diabetes ◽  
Signaling Proteins ◽  
Ptp 1B

Training for Performance: Insights From Molecular Biology

2006 ◽  
Vol 1 (3) ◽  
pp. 284-292 ◽  
Author(s):  
Vernon G. Coffey ◽  
John A. Hawley
Keyword(s):  
Resistance Training ◽  
Molecular Biology ◽  
Molecular Basis ◽  
Signaling Proteins ◽  
Training Adaptation

In this commentary the authors discuss the molecular basis of the training adaptation and review the role of several key signaling proteins important in the adaptation to endurance and resistance training.

Fortified Yogurt a Plus During Resistance Training

2007 ◽  
Vol 2 (12) ◽  
pp. 21
Author(s):  
FRAN LOWRY
Keyword(s):  
Resistance Training

Progression and Resistance Training

2005 ◽  
Author(s):  
William J. Kraemer ◽  
Nicholas A. Ratamess ◽  
Deborah Young ◽  
Barbara Ainsworth
Keyword(s):  
Resistance Training
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