In order to make a research on all the factors which influence the dissolution rate of the rock salt, this article study on how the temperature, concentration of the rock salt solution, the dissolution obliquity, and the velocity influence the rock salt dissolution rate. The experiment shows that, all the factors make strong influences on the dissolution rate as follow: ⑴ when the obliquity is 180°, the dissolution rate is the largest, and the 0°is the smallest. The dissolution rate increases with the increasing of the obliquity. ⑵ the dissolution rate increases with the concentration to the largest and then insoluble in saturation.⑶ the dissolution rate increases with the temperature increase. ⑷At first, the dissolution increases with the velocity of the flow, then decreases to stabilize.⑸ This article also integrates the relationship between the temperature, obliquity, velocity and the dissolution rate, and the research result will play a key role in the production of cavity and the numerical simulation in the production procedure.