The present work aimed mainly at investigating the influence of tissue structure on dehydration characteristics of zucchini and carrot. Microwave power levels of 100, 350, 550 and 750 W used to dehydrate the samples with thicknesses of 3, 5, 7 and 9 mm. The results showed that moisture removal from the slices occurred in a short accelerating period at the process beginning followed by a falling rate period. The moisture diffusivity increased with both increasing microwave power and the samples thickness where the average values for zucchini and carrot slices changed from 1.17×10-8 to 9.42×10-8 and from 0.73×10-8 to 5.51×10-8 m2 s-1, respectively. The average activation energy for zucchini and carrot slices varied in the range of 1.22–1.68 and 1.57–1.84 W g-1, respectively and decreased with increasing samples thickness.