Early Radiation-induced Leiomyosarcoma after Right Mastectomy in an 83-year old Woman

2020 ◽  
Vol 92 (5-6) ◽  
pp. 186-188
Author(s):  
Miltiadis Badagionis ◽  
S. Lainas ◽  
D. Sekadakis ◽  
V. Gkanis ◽  
P. Chortis ◽  
...  
Keyword(s):  
Radiation Induced ◽  
Early Radiation

scholarly journals Use of human lymphocyte G0 PCCs to detect intra- and inter-chromosomal aberrations for early radiation biodosimetry and retrospective assessment of radiation-induced effects

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216081 ◽  
Author(s):  
Terri L. Ryan ◽  
Antonio G. Pantelias ◽  
Georgia I. Terzoudi ◽  
Gabriel E. Pantelias ◽  
Adayabalam S. Balajee
Keyword(s):  
Chromosomal Aberrations ◽  
Human Lymphocyte ◽  
Retrospective Assessment ◽  
Radiation Induced ◽  
Early Radiation ◽  
Radiation Biodosimetry

Progressive behavioral changes during the maturation of rats with early radiation-induced hypoplasia of fascia dentata granule cells

1989 ◽  
Vol 11 (4) ◽  
pp. 385-393 ◽  
Author(s):  
G.Andrew Mickley ◽  
J.Leland Ferguson ◽  
Maureen A. Mulvihill ◽  
Thomas J. Nemeth
Keyword(s):  
Granule Cells ◽  
Behavioral Changes ◽  
Fascia Dentata ◽  
Radiation Induced ◽  
Early Radiation

scholarly journals Effect of ozone oxidative preconditioning in preventing early radiation-induced lung injury in rats

2013 ◽  
Vol 46 (9) ◽  
pp. 789-796 ◽  
Author(s):  
B.H. Bakkal ◽  
F.A. Gultekin ◽  
B. Guven ◽  
U.O. Turkcu ◽  
S. Bektas ◽  
...  
Keyword(s):  
Lung Injury ◽  
Radiation Induced ◽  
Early Radiation

scholarly journals Early Radiation-Induced Sarcoma in an Adolescent Treated for Relapsed Hodgkin Lymphoma with Nivolumab

Medicina ◽  
2020 ◽  
Vol 56 (4) ◽  
pp. 155
Author(s):  
Lukas Šalaševičius ◽  
Goda Elizabeta Vaitkevičienė ◽  
Ramunė Pasaulienė ◽  
Rosita Kiudelienė ◽  
Ernesta Ivanauskaitė-Didžiokienė ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Correct Diagnosis ◽  
Secondary Malignancy ◽  
Drug Resistant ◽  
Classic Hodgkin Lymphoma ◽  
Pet Ct ◽  
Radiation Induced ◽  
Early Radiation ◽  
Tumor Biopsies ◽  
Pet Ct Scan

Radiation-induced sarcoma (RIS) has been reported as a late secondary malignancy following radiotherapy for various types of cancer with a median latency of 10 years. We describe an early RIS that developed in an adolescent within three years of treatment (including PD-L1 check-point inhibitor Nivolumab) of a relapsed classic Hodgkin lymphoma (HL) and was diagnosed post-mortem. The patient died of the progressive RIS that was misleadingly assumed to be a resistant HL based on the positive PET/CT scan. Repetitive tumor biopsies are warranted in cases of aggressive and multi-drug resistant HL to validate imaging findings, ensure correct diagnosis and avoid overtreatment.

scholarly journals EP-1168 Early radiation induced changes in salivary glands in nasopharyngeal cancer patients after IMRT

2019 ◽  
Vol 133 ◽  
pp. S646
Author(s):  
W.V. Wu ◽  
M.T. Ying ◽  
D.L. Kwong ◽  
G.K. Wong ◽  
P. Khong
Keyword(s):  
Salivary Glands ◽  
Cancer Patients ◽  
Nasopharyngeal Cancer ◽  
Radiation Induced ◽  
Early Radiation ◽  
Induced Changes

Complications of radio- and radiochemotherapy in patients undergoing major salivary gland cancer surgery

2019 ◽  
Vol 73 (3) ◽  
pp. 26-31
Author(s):  
Izabela Kordzińska-Cisek ◽  
Ludmiła Grzybowska-Szatkowska
Keyword(s):  
Overall Survival ◽  
Salivary Gland ◽  
Subcutaneous Tissue ◽  
Tnm Classification ◽  
Healing Time ◽  
Salivary Gland Cancer ◽  
Major Salivary Gland ◽  
Radiation Induced ◽  
Early Radiation ◽  
Induced Reaction

Purpose: The aim of this retrospective study was to present the prevalence of early and late radiation-induced reaction and factors affecting its formation and severity in patients after adjuvant radio- or radiochemotherapy in salivary gland cancer. Material and methods: A total of 113 patients with early and 91 with late radiation-induced reaction, irradiated in 2006-2016 were enrolled in the study. The frequency of acute mucosal radiation-induced reaction, time of onset, intensity, healing time, as well as the incidence of late radiation-induced reaction from the skin and subcutaneous tissue were analyzed. Factors that could influence the development and intensity of reaction were identified. Results: Acute severity and the presence of late radiation-induced reaction do not affect overall survival. Dosage in the tumor bed site, as well as the dosage in the nodal region, affect the severity of the acute radiation-induced mucosal reaction. The severity of the early radiation-induced reaction is higher in men, more advanced patients (higher T and N+ in TNM classification), irradiated into a larger area, and those in whom two-dimensional planning and complementary chemoradiotherapy were applied. The late reaction of the skin and subcutaneous tissue was dominated by patients irradiated in the nodal regions and those with a higher intensity of early radiation-induced reaction. Conclusions: Supplementary radiotherapy or radiochemotherapy in salivary gland cancer is associated with acceptable toxicity which has no effect on overall survival.

scholarly journals Late complications of radiosurgery for cerebral arteriovenous malformations: report of 5 cases of chronic encapsulated intracerebral hematomas and review of the literature

2020 ◽  
Author(s):  
Stephanos Finitsis ◽  
René Anxionnat ◽  
Valerie Bernier ◽  
Isabelle Buccheit ◽  
Olivier Klein ◽  
...  
Keyword(s):  
Late Complication ◽  
Latency Period ◽  
Surgical Excision ◽  
Complete Removal ◽  
Late Complications ◽  
Intracerebral Hematoma ◽  
Cystic Component ◽  
Radiation Induced ◽  
Early Radiation ◽  
Induced Changes

Abstract Background: Chronic encapsulated intracerebral hematomas (CEIHs) are a rare, late complication of radiosurgery for intracranial AVM. We present 5 cases treated mostly by surgical excision and review the literature. Methods: Patients (age 39, 42, 36, 31, 62) presented with headache, paresthesia, hemiparesis or were asymptomatic. CEIHs presented 10 to 13 years (median 12 years) post radiosurgery. Three patients had demonstrated early radiation induced changes post radiosurgery. Angiographic cure, assessed with DSA, was present in all cases except 1 case with a small nidus remnant. MRI demonstrated mixed lesions with a solid enhancing part, organized hematoma and extensive surrounding edema while three cases had also a cystic component. Results: Excision of the CEIHs with complete or partial removal of the capsule was perfomed in 4 patients and resulted in marked clinical improvement. On patient was managed conservatively with administration of steroids as surgery was judged excessively hazardous with eventual stabilization of his symptoms. Conclusions: CEIHs are rare, late complications of radiosurgery for cranial AVM. They may be asymptomatic or provoke symptoms and may be preceded by early radiation induced changes. Complete removal of CEIHS is an effective treatment. Because of the long latency period of CEIHs, patients who had radiosurgery for brain AVMs should be followed by MRI at least 10 years even after complete obliteration. Keywords: Arteriovenous Malformation, Radiosurgery, Complication, Chronic encapsulated intracerebral hematoma

scholarly journals Surgery treatment for early radiation ulcer developed after endovascular intervention

2020 ◽  
Vol 29 (4) ◽  
pp. 158-163
Author(s):  
V.V. Pasov ◽  
◽  
V.A. Korotkov ◽  
Keyword(s):  
Left Shoulder ◽  
Radiation Injuries ◽  
En Bloc ◽  
Endovascular Interventions ◽  
Radiation Ulcer ◽  
Radiation Induced ◽  
Early Radiation ◽  
Angioplasty And Stenting ◽  
Shoulder Blade ◽  
Dose Tolerance

Delayed radiation damage to soft tissue and its treatment are described in detail. In the majority of cases the development of late radiation injuries were resulted from the radiation therapy of cancer. Early radiation injuries rarely occur. Most of early radiation-induced pathologic changes result from occupational radiation exposure or violation of radiation safety regulations. Nowadays we witness widespread clinical use of endovascular interventions, that can last for many hours. Concurrently, publications of research groups reported on complications in patients underwent endovascular procedures have appeared. The reported complications can be a result of increas-ing radiation dose to normal tissue over dose tolerance limits. The article presents a case of the successful treatment of early radiation ulcer on the left shoulder blade developed as a result of coronography followed by transluminal balloon angioplasty and stenting of the ramus interven-tricularis anterior (RIVA). Fibrotic tissue and radiation ulcer were excised en bloc with a cuff of healthy tissue followed by single-stage plasty with interpolated thoracodorsal musculocutaneous flap. Due to the given treatment we managed to restore the patient’s health status and improve his quality of life.

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