Does Quality of Life Among Modified Radical Mastectomy and Breast Conservation Surgery Patients Differ? A 5-Year Comparative Study

Objectives: To assess the quality of life (QoL) of patients receiving Breast conservation surgery as compared to the Modified Radical Mastectomy. Study Design: A case control study. Duration of Study: The study took place from August 2018 to September 30th 2019. Methodology: A prospective study using non probability sampling technique was conducted at Pakistan Institute of Medical Sciences. Quality of life was assessed using a QOL-CSV to evaluate the physical, psychological, social, spiritual well-being as well as distress and fear factors. Data was analyzed using SPSS software 20 and chi square test was applied. Results: Out of a total of 50 cases of BCS and 166 cases of modified radical mastectomy, mean age in breast conservation surgery group was 50.14± 4.8 and in the control group 54.7± 6.3. In case-group there were moderate score in physical, social, and psychological well-being as well as in fear factor and distress of diagnosis. No comparable difference was observed between case and control group with respect to physical, psychological, or spiritual wellbeing, distress score and fear factor. However significant difference was found in the quality of life regarding social concerns. Conclusion: Breast conservation surgery was associated with significant improvements in quality of life scores in terms of social and psychological well-being, with comparable physical and spiritual wellbeing in study population.

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Role of breast conservation surgery (BCS) and modified radical mastectomy (MRM) in early breast cancer - A comparative study

Medpusle International Journal of Surgery ◽

10.26611/1061125 ◽

2019 ◽

Vol 11 (2) ◽

pp. 112-116

Author(s):

Bhupendra Jayant Patil ◽

◽

Shital M Dikle ◽

Keyword(s):

Breast Cancer ◽

Comparative Study ◽

Early Breast Cancer ◽

Breast Conservation ◽

Radical Mastectomy ◽

Breast Conservation Surgery ◽

Modified Radical Mastectomy ◽

Conservation Surgery

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Is quality of life after mastectomy comparable to that after breast conservation surgery? A 5-year follow up study from Mumbai, India

Quality of Life Research ◽

10.1007/s11136-019-02351-1 ◽

2019 ◽

Vol 29 (3) ◽

pp. 683-692

Author(s):

K. V. Deepa ◽

A. Gadgil ◽

Jenny Löfgren ◽

S. Mehare ◽

Prashant Bhandarkar ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Breast Conservation ◽

Radical Mastectomy ◽

Breast Conservation Surgery ◽

Breast Cancer Surgery ◽

Significant Difference ◽

Domain Scores

Abstract Purpose Breast cancer is the commonest cancer in women worldwide. Surgery is a central part of the treatment. Modified radical mastectomy (MRM) is often replaced by breast conserving therapy (BCT) in high-income countries. MRM is still the standard choice, in low- and middle-income countries (LMICs) as radiotherapy, a mandatory component of BCT is not widely available. It is important to understand whether quality of life (QOL) after MRM is comparable to that after BCT. This has not been studied well in LMICs. We present, 5-year follow-up of QOL scores in breast cancer patients from India. Methods We interviewed women undergoing breast cancer surgery preoperatively, at 6 months after surgery, and at 1 year and 5 years, postoperatively. QOL scores were evaluated using FACT B questionnaire. Average QOL scores of women undergoing BCT were compared with those undergoing MRM. Total scores, domain scores and trends of scores over time were analyzed. Results We interviewed 54 women with a mean age of 53 years (SD 9 ± years). QOL scores in all the women, dipped during the treatment period, in all subscales but improved thereafter and even surpassed the baseline in physical, emotional and breast-specific domains (p < 0.05) at 5 years. At the end of 5 years, there was no statistically significant difference between the MRM and BCT groups in any of the total or domain scores. Conclusion QOL scores in Indian women did not differ significantly between MRM and BCT in the long term. Both options are acceptable in the study setting.

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Cardiac dose reduction using deep inspiratory breath hold (DIBH) in radiation treatment of left sided breast cancer patients with breast conservation surgery and modified radical mastectomy

Journal of Medical Imaging and Radiation Sciences ◽

10.1016/j.jmir.2020.12.004 ◽

2021 ◽

Vol 52 (1) ◽

pp. 57-67

Author(s):

Shagun Misra ◽

Ashutosh Mishra ◽

Punita Lal ◽

Resham Srivastava ◽

Mrinalani Verma ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Treatment ◽

Breast Conservation ◽

Radical Mastectomy ◽

Breast Conservation Surgery ◽

Breath Hold ◽

Breast Cancer Patients ◽

Modified Radical Mastectomy ◽

Cardiac Dose ◽

Conservation Surgery

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Breast Conservation Surgery versus Modified Radical Mastectomy in the Management of Non Metastatic Inflammatory Breast Cancer

QJM ◽

10.1093/qjmed/hcab097.059 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Mohamed Elsayed Elshinawi ◽

Ahmed Gamal Eldin Osman ◽

Karim Fahmy Abdelmoaty ◽

Waleed Abdelsalam Abdelatty Anber

Keyword(s):

Breast Cancer ◽

Inflammatory Breast Cancer ◽

Breast Conservation ◽

Radical Mastectomy ◽

Conservative Surgery ◽

Breast Conservation Surgery ◽

Partial Mastectomy ◽

Cochrane Central Register ◽

Modified Radical Mastectomy ◽

Conservation Surgery

Abstract Background Inflammatory breast cancer (IBC), the most lethal form of breast cancer, constitutes 1–2% of all breast cancers in the United States. Multimodality therapy is the standard in management of non metastatic inflammatory breast cancer patients including neoadjuvant chemotherapy and endocrine therapy and mastectomy followed by post mastectomy radiation. A modified radical mastectomy has been the standard surgical procedure of choice. The objective of this systematic review and metanalysis is to estimate the pooled benefits and adverse effects of performing modified radical mastectomy versus breast conservation surgery in the management of non metastatic IBC. Objective To evaluate, review and analyze the outcome of non metastatic IBC patients treated with mastectomy or breast conservation surgery as an integral part of the multimodality treatment of the disease. To highlight the evidence and quality of the included studies. To share in modifying the current guidelines. Methods An electronic search was conducted from the inception till Jan 2020 in the following bibliographic databases: Medline via PubMed, SCOPUS, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, and Google Scholar to identify relevant articles. We used different combinations of the following queries: ("Inflammatory Breast cancer" OR "breast cancer") AND ("Conservative Treatment" [Mesh] OR "conservative surgery" OR "breast conservative surgery" OR "partial mastectomy"). The search have been done with no limit regarding the year publication. Results After reviewing five studies we found that our results favors the use of modified radical mastectomy over breast conservation surgery in terms of the overall survival and breast cancer specific free survival, however, partial mastectomy could be an effective and safe option in selected group of patients with non metastatic IBC based on the response to NAC an patient’s preference. Conclusions Breast surgery is of great significance to the clinical outcomes of IBC. Standard mastectomy shouldn’t be the only recommended surgical treatment. Individualized surgical procedures can be safely performed in non-metastatic IBC patients based on the response of NAC and patient’s preference.

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