Cardiac dose reduction using deep inspiratory breath hold (DIBH) in radiation treatment of left sided breast cancer patients with breast conservation surgery and modified radical mastectomy

2021 ◽  
Vol 52 (1) ◽  
pp. 57-67
Author(s):  
Shagun Misra ◽  
Ashutosh Mishra ◽  
Punita Lal ◽  
Resham Srivastava ◽  
Mrinalani Verma ◽  
...  
QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Elsayed Elshinawi ◽  
Ahmed Gamal Eldin Osman ◽  
Karim Fahmy Abdelmoaty ◽  
Waleed Abdelsalam Abdelatty Anber

Abstract Background Inflammatory breast cancer (IBC), the most lethal form of breast cancer, constitutes 1–2% of all breast cancers in the United States. Multimodality therapy is the standard in management of non metastatic inflammatory breast cancer patients including neoadjuvant chemotherapy and endocrine therapy and mastectomy followed by post mastectomy radiation. A modified radical mastectomy has been the standard surgical procedure of choice. The objective of this systematic review and metanalysis is to estimate the pooled benefits and adverse effects of performing modified radical mastectomy versus breast conservation surgery in the management of non metastatic IBC. Objective To evaluate, review and analyze the outcome of non metastatic IBC patients treated with mastectomy or breast conservation surgery as an integral part of the multimodality treatment of the disease. To highlight the evidence and quality of the included studies. To share in modifying the current guidelines. Methods An electronic search was conducted from the inception till Jan 2020 in the following bibliographic databases: Medline via PubMed, SCOPUS, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, and Google Scholar to identify relevant articles. We used different combinations of the following queries: ("Inflammatory Breast cancer" OR "breast cancer") AND ("Conservative Treatment" [Mesh] OR "conservative surgery" OR "breast conservative surgery" OR "partial mastectomy"). The search have been done with no limit regarding the year publication. Results After reviewing five studies we found that our results favors the use of modified radical mastectomy over breast conservation surgery in terms of the overall survival and breast cancer specific free survival, however, partial mastectomy could be an effective and safe option in selected group of patients with non metastatic IBC based on the response to NAC an patient’s preference. Conclusions Breast surgery is of great significance to the clinical outcomes of IBC. Standard mastectomy shouldn’t be the only recommended surgical treatment. Individualized surgical procedures can be safely performed in non-metastatic IBC patients based on the response of NAC and patient’s preference.


2019 ◽  
Vol 6 (7) ◽  
pp. 2405
Author(s):  
N. R. Sajikumar ◽  
S. Syamsunder ◽  
Carol Pinheiro

Background: Breast cancer is a common cancer among women in India and its incidence is increasing in an alarming rate. There is a paradigm shift in the management of early breast cancer with more emphasis given to breast conservation treatments. This study aimed to assess the proportion of patient underwent breast conservation surgery and reasons to choose breast conservation surgery or modified radical mastectomy in early breast cancer.Methods: Information of 41 patients with early breast carcinoma who attended the institute during the study period and who can choose either modified radical mastectomy or breast conservation surgery depending on their wish are included in the study group and the data thus obtained was entered in MS Excel data sheet and analysed using SPSS 16 software.Results: It was observed that the proportion of women selecting breast conserving therapy increased with improved literacy status. Similarly, menstrual status and location of tumor do have an influence in choosing breast conserving surgery with significant statistical correlation. However, unlike the previous studies we did not find any statistically significant association between age and surgical decision. Similarly, place of residence, and employment status of the patient does not influence the decision to undergo breast conservation surgery.Conclusions: We have to create awareness in the society about the safety of breast conservation treatment to popularize this modality of treatment there by more and more organs can be preserved. 


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