A Prospective Study Comparing the Role of 18 FDG PET-CT with Contrast-Enhanced Computed Tomography and Tc99m Bone Scan for Staging Locally Advanced Breast Cancer

2021 ◽  
Author(s):  
Sandeep Bhoriwal ◽  
S. V. S. Deo ◽  
Rakesh Kumar ◽  
Sanjay Thulkar ◽  
Ajay Gogia ◽  
...  
Keyword(s):  
Bone Scan ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Contrast Enhanced ◽  
Pet Ct ◽  
Enhanced Computed Tomography ◽  
A Prospective Study ◽  
Fdg Pet Ct ◽  
Contrast Enhanced Computed Tomography

The role of 18F-FDG-PET/CT in predicting the histopathological response in locally advanced cervical carcinoma treated by chemo-radiotherapy followed by radical surgery: a prospective study

2019 ◽  
Vol 47 (5) ◽  
pp. 1228-1238
Author(s):  
Vittoria Rufini ◽  
Angela Collarino ◽  
Maria Lucia Calcagni ◽  
Guido Maria Meduri ◽  
Valentina Fuoco ◽  
...  
Keyword(s):  
Prospective Study ◽  
Radical Surgery ◽  
Locally Advanced ◽  
Histopathological Response ◽  
Advanced Cervical Carcinoma ◽  
Pet Ct ◽  
18F Fdg ◽  
A Prospective Study ◽  
Fdg Pet Ct

scholarly journals Prognostic Predicting Role of Contrast-Enhanced Computed Tomography for Locally Advanced Pancreatic Adenocarcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Chien-shan Cheng ◽  
Wei Liu ◽  
Liangping Zhou ◽  
Wei Tang ◽  
Ailing Zhong ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pancreatic Adenocarcinoma ◽  
Locally Advanced ◽  
Tumour Volume ◽  
Contrast Enhanced ◽  
Locally Advanced Pancreatic Adenocarcinoma ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography ◽  
Advanced Pancreatic Adenocarcinoma

Introduction. Contrast-enhanced computed tomography (CECT) imaging is commonly used to assess pancreatic adenocarcinoma (PAC). However, the value of semiquantitative and quantitative assessments of CECT parameters used to predict survival in PAC remains unknown. This study aims to investigate the prognostic role of pretreatment CECT imaging in patients with locally advanced pancreatic adenocarcinoma (LAPAC). Materials and Methods. From June 2013 to May 2017, eighty-six newly diagnosed patients with pathologically and radiologically confirmed LAPAC were retrospectively recruited. All patients were evaluated by CECT and experienced gemcitabine-based chemotherapy. The relationship between overall survival (OS) and clinical factors including age, sex, serum carbohydrate antigen 19-9 value, and CECT findings (including tumour location, tumour volume, peripancreatic involvement, blood vessel involvement, tumour enhanced rate, and distance liver metastasis) was determined using Cox proportional hazard regression models, and a nomogram was constructed for the prediction of 1- and 1.5-year survival rates of patients with LAPAC. Results. On univariate analysis, patients who had a tumour enhanced rate (TER) less than 80.465% and those who had a TER ≥ 80.465% are with a 3.587-fold increase in OS (p<0.001). After multivariate Cox regression, a nomogram was established based on a new model containing the predictive variables of high Ca19-9 level, higher clinical stages, larger tumour volume, the presence of peripancreatic involvement, and liver metastases. The model displayed good accuracy in predicting OS with a C-index of 0.614. The calibration plots also showed a good discrimination and calibration of the nomogram between the predicted and observed survival probabilities. Conclusion. Our results showed that TER can be used to predict survival in LAPAC, and we developed a nomogram for determining the prognosis of patients with LAPAC. However, the purposed nomogram still requires external data verification in future applications.

Role of 18F-FDG PET/CT in identifying distant metastatic disease missed by conventional imaging in patients with locally advanced breast cancer

2013 ◽  
Vol 34 (6) ◽  
pp. 557-561 ◽  
Author(s):  
Kuruva Manohar ◽  
Bhagwant R. Mittal ◽  
Amit Bhoil ◽  
Anish Bhattacharya ◽  
Gurpreet Singh
Keyword(s):  
Breast Cancer ◽  
Fdg Pet ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Conventional Imaging ◽  
Distant Metastatic Disease ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

The factors affecting pathologic complete response after neoadjuvant chemotherapy and the role of 18-FDG-PET/CT in patients with locally advanced breast cancer.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e12539-e12539
Author(s):  
Faysal Dane ◽  
Serap Kaya ◽  
Hatice Odabas ◽  
Aydin Aytekin ◽  
Nilgun Yildirim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Locally Advanced Breast Cancer ◽  
Locally Advanced ◽  
Pathologic Complete Response ◽  
Complete Response ◽  
Factors Affecting ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals A quantitative comparison of gross tumor volumes delineated on [18F]-FDG-PET/CT scan and contrast-enhanced computed tomography scan in locally advanced head and neck carcinoma treated with Intensity Modulated Radiotherapy

2017 ◽  
Vol 3 (3) ◽  
Author(s):  
Nagarjuna Burela ◽  
Tej Prakash Soni ◽  
Nidhi Patni ◽  
JK Bhagat ◽  
T Senthil Kumar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Fdg Pet ◽  
Locally Advanced ◽  
Intensity Modulated Radiotherapy ◽  
Positron Emission ◽  
Contrast Enhanced ◽  
Pet Ct ◽  
One Year ◽  
Enhanced Computed Tomography ◽  
Fdg Pet Ct

<p>Accurate tumor diagnosis is important in highly conformal techniques such as Intensity Modulated Radiotherapy (IMRT), which aims for high therapeutic ratio. We compared Gross Tumor Volume (GTV) (primary and nodal) delineated on <sup>18</sup>F-fluorodeoxyglucose positron emission tomography ([<sup>18</sup>F]-FDG-PET) scan to those delineated on contrast-enhanced computed tomography (CECT) scan and its impact on staging treated by IMRT.<strong> </strong>A total of 30 consecutive patients with locally advanced squamous cell carcinoma of head and neck were included in this study. FDG-PET and CECT scans were performed with dedicated positron emission tomography–computed tomography (PET/CT) scanner in a single session as part of radiotherapy treatment planning for IMRT. After treatment with concurrent chemoradiotherapy, all patients were followed for one year. Three out of 30 patients were excluded from the final analysis, as there was complete remission in PET/CT after neoadjuvant chemotherapy. For remaining 27 cases, the primary sites were 17 oropharynx, 2 hypopharynx, 7 larynx and 1 unknown primary with secondary neck node. PET–CT resulted in changes of CT-based staging in 25% patients (up-staged in 3 and down-staged in 4). GTV delineated on PET vs CT scan was GTV-PET (primary) of 20.15 cm<sup>3</sup> vs GTV-CT (primary) of 18.75 cm<sup>3</sup>, <em>p</em> = 0.803; and GTV-PET (nodes) of 28.45 cm<sup>3</sup> vs GTV-CT (nodes) of 21.56 cm<sup>3</sup>, <em>p</em> = 0.589. The mismatch between two target volumes was statistically insignificant (<em>p</em> = 0.635 for GTV primary, <em>p</em> = 0.187 for nodes). The mean GTV-PET outside CT for primary was 5.83 cm<sup>3</sup>, and for node was 8.47 cm<sup>3</sup>. Median follow-up was 12 months. One-year loco-regional control was 92%. The target delineation of GTV can be improved with functional imaging [<sup>18</sup>F]-FDG-PET/CT.</p>

A retrospective study comparing contrast-enhanced computed tomography with 18F-FDG-PET/CT in the early follow-up of patients with retroperitoneal sarcomas

2013 ◽  
Vol 34 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Artor Niccoli-Asabella ◽  
Corinna Altini ◽  
Antonio Notaristefano ◽  
Nunzio Merenda ◽  
Maria L. Altieri ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Contrast Enhanced ◽  
Pet Ct ◽  
18F Fdg ◽  
Retroperitoneal Sarcomas ◽  
Enhanced Computed Tomography ◽  
Fdg Pet Ct ◽  
Contrast Enhanced Computed Tomography
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