Recycling printed circuit boards (PCBs) is an important solution not only to treat hazardous waste but also to recover valuable materials. This research focus on optimizing the leaching copper process from waste PCBs to recycle. This process was performed in Fe2(SO4)3 solution at room temperature and using H2O2 as an oxidant. For optimization, response surface methodology was used to investigate the different parameters, including Fe2(SO4)3 concentration, volume of H2O2 addition and leaching time. Design Expert 10.0 software was applied to design the experiments and calculate the regression equation of the response function. As a result, a model was established which is compatible with the experimental data at the correlation coefficient (R2) of 0.99. The optimal conditions were identified as Fe2(SO4)3 concentration of 0.35 M, volume of H2O2 addition at 10 mL and leaching time of 10 h. Under this condition, leaching efficiency of 90.5 percent was achieved. After leaching, copper was recovered from extract solution by electrochemical technology with the efficiency of 85 percent. The results from this study hence proposed a very promising method for recycling copper in PCBs.