Altered Antioxidant Defenses in Drug-Naive First Episode Patients with Schizophrenia Are Associated with Poor Treatment Response to Risperidone: 12-Week Results from a Prospective Longitudinal Study

2021 ◽  
Author(s):  
Xi Rong Li ◽  
Mei Hong Xiu ◽  
Xiao Ni Guan ◽  
Yue Chan Wang ◽  
Jun Wang ◽  
...  

2012 ◽  
Vol 32 (6) ◽  
pp. 579-586 ◽  
Author(s):  
Dimitri Ceroni ◽  
Xavier Martin ◽  
Cécile Delhumeau-Cartier ◽  
René Rizzoli ◽  
André Kaelin ◽  
...  


2011 ◽  
Vol 70 (7) ◽  
pp. 672-679 ◽  
Author(s):  
Nancy C. Andreasen ◽  
Peg Nopoulos ◽  
Vincent Magnotta ◽  
Ronald Pierson ◽  
Steven Ziebell ◽  
...  


2015 ◽  
Vol 41 (5) ◽  
pp. 1162-1170 ◽  
Author(s):  
Valeria Mondelli ◽  
Simone Ciufolini ◽  
Martino Belvederi Murri ◽  
Stefania Bonaccorso ◽  
Marta Di Forti ◽  
...  


2004 ◽  
Vol 34 (2) ◽  
pp. 277-284 ◽  
Author(s):  
J. ADDINGTON ◽  
S. VAN MASTRIGT ◽  
D. ADDINGTON

Background. The duration of untreated psychosis has been postulated to be a predictor of clinical outcome in schizophrenia. Although several prospective studies support the relationship, some studies do not. These differences may be due to a number of methodological issues. The objectives of this study are: (i) to address many of the methodological limitations of earlier studies such as variations in sample size and selection, type of treatment provided, differences in measurement of DUP and outcome, and length of follow-up; and (ii) to examine the relationship between DUP and outcome in a prospective longitudinal study.Method. The DUP of 200 consecutive admissions to a first-episode programme was determined. The sample was followed over 2 years and pre-morbid functioning, symptoms, social and cognitive functioning and substance use were assessed longitudinally.Results. Two years after admission to the programme, longer DUP was significantly associated with high levels of positive symptoms and poor social functioning. Independently of other variables, DUP predicted positive symptoms and social functioning at 1 and 2 years.Conclusions. There is evidence that long DUP continues to have an influence on outcome up to 2 years. These results support ongoing efforts for early detection and intervention.



2013 ◽  
Vol 70 (10) ◽  
pp. 1031 ◽  
Author(s):  
Lena Palaniyappan ◽  
Tiago Reis Marques ◽  
Heather Taylor ◽  
Rowena Handley ◽  
Valeria Mondelli ◽  
...  


2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Sara Barbeito ◽  
Patricia Vega ◽  
Sonia Ruiz de Azúa ◽  
Margarita Saenz ◽  
Mónica Martinez-Cengotitabengoa ◽  
...  


2013 ◽  
Vol 150 (2-3) ◽  
pp. 538-541 ◽  
Author(s):  
Edwin H.M. Lee ◽  
Christy L.M. Hui ◽  
W.C. Chang ◽  
Sherry K.W. Chan ◽  
Y.K. Li ◽  
...  


2010 ◽  
Vol 117 (2-3) ◽  
pp. 292-293
Author(s):  
Eric Yu-Hai Chen ◽  
Christy Lai-Ming Hui ◽  
Eva Lai-Wah Dunn ◽  
May Yin-King Miao ◽  
Wai-Song Yeung ◽  
...  


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