Self-assembling peptide scaffolds as innovative platforms for drug and cell delivery systems in cardiac regeneration

2013 ◽  
Vol 3 (4) ◽  
pp. 330-335 ◽  
Author(s):  
Veronica A. C. Puig-Sanvicens ◽  
Carlos E. Semino
Keyword(s):  
Cardiac Regeneration ◽  
Delivery Systems ◽  
Cell Delivery ◽  
Self Assembling ◽  
Peptide Scaffolds

Designer Self-Assembling Peptide Scaffolds for Tissue Engineering and Regenerative Medicine

2014 ◽  
pp. 329-340
Author(s):  
Akihiro Horii ◽  
Xiumei Wang ◽  
Shuguang Zhang
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Self Assembling ◽  
Peptide Scaffolds

Barium alginate cell-delivery systems: correlation between technological parameters

2002 ◽  
Vol 242 (1-2) ◽  
pp. 389-391 ◽  
Author(s):  
M.L Torre ◽  
M Faustini ◽  
R Norberti ◽  
L Maggi ◽  
G Maffeo ◽  
...  
Keyword(s):  
Delivery Systems ◽  
Cell Delivery ◽  
Technological Parameters

ISDN2014_0395: REMOVED: Self‐assembling MMP‐2 cleavable hydrogel drug delivery systems for neural tissue injury

2015 ◽  
Vol 47 (Part_A) ◽  
pp. 116-117
Author(s):  
K. Koss ◽  
M. Churchward ◽  
K. Todd ◽  
L.D. Unsworth
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Tissue Injury ◽  
Neural Tissue ◽  
Delivery Systems ◽  
Self Assembling

Soy protein and chitin sponge-like scaffolds: from natural by-products to cell delivery systems for biomedical applications

2020 ◽  
Vol 22 (11) ◽  
pp. 3445-3460 ◽  
Author(s):  
Kevin Las Heras ◽  
Edorta Santos-Vizcaino ◽  
Tania Garrido ◽  
Francisco Borja Gutierrez ◽  
Jose Javier Aguirre ◽  
...  
Keyword(s):  
Soy Protein ◽  
Renewable Resources ◽  
Biomedical Applications ◽  
Delivery Systems ◽  
Cell Delivery ◽  
Plant Proteins ◽  
By Products

Natural and renewable resources, such as plant proteins and marine polysaccharides, to manufacture scaffolds with suitable properties for biomedical applications.

scholarly journals Synergistic Fabrication of Dose–Response Chitosan/Dextran/β-Glycerophosphate Injectable Hydrogel as Cell Delivery Carrier for Cardiac Healing After Acute Myocardial Infarction

Dose-Response ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. 155932582094132
Author(s):  
Chongjun Hua ◽  
Jing Liu ◽  
Xiuhong Hua ◽  
Xinyu Wang
Keyword(s):  
Human Mesenchymal Stem Cells ◽  
Cardiac Regeneration ◽  
Myocardial Infarctions ◽  
Cell Delivery ◽  
Injectable Hydrogels ◽  
Remarkable Improvement ◽  
New Methods ◽  
Factors Analysis ◽  
Synergistic Approach

The human mesenchymal stem cells (hMSCs) therapy offering an encouraging the new methods to establish the conveying on the chitosan (C)/dextran (D)/β-glycerophosphate (β-GP) loaded with hMSCs to enhance the acute myocardial infarctions. The synthesized hMSCs-CD@β-GP system displayed the ratio of determination modules, size of the pore, absorbency, and the swellings ratio in the assortment of the 65 ka, 149 ± 39.8 µm, 92.2%, 42 ± 1.38, and 29 ± 1.9, respectively. The fabricated hMSCs-CD@β-GP was highly stable and physicochemical investigated and confirmed the suitability of the materials for cardiac regeneration applications. The in vitro examinations of the injectable hydrogels with hMSCs-CD@β-GP have recognized that the improved survival rate of the cells, increased the pro-inflammatory expressions factors, pro-angiogenic factors analysis confirmed the promising results of the ejection of fractions, fibrosis area, vessel density with decreased infractions size, with suggesting that the remarkable improvement of the heart regenerative function after myocardial infarctions. The new synergistic approach of the injectable hydrogels with hMSCs could able appropriate for the effective treatment of cardiac therapies after acute myocardial infarctions.

scholarly journals A self-assembling amphiphilic peptide nanoparticle for the efficient entrapment of DNA cargoes up to 100 nucleotides in length

Soft Matter ◽  
2020 ◽  
Vol 16 (6) ◽  
pp. 1678-1691 ◽  
Author(s):  
Shabnam Tarvirdipour ◽  
Cora-Ann Schoenenberger ◽  
Yaakov Benenson ◽  
Cornelia G. Palivan
Keyword(s):  
Dna Delivery ◽  
Delivery Systems ◽  
Viral Dna ◽  
Self Assembling ◽  
Double Stranded Dna ◽  
Amphiphilic Peptide ◽  
Low Efficiency

To overcome the low efficiency and cytotoxicity associated with most non-viral DNA delivery systems we developed a purely peptidic self-assembling system that is able to entrap single- and double-stranded DNA of up to 100 nucleotides in length.

scholarly journals Self-assembling peptide scaffolds for regenerative medicine

2012 ◽  
Vol 48 (1) ◽  
pp. 26-33 ◽  
Author(s):  
John B. Matson ◽  
Samuel I. Stupp
Keyword(s):  
Regenerative Medicine ◽  
Self Assembling ◽  
Peptide Scaffolds

scholarly journals Thermosensitive Self-Assembling Block Copolymers as Drug Delivery Systems

Polymers ◽  
2011 ◽  
Vol 3 (2) ◽  
pp. 779-811 ◽  
Author(s):  
Giulia Bonacucina ◽  
Marco Cespi ◽  
Giovanna Mencarelli ◽  
Gianfabio Giorgioni ◽  
Giovanni Filippo Palmieri
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Self Assembling
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