Establishment and characterization of NCC-UPS3-C1: a novel patient-derived cell line of undifferentiated pleomorphic sarcoma

Human Cell ◽  
2021 ◽  
Author(s):  
Ryuto Tsuchiya ◽  
Yuki Yoshimatsu ◽  
Rei Noguchi ◽  
Yooksil Sin ◽  
Takuya Ono ◽  
...  
2020 ◽  
Author(s):  
Carmelia M. Barreto ◽  
Luisa M. Solis-Soto ◽  
Ruth Salazar ◽  
Swati Gite ◽  
Edwin R. Parra ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Christopher S. Hong ◽  
Edwin Partovi ◽  
James Clune ◽  
Anita Huttner ◽  
Henry S. Park ◽  
...  

Intracranial undifferentiated pleomorphic sarcoma remains a rare pathology within the sarcoma literature that may arise primarily or secondary after radiation therapy. Despite first-line treatment with maximal surgical resection, followed by nonstandardized adjuvant chemotherapy/radiation regimens, clinical prognosis remains exceedingly poor. Furthermore, there is a lack of genetic or molecular characterization to guide potential for targeted therapies. We present genomic analysis of a radiation-induced intracranial undifferentiated pleomorphic sarcoma in an 83-year-old woman with notable KIT and PDGFRA alterations. Further similar genomic studies of intracranial pleomorphic sarcoma are needed to develop better therapies for this rare but challenging disease entity.


2017 ◽  
Vol 4 (2) ◽  
pp. 102-104
Author(s):  
Sunil Vitthalrao Jagtap ◽  
◽  
Cyrus Dara Jokhi ◽  
Swati S Jagtap ◽  
Ritvij Patankar ◽  
...  

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