scholarly journals Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion in the elderly: case report and literature review

2020 ◽  
Vol 9 (4) ◽  
pp. 182-186 ◽  
Author(s):  
Toshihiko Masago ◽  
Susumu Kobayakawa ◽  
Yuu Ohtani ◽  
Kenjirou Taniguchi ◽  
Takuji Naka ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
The Elderly ◽  
Xp11.2 Translocation

scholarly journals Xp11.2 translocation renal cell carcinoma with TFE3 gene fusion: A case report

2017 ◽  
Author(s):  
Xiang Pan ◽  
Jing Quan ◽  
Liwen Zhao ◽  
Wenhua Li ◽  
Benlin Wei ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Xp11.2 Translocation

scholarly journals Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: A Case Report with Immunohistochemical and Cytological Features

2016 ◽  
Vol 06 (01) ◽  
pp. 19-25
Author(s):  
Takuji Tanaka ◽  
Kuniaki Hirai ◽  
Fumimasa Etori ◽  
Masashi Matsuyama ◽  
Naoki Watanabe ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Cytological Features ◽  
Xp11.2 Translocation

scholarly journals A Rare Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: Case Report of 8 Cases and Review of the Literature

2021 ◽  
Vol 5 (1) ◽  
pp. 30
Author(s):  
Mohammad Arman Hossain ◽  
Jannatul Maoya Bashanti ◽  
Xiaoyong Dong ◽  
Shun Gao ◽  
Hang Tong ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Review Of The Literature ◽  
Xp11.2 Translocation

Renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion: imaging findings in 21 patients

2016 ◽  
Vol 27 (2) ◽  
pp. 543-552 ◽  
Author(s):  
Xiao Chen ◽  
Qingqiang Zhu ◽  
Baoxin Li ◽  
Wenjing Cui ◽  
Hao Zhou ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Fusion Imaging ◽  
Imaging Findings ◽  
Xp11.2 Translocation

scholarly journals Clear cell renal cell carcinoma with vaginal and brain metastases: a case report and literature review

2009 ◽  
Vol 1 (2) ◽  
pp. 16
Author(s):  
Tobe Samuel Momah ◽  
Dhanan Etwaru ◽  
Phillip Xiao ◽  
Vasantha Kondamudi
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Cell Renal Cell Carcinoma

MDCT Findings of Renal Cell Carcinoma Associated With Xp11.2 Translocation and TFE3 Gene Fusion and Papillary Renal Cell Carcinoma

2015 ◽  
Vol 204 (3) ◽  
pp. 542-549 ◽  
Author(s):  
Sungmin Woo ◽  
Sang Youn Kim ◽  
Myoung Seok Lee ◽  
Kyung Chul Moon ◽  
See Hyung Kim ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Gene Fusion ◽  
Papillary Renal Cell Carcinoma ◽  
Xp11.2 Translocation

scholarly journals Temsirolimus in the treatment of renal cell carcinoma associated with Xp11.2 translocation/TFE gene fusion proteins: a case report and review of literature

Rare Tumors ◽  
2009 ◽  
Vol 1 (2) ◽  
pp. 164-166
Author(s):  
Jigarkumar Parikh ◽  
Teresa Coleman ◽  
Nidia Messias ◽  
James Brown
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Signaling Pathways ◽  
Renal Cell ◽  
Gene Fusion ◽  
Mammalian Target Of Rapamycin ◽  
World Health ◽  
Target Of Rapamycin ◽  
Tyrosine Kinase Receptor ◽  
Xp11.2 Translocation

Xp11.2 translocation renal cell carcinomas (TRCCs) are a rare family of tumors newly recognized by the World Health Organization (WHO) in 2004. These tumors result in the fusion of partner genes to the TFE3 gene located on Xp11.2. They are most common in the pediatric population, but have been recently implicated in adult renal cell carcinoma (RCC) presenting at an early age. TFE3-mediated direct transcriptional upregulation of the Met tyrosine kinase receptor triggers dramatic activation of downstream signaling pathways including the protein kinase B (Akt)/phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) pathways. Temsirolimus is an inhibitor of mammalian target of rapamycin (mTOR) kinase, a component of intracellular signaling pathways involved in the growth and proliferation of malignant cells. Here we present a case of a 22-year old female who has been treated with temsirolimus for her Xp11.2/ TFE3 gene fusion RCC.

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