A case of proliferative glomerulonephritis with monoclonal IgG3κ deposits accompanied by glomerular capillary microaneurysms

2022 ◽  
Author(s):  
Akiko Mii ◽  
Mika Terasaki ◽  
Shinobu Kunugi ◽  
Miyako Seki ◽  
Tetsuya Kashiwagi ◽  
...  
Keyword(s):  
Proliferative Glomerulonephritis ◽  
Glomerular Capillary

scholarly journals A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Homare Shimohata ◽  
Kentaro Ohgi ◽  
Hiroshi Maruyama ◽  
Yasunori Miyamoto ◽  
Mamiko Takayashu ◽  
...  
Keyword(s):  
Light Microscopy ◽  
Proliferative Glomerulonephritis ◽  
Light Chains ◽  
The Novel ◽  
Immunofluorescence Study ◽  
Pathological Findings ◽  
Mesangial Proliferation ◽  
Glomerular Capillary ◽  
Almost All ◽  
Capillary Walls

In 2004, the novel category of monoclonal IgG deposition disease has been proposed and termed “proliferative glomerulonephritis with monoclonal IgG deposits” (PGNMID). This disease is characterized by membranoproliferative glomerulonephritis and staining for a single light-chain isotype and gamma heavy-chain subclass. A 76-year-old male who had monoclonal gammopathy was referred to our hospital because of proteinuria. The renal biopsy showed diffuse thickening of the glomerular capillary walls with focal mesangial proliferation. On immunofluorescence study, only IgG1 among the four subclasses and lambda light chains were detected mainly in the glomerular capillary walls. From these results, we diagnosed our case as PGNMID showing predominantly membranous features. Almost all pathological findings on light microscopy of PGNMID are membranoproliferative GN or endocapillary proliferative GN, while membranous GN cases are rare. Here, we present the case of PGNMID that showed predominantly membranous features on light microscopy.

Recovery of Damaged Glomerular Capillary Network with Endothelial Cell Apoptosis in Experimental Proliferative Glomerulonephritis

Nephron ◽  
1998 ◽  
Vol 79 (2) ◽  
pp. 206-214 ◽  
Author(s):  
Akira Shimizu ◽  
Yukinari Masuda ◽  
Hiroshi Kitamura ◽  
Masamichi Ishizaki ◽  
Yuichi Sugisaki ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Apoptosis ◽  
Capillary Network ◽  
Proliferative Glomerulonephritis ◽  
Endothelial Cell Apoptosis ◽  
Glomerular Capillary

scholarly journals Glomerular Damage in Experimental Proliferative Glomerulonephritis Under Glomerular Capillary Hypertension

2015 ◽  
Vol 40 (2) ◽  
pp. 188-199 ◽  
Author(s):  
Pei-Rong Wang ◽  
Hiroshi Kitamura ◽  
Akira Shimizu ◽  
Nobuaki Yamanaka
Keyword(s):  
Proliferative Glomerulonephritis ◽  
Glomerular Capillary ◽  
Glomerular Capillary Hypertension ◽  
Glomerular Damage

An immunohistological study of epidermal growth factor receptor and neu receptor expression in proliferative glomerulonephritis

Pathology ◽  
1993 ◽  
Vol 25 (4) ◽  
pp. 327-332 ◽  
Author(s):  
Prabir Roy-Chaudhury ◽  
Michael C. Jones ◽  
John G. Simpson ◽  
Alison M. Macleod ◽  
Neva E. Haites ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Receptor Expression ◽  
Proliferative Glomerulonephritis ◽  
Epidermal Growth ◽  
Immunohistological Study
Sign in / Sign up

Export Citation Format

Share Document