Simultaneous spectrophotometric determination of thiamine and pyridoxine in multivitamin dosage forms using H-point standard addition and Vierodt᾿s methods

2018 ◽  
Vol 15 (7) ◽  
pp. 1603-1612 ◽  
Author(s):  
O. H. Rebwar ◽  
Y. M. Hunar ◽  
S. J. Hijran
Keyword(s):  
Spectrophotometric Determination ◽  
Standard Addition ◽  
Dosage Forms

Collaborative Study of the Spectrophotometric Determination of Procainamide Hydrochloride

1976 ◽  
Vol 59 (4) ◽  
pp. 807-810
Author(s):  
Jeffrey C Hamm
Keyword(s):  
Sodium Hydroxide ◽  
Acid Medium ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Collaborative Study ◽  
Dosage Forms ◽  
Standard Deviations

Abstract The USP analysis for procainamide HCl is titrimetric and relatively nonspecific, capsule and tablet dyes may interfere, and the method is not applicable to coated tablets. In the spectrophotofluorometric method the sample deteriorates when exposed to a xenon source. In the ultraviolet spectrophotometric method reported here, the sample is dispersed in acid medium, possible interferences are extracted in chloroform, base is added, procainamide is extracted in chloroform, the residue is dissolved in sodium hydroxide, and the compound is measured by absorption at 272 nm and comparison with a standard. Recoveries of standards added to capsule, tablet, and injection composites ranged from 99.3 to 102%. Twelve collaborators reported duplicate assay results for all 3 dosage forms with per cent standard deviations for 5 samples ranging from 1.01 to 1.27%. The method has been adopted as official first action.

Utilization of N-bromosuccinimide for the sensitive spectrophotometric determination of pipazethate HCl as antitussive drug in pure and dosage forms

2021 ◽  
Author(s):  
Mohammed A.S. Abourehab ◽  
Mostafa H.K. Shahin ◽  
Ragaa El Sheikh ◽  
Abd Ellateif ◽  
Shymaa M. Fawzi ◽  
...  
Keyword(s):  
Spectrophotometric Determination ◽  
Dosage Forms

Spectrophotometric Determination of Piroxicam via Chelation with Fe(III) in Commercial Dosage Forms

2009 ◽  
Vol 56 (6) ◽  
pp. 1083-1091 ◽  
Author(s):  
Syed Najmul Hejaz Azmi ◽  
Bashir Iqbal ◽  
Muna Ahmed Mohad Jaboob ◽  
Warda Ali Said Al Shahari ◽  
Nafisur Rahman
Keyword(s):  
Spectrophotometric Determination ◽  
Dosage Forms

Fluorometric and Spectrophotometric Determination of Pirbuterol Hydrochloride in Authentic and Dosage Forms

1985 ◽  
Vol 68 (6) ◽  
pp. 1222-1225
Author(s):  
Mohamed E Mohamed ◽  
Hassan Y Aboul-Enein
Keyword(s):  
Potentiometric Titration ◽  
Alkaline Medium ◽  
Spectrophotometric Determination ◽  
Fluorescence Intensity ◽  
Perchloric Acid ◽  
Authentic Sample ◽  
Dosage Forms ◽  
Fluorometric Method ◽  
The Mean

Abstract Pirbuterol hydrochloride has been assayed in alkaline medium by using a fluorometric method to measure fluorescence intensity at 372 nm with excitation at 310 nm and by the ▵A method at 242 nm.The linearity ranges are 0.5-4 μg/mL and 10-50 μg/mL, respectively. An authentic pirbuterol HC1 sample was analyzed by nonaqueous potentiometric titration using 0.1N perchloric acid, and the results were compared with those for fluorometric and AA methods. The mean percent recoveries for the authentic sample were 98.72 ± 1.13 and 99.24 ± 0.85, respectively. When applied to commercial capsules containing 10 mg and 15 mg each, the fluorometric method gave mean percent recoveries of 101.11 ± 1.05 and 98.12 ± 0.93; the ▵A method gave mean percent recoveries of 100.57 ± 0.83 and 97.80 ± 0.75, respectively.

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