scholarly journals Statistical Signal Detection as a Routine Pharmacovigilance Practice: Effects of Periodicity and Resignalling Criteria on Quality and Workload

Drug Safety ◽  
2015 ◽  
Vol 38 (12) ◽  
pp. 1219-1231 ◽  
Author(s):  
Magnus Lerch ◽  
Peter Nowicki ◽  
Katrin Manlik ◽  
Gabriela Wirsching
1973 ◽  
pp. 19-35 ◽  
Author(s):  
DANIEL P. MEYER ◽  
HERBERT A. MAYER

1980 ◽  
Vol 50 (2) ◽  
pp. 511-517
Author(s):  
David Braff ◽  
Dennis Saccuzzo ◽  
Rick Ingram ◽  
Brian Mc Neill ◽  
Richard Langford

Five experiments studied practice effects for 4, 7, 11 subjects on visual backward masking using a signal-detection procedure under various conditions. Exp. I determined the minimum perceptible critical stimulus duration (CSD) for criterion identification of a target stimulus, the letter T or A. In Exp. II, the stimulus was presented at the critical stimulus duration (CSD) followed by a pattern mask at intervals of 20 to 120 msec. for 15 separate sessions. In Exp. III ( N = 4) the mask followed the CSD in intervals of 2-msec. increments until subjects reached criterion accuracy. Exps. IV and V ( Ns = 4, 7) provided partial replications of Exps. II and III. Naive subjects were used, and the stimulus duration was constant for all subjects. When masking functions were obtained at a threshold, considerable variability was found and subjects improve slowly or not at all over sessions. With a fixed suprathreshold stimulus, all subjects improve with practice. The importance of these findings is discussed as they relate to common (and largely untested) assumptions made in the backward masking and perception literature.


Author(s):  
David E. Clement

Sixteen male subjects were run in groups of four on 720 trials of a 16-alternative, forced-choice, visual signal-detection task. The first and third blocks of 240 trials required individual judgments concerning target location. The second block of 240 trials required a group decision as to target location for two groups of subjects, and individual responses followed by a group decision for the other two groups. Comparisons were made among individual performance, real group performance, and the performance of two types of pseudogroup (derived from individual data) using an information-integration and a decision-threshold model. Group performance was better than individual performance, and was midway between the performances predicted by the two pseudogroup models, indicating that neither of the latter were adequate models for group performance. Real groups showed some characteristics both of independence and dependence among subjects, with some apparent use of logical decision rules in pooling individual information. Groups which made both individual and group responses on the second block of trials showed greater increases in sensitivity with practice than groups which made only group responses. It appeared that making individual responses had specific practice effects on subsequent individual performance, and these effects were greater in magnitude than the practice effects resulting from making group responses.


Drug Safety ◽  
2020 ◽  
Vol 43 (10) ◽  
pp. 999-1009 ◽  
Author(s):  
Lovisa Sandberg ◽  
Henric Taavola ◽  
Yasunori Aoki ◽  
Rebecca Chandler ◽  
G. Niklas Norén

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