Substantial cost savings by better glycaemic control in T1DM

Recent years have seen the approvals, more so in the EU than the United States, of follow-on biological drugs. These products have been new formulations of recombinant therapeutic proteins, developed to compete with the marketed originator products. Intended to closely mimic the originator products in terms of chemistry and therapeutic properties, these so-called ‘biosimilar’ products were initially conceived to be developed according to abbreviated development programmes, presumably at a substantial cost savings to both the drug developer and the consumer. With several such products now recently approved, however, it has become clear that their development programmes have been quite extensive and not particularly abbreviated. Accordingly, cost savings to consumers appear to be relatively modest.

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The factors behind working in virtual community

Journal of Global Operations and Strategic Sourcing ◽

10.1108/jgoss-03-2018-0011 ◽

2019 ◽

Vol 12 (2) ◽

pp. 246-267 ◽

Cited By ~ 1

Author(s):

Anitha Acharya

Keyword(s):

Virtual Teams ◽

Virtual Community ◽

Cost Savings ◽

Working Hours ◽

Substantial Cost ◽

Content Type ◽

Part Time ◽

Research Findings ◽

Hourly Basis ◽

Practical Implications

Purpose In this paper, the prior research on virtual teams was reviewed to assess the state of the literature. The purpose of this paper is to determine why individuals prefer working in virtual teams (also termed liquid workers and part-time workers). Previous researchers have focussed on the benefits that organizations receive if they hire liquid workers, but to date, no research has been conducted to determine the perspective of these liquid workers. The various definitions of virtual teams are discussed and an integrative definition is proposed that suggests all teams may be defined in terms of their extent of virtualness. Design/methodology approach A systematic review of the literature on virtual teams was conducted. The data were collected from 12 informants. A thematic analysis was used to analyse the data. Findings Six main themes were identified, namely, pliability, opportunities, increased earnings, vigour, family and transportation. Research limitations/implications This study was conducted in a three-metropolitan city in India and warrants being extended to rural and international settings to gain additional insights and confirmation of the research findings. Practical implications It is suggested that organizations who recruit liquid workers will be in a position for substantial cost savings; this is because organizations usually make payment of liquid workers’ wages on an hourly basis. This will help the organizations to schedule the number of working hours depending on their needs. Originality/value The current study is novel as there is a paucity of research in identifying the factors behind working in the virtual community in India. This study presents the first research of its kind to the best knowledge of the author, and the findings will be valuable for companies who are looking for cost savings.

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Documenting the Benefits and Cost Savings of a Large Multistate Cancer Pathway Program From a Payer's Perspective

Journal of Oncology Practice ◽

10.1200/jop.2012.000871 ◽

2013 ◽

Vol 9 (5) ◽

pp. e241-e247 ◽

Cited By ~ 30

Author(s):

Eugene D. Kreys ◽

Jim M. Koeller

Keyword(s):

Clinical Pathways ◽

Cost Savings ◽

Substantial Cost ◽

Physician Compliance

Broadly implemented clinical pathways can achieve reasonable physician compliance, resulting in substantial cost savings.

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Appropriateness of using granulocyte colony-stimulating factor (G-CSF) for primary prophylaxis of febrile neutropenia in solid tumors

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155219875507 ◽

2019 ◽

Vol 26 (2) ◽

pp. 428-433

Author(s):

Elahe Laali ◽

Jinous Fazli ◽

Sanambar Sadighi ◽

Mehdi Mohammadi ◽

Kheirollah Gholami ◽

...

Keyword(s):

Febrile Neutropenia ◽

Solid Tumors ◽

Prospective Observational Study ◽

Cost Savings ◽

Primary Prophylaxis ◽

Granulocyte Colony Stimulating Factor ◽

Substantial Cost ◽

Prescription Pattern ◽

Study Population ◽

Stimulating Factor

Introduction Febrile neutropenia (FN) is one of the dose-limiting adverse effects of chemotherapy. Granulocyte-Colony Stimulating Factors (G-CSFs) minimize the incidence of FN and reduce the risk of neutropenia complications. This study was conducted to address the prescription pattern of G-CSF for primary prophylaxis of FN during the first cycle of chemotherapy in solid tumors. Method This prospective observational study was done to investigate the G-CSF prescription pattern in patients receiving the first cycle of chemotherapy for solid tumors and compare it with the NCCN guideline recommendations. Result Based on the guideline, prophylactic G-CSF administration was indicated in 26 of the 96 patients (27.1%) and all of them received G-CSF. On the other hand, 70 patients (72.9%) did not meet the guideline criteria for prophylaxis, but 60 (62.5%) of them received G-CSF. Seven doses of pegfilgrastim and 165 doses of filgrastim were used inappropriately in the study population, which was associated with an economic burden of about 224.7 million IRR (5350 USD). Conclusion Taken together, inconsistencies with the guideline were observed in this prospective evaluation, suggesting that submitting rationalized policies to decrease G-CSF prescription, especially in patients with a lower or intermediate FN risk, yields substantial cost savings.

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