Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses

2015 ◽  
Vol 22 (3) ◽  
pp. 203-213 ◽  
Author(s):  
Arrigo F. G. Cicero ◽  
Alessandro Colletti
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Meta Analyses

scholarly journals Fixed-Dose Triple Combination of Antihypertensive Drugs Improves Blood Pressure Control: From Clinical Trials to Clinical Practice

2017 ◽  
Vol 34 (4) ◽  
pp. 975-985 ◽  
Author(s):  
Alberto Mazza ◽  
Salvatore Lenti ◽  
Laura Schiavon ◽  
Antonella Paola Sacco ◽  
Fabio Dell’Avvocata ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
Clinical Practice ◽  
Blood Pressure Control ◽  
Antihypertensive Drugs ◽  
Pressure Control ◽  
Fixed Dose ◽  
Triple Combination

scholarly journals How to conduct meta-analysis: a basic tutorial

2017 ◽  
Author(s):  
Arindam Basu
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Blood Pressure Control ◽  
Meta Analysis ◽  
Pressure Control ◽  
Restricted Diet ◽  
Summary Estimate ◽  
Meta Analyses ◽  
Key Steps ◽  
Published Paper

Meta analysis refers to a process of integration of the results of many studies to arrive at evidence syn- thesis. Meta analysis is similar to systematic review; however, in addition to narrative summary that is conducted in systematic review, in meta analysis, the analysts also numerically pool the results of the studies and arrive at a summary estimate. In this paper, we discuss the key steps of conducting a meta analysis. We will discuss the steps of a simple meta-analysis with a demonstration of the key steps based on a published paper on meta-analysis and systematic review of the effectiveness of salt restricted diet on blood pressure control. This paper is a basic introduction to the process of meta-analysis. In subsequent papers in this series, we will show how you can conduct meta-analysis of diagnostic and screening studies, network meta analyses, and those of diagnostic and screening studies.

scholarly journals Meta-analysis of pharmacist-led and pharmacist-physician intervention on blood pressure control

2021 ◽  
Vol 15 (3) ◽  
Author(s):  
Merve Memisoglu ◽  
Yusuf Çelik
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Impact Analysis ◽  
Patient Adherence ◽  
Meta Analysis ◽  
Pressure Control ◽  
Cochrane Library ◽  
Holistic View ◽  
Meta Analyses ◽  
The Impact

Effective intervention is a significant component in the improvement of blood pressure control and patient adherence. Blood pressure control includes different self-monitoring techniques, mobile health monitoring, or healthcare professionals’ interventions. This study aims to compare, analyze, and interpret the effectiveness of pharmacist-physician collaboration and pharmacist- led interventions. Meta-analysis was performed using MEDLINE via PubMed, EMBASE, EBSCO, Web of Science, Scopus, and the Cochrane Library databases between 2008-2018. Of the 51 relevant systematic reviews identified, 15 were of sufficient quality and included in the data synthesis. The breakdown of the 15 included 7 (n=2026) pharmacist and 8 pharmacist-physician interventions (n=2361). The impact of pharmacist-physician collaboration and pharmacist-led interventions on Systolic Blood Pressure was –8.22 (–11.01; –5.42) (P<0.01) and –7.68 (–9.30; –6.06) (P=0.35), respectively. On the other hand, similar correlation for Diastolic Blood Pressure for the impact of pharmacist-physician collaboration and pharmacist-led interventions was –3.55 (–4.54; –2.55) (P=0.49) and –2.58 (–3.76; –1.39) (P=0.24), respectively. These results suggest that both interventions are effective for blood pressure control. However, when two meta-analyses were compared, it was found that pharmacist-physician collaboration was more effective than pharmacist-led interventions. This finding highlights the importance of multidisciplinary approaches during blood pressure control procedures. When a holistic view is considered; especially cost-effectiveness, future studies must be diversified to encompass a broader context and impact analysis.

scholarly journals How to conduct meta-analysis: a basic tutorial

2017 ◽  
Author(s):  
Arindam Basu
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Blood Pressure Control ◽  
Meta Analysis ◽  
Pressure Control ◽  
Restricted Diet ◽  
Summary Estimate ◽  
Meta Analyses ◽  
Key Steps ◽  
Published Paper

Meta analysis refers to a process of integration of the results of many studies to arrive at evidence syn- thesis. Meta analysis is similar to systematic review; however, in addition to narrative summary that is conducted in systematic review, in meta analysis, the analysts also numerically pool the results of the studies and arrive at a summary estimate. In this paper, we discuss the key steps of conducting a meta analysis. We will discuss the steps of a simple meta-analysis with a demonstration of the key steps based on a published paper on meta-analysis and systematic review of the effectiveness of salt restricted diet on blood pressure control. This paper is a basic introduction to the process of meta-analysis. In subsequent papers in this series, we will show how you can conduct meta-analysis of diagnostic and screening studies, network meta analyses, and those of diagnostic and screening studies.

Hypertension and Endstage Renal Disease

1994 ◽  
Vol 28 (3) ◽  
pp. 359-366 ◽  
Author(s):  
Thomas E.R. Brown ◽  
Barry L. Carter
Keyword(s):  
Blood Pressure ◽  
Clinical Trials ◽  
Renal Insufficiency ◽  
Renal Disease ◽  
Blood Pressure Control ◽  
English Language ◽  
Antihypertensive Agents ◽  
Pressure Control ◽  
Annual Data ◽  
Endstage Renal Disease

OBJECTIVE: To review current literature regarding the development of hypertensive renal disease, its epidemiology, and its pathophysiology. This review focuses on strategies to slow or halt the progression of endstage renal disease (ESRD) in hypertension, including the role of blood pressure control, different types of antihypertensive agents, early treatment, and dietary considerations. DATA SOURCES: Information was retrieved from searching the MEDLINE database for articles consisting of epidemiologic studies, clinical studies, and review articles pertaining to hypertension and ESRD. Information also was obtained from the US Renal Data System annual data reports. STUDY SELECTION: Emphasis was placed on clinical trials in the English language addressing issues in hypertension and ESRD. Clinical trials reporting relationships between blood pressure control and ESRD, as well as those comparing different antihypertensive agents, were evaluated. DATA EXTRACTION: The methodology and results from clinical trials were evaluated. Studies were assessed according to the measures of renal function used, baseline data collected, degree of blood pressure control, and antihypertensive therapy. DATA SYNTHESIS: Clinical trials including patients with essential hypertension, diabetes mellitus, and renal insufficiency of various etiologies were evaluated. The recommendations from these evaluations were based on study design and the types of populations used (i.e., blacks vs. whites, diabetics vs. nondiabetics). CONCLUSIONS: Blood pressure control is currently the most important strategy to slow or halt the progression of renal insufficiency in hypertensive individuals. Whether specific antihypertensives are renal protective is still controversial, but results from clinical trials are promising.

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