Low-carbon steel Q235B was widely used in low or middle pressure equipments, which were not only withstanding the corrosive effect of the environment or medium, but also the high stress in service processes. In this paper, acetic acid accelerated corrosion test of low-carbon steel Q235B under the action of various stress levels was conducted, and its pitting corrosion behavior was studied by corrosion morphology, pitting corrosion parameters, scanning electron microscope (SEM) and energy disperse spectroscopy (EDS). The results showed that, the degree of pitting corrosion of low carbon steel Q235B with stress was more serious than that of non-stress. And the corrosion started from grain boundary, which was corroded before grain itself, and then grains fell off or dissolved. Furthermore, it would have the tendency of deep hole corrosion with stress, which was more of a threat to the structural safety of pressure vessels.