New Onset Ocular Myasthenia Gravis After Pembrolizumab Therapy: a Case Report

2021 ◽  
Author(s):  
Samantha Anne S. Gutierrez ◽  
Ludwig F. Damian
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
New Onset

scholarly journals New onset of ocular myasthenia gravis in a patient with COVID-19: a novel case report and literature review

2020 ◽  
Author(s):  
Shitiz Sriwastava ◽  
Medha Tandon ◽  
Saurabh Kataria ◽  
Maha Daimee ◽  
Shumaila Sultan
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Myasthenia Gravis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
New Onset

Tobramycine eye drops and ocular myasthenia gravis reactivation: A case report

Therapies ◽  
2020 ◽  
Author(s):  
Claire de Canecaude ◽  
Christophe Gazagne ◽  
Magali Paraire ◽  
Geneviève Durrieu
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Eye Drops ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

scholarly journals Miastenia Gravis Okular Juvenil: Laporan Kasus

2021 ◽  
Vol 1 (1) ◽  
pp. 39-52
Author(s):  
Fikta Zakia Nurfaizah ◽  
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Case Reports ◽  
Test Results ◽  
Upper Eyelid ◽  
Ocular Myasthenia ◽  
Confirmation Test ◽  
Ocular Myasthenia Gravis ◽  
Relevant Case ◽  
The Subject

Abstract Purpose: This study aimed to summarize the general history, physical exam findings, confirmation test, and treatment of a patient with juvenile ocular myasthenia gravis. Research Methodology: This article is a pediatric RSUD Abdoel Moeloek Lampung case report in April 2021. The subject of the case is a 3-year-old girl who is hospitalized in the hospital ward with juvenile ocular myasthenia gravis. Result: A 3-year-old girl, an inpatient in the Pediatric Ward, RSUD Abdoel Moeloek Lampung, with complaints of decreased left upper eyelid since three months ago. On physical examination, there was ptosis of the left superior palpebra. Prostigmine test was performed on day 2 of treatment in patients with positive test results. The patient was clinically diagnosed with “Juvenile Ocular Myasthenia Gravis.” Management of the patient during treatment was the injection of methylprednisolone 10 mg/12 hours and neostigmine orally 2.5 mg/8 hours. Limitations: This case report is limited to juvenile ocular myasthenia gravis cases with a scarce number of cases and rare cases in children. Contribution: This case report can be helpful in medical education or used as a reference in making relevant case reports and can be applied in the hospital area when there are cases of juvenile ocular myasthenia gravis.

scholarly journals Seeking spark- ocular myasthenia gravis in a juvenile – an Indian case report

2020 ◽  
Vol 5 (7) ◽  
pp. 190-193
Author(s):  
Dr. Usha BR. ◽  
◽  
Dr. Nandhini K ◽  
Dr. Chaitra MC ◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Neuromuscular Junction ◽  
Myasthenia Gravis ◽  
Autoimmune Disorder ◽  
Bilateral Ptosis ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
History Of ◽  
High Index Of Suspicion

Myasthenia gravis (MG) is a rare autoimmune disorder affecting neuromuscular junction by muscleweakness. Myasthenia gravis can be generalized or localized as ocular myasthenia gravis. Casepresentation: We report an 8-year-old boy who presented with 10 days history of drooping of botheyelids and 8 days history of diplopia. Examination revealed bilateral ptosis. A diagnosis of JuvenileOcular Myasthenia gravis was made when symptoms improved with intramuscular Edrophoniumadministration. He was commenced on oral Neostigmine at a dose of 2mg/Kg/ day,4 hourly individed doses and is on regular follow up and had a good response. Conclusion: Ocular Myastheniagravis (OMG) is a rare disease in itself. A high index of suspicion is required in a juvenile as it iseven rarer.

scholarly journals Ice-on-Eyes Test in the Diagnosis of Myasthenia Gravis

2012 ◽  
Vol 2 (2) ◽  
pp. 92-93
Author(s):  
Nazmul Haque ◽  
Rukhsana Parvin ◽  
Naser Ahmed ◽  
AKM Rafique Uddin
Keyword(s):  
Case Report ◽  
Cost Effectiveness ◽  
Myasthenia Gravis ◽  
Neuromuscular Transmission ◽  
Muscle Membrane ◽  
College Hospital ◽  
Medical College ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis ◽  
Tensilon Test

Myasthenia gravis is the most frequent autoimmune neuromuscular transmission disorder  with incidence of 2-20 patients per million. Its pathophysiology is autoimmune, with  acetylcholine receptor auto antibodies damaging the post-synaptic fold at the muscle  membrane. The diagnostic confirmation of myasthenia gravis is often challenging. Ice-oneyes  test can be used to diagnose this disease for its simplicity, safety and cost-effectiveness. Here we report a case of myasthenia gravis in Enam Medical College Hospital, Savar, Dhaka where ice-on-eyes test was done with improvement of ptosis of the patient. Aim of this case  report is to make aware our physicians to apply this simple bed side test instead of common  traditional edrophonium (tensilon test) test for confirmation of the diagnosis of ocular myasthenia gravis. DOI: http://dx.doi.org/10.3329/jemc.v2i2.12845 J Enam Med Col 2012; 2(2): 92-93  

scholarly journals Transient acetylcholine receptor-related myasthenia gravis, post multisystem inflammatory syndrome in children (MIS-C) temporally associated with COVID-19 infection

2021 ◽  
Vol 14 (8) ◽  
pp. e244102
Author(s):  
Farida Essajee ◽  
Juanita Lishman ◽  
Regan Solomons ◽  
Deepthi Raju Abraham ◽  
Pierre Goussard ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
Unique Case ◽  
Ocular Myasthenia ◽  
Cold Compression ◽  
Ocular Myasthenia Gravis ◽  
Antibody Positivity ◽  
Inflammatory Syndrome ◽  
Ocular Signs ◽  
New Onset

We report on a unique case of a 7-year-old girl with new onset ocular myasthenia gravis shortly after recovery from multisystem inflammatory syndrome in children (MIS-C) temporally associated with SARS-CoV-2 infection. The diagnosis of myasthenia gravis was based on suggestive symptoms of fatigable bilateral orbital ptosis, diplopia, positive ocular cold compression test and serum acetylcholine receptor antibody positivity, as well as a favourable treatment response to pyridostigmine. The addition of corticosteroids and methotrexate resulted in complete resolution of the ocular signs.

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