Effects of left ventricular assist for cardiogenic shock on cardiac function and organ blood flow distribution

1990 ◽  
Vol 50 (3) ◽  
pp. 374-383 ◽  
Author(s):  
S. Sukehiro ◽  
W. Flameng
2016 ◽  
Vol 2016 ◽  
pp. 1-1 ◽  
Author(s):  
Paloma Morillas-Sendín ◽  
Emilio Delgado-Baeza ◽  
María Jesús Delgado-Martos ◽  
Mónica Barranco ◽  
Juan Francisco Del Cañizo ◽  
...  

1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
P. F. Wouters ◽  
T. Möllhoff ◽  
U. Mees ◽  
H. Van Aken ◽  
W. Flameng

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Paloma Morillas-Sendín ◽  
Emilio Delgado-Baeza ◽  
María Jesús Delgado-Martos ◽  
Mónica Barranco ◽  
Juan Francisco del Cañizo ◽  
...  

The aim of this study was to assess the effect of sevoflurane and propofol on organ blood flow in a porcine model with a left ventricular assist device (LVAD). Ten healthy minipigs were divided into 2 groups (5 per group) according to the anesthetic received (sevoflurane or propofol). A Biomedicus centrifugal pump was implanted. Organ blood flow (measured using colored microspheres), markers of tissue injury, and hemodynamic parameters were assessed at baseline (pump off) and after 30 minutes of partial support. Blood flow was significantly higher in the brain (both frontal lobes), heart (both ventricles), and liver after 30 minutes in the sevoflurane group, although no significant differences were recorded for the lung, kidney, or ileum. Serum levels of alanine aminotransferase and total bilirubin were significantly higher after 30 minutes in the propofol group, although no significant differences were detected between the groups for other parameters of liver function, kidney function, or lactic acid levels. The hemodynamic parameters were similar in both groups. We demonstrated that, compared with propofol, sevoflurane increases blood flow in the brain, liver, and heart after implantation of an LVAD under conditions of partial support.


2010 ◽  
Vol 5 (1) ◽  
pp. 16
Author(s):  
Aman Ali ◽  
Timothy A Sanborn ◽  
◽  

Among patients with acute myocardial infarction (AMI), those in cardiogenic shock have the highest mortality rate. Early revascularisation with primary percutaneous intervention or coronary artery bypass surgery has decreased the mortality rate of patients in cardiogenic shock, but it remains high. The conventional treatment of haemodynamic instability has been the use of the intra-aortic balloon pump (IABP); however, the IABP may not give adequate support to patients with severe left ventricular dysfunction. Recent advances in percutaneous left ventricular assist devices, specifically the TandemHeart and Impella LP 2.5, have shown improved haemodynamic support compared with the IABP. This article provides an overview of the use of percutaneous left ventricular assist devices to treat patients presenting with cardiogenic shock after acute MI.


2014 ◽  
Vol 1 (2) ◽  
pp. K13-K16
Author(s):  
Tigran Khachatryan ◽  
Roy Beigel ◽  
Reza Arsanjani ◽  
Robert J Siegel

Summary We describe a case of a 58-year-old man with cardiogenic shock who underwent triple vessel coronary artery bypass and a left ventricular assist device (LVAD) implantation. His course was complicated by stroke, worsening mitral regurgitation, aortic regurgitation, and multiple cardiac thrombi while on the device. We provide the details of the patient's hospital course, management, and echocardiographic findings. We also discuss the utility of echocardiography before LVAD insertion and its role for continued monitoring after insertion. Learning points Ventricular assist devices (VADs) are used as bridge to decision, transplant, recovery, or destination therapy in patients with advanced heart failure and cardiogenic shock. VADs improve survival and the quality of life but have significant associated complications. Echocardiography plays an essential role before VAD insertion and for postoperative cardiac monitoring. Information provided by echocardiography is used in device selection, consideration for corrective surgical interventions, and device explantation.


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