Early changes in hepatic redox homeostasis following treatment with a single dose of valproic acid

1990 ◽  
Vol 40 (3) ◽  
pp. 589-593 ◽  
Author(s):  
Dita Cotariu ◽  
Sandra Evans ◽  
Jacob L. Zaidman ◽  
Ora Marcus
Keyword(s):  
Valproic Acid ◽  
Single Dose ◽  
Redox Homeostasis

A Single Dose of Valproic Acid Improves Neurologic Recovery and Decreases Brain Lesion Size in Swine Subjected to an Isolated Traumatic Brain Injury

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Glenn K. Wakam ◽  
Ben E. Biesterveld ◽  
Manjunath P. Pai ◽  
Michael T. Kemp ◽  
Rachel L. O’Connell ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Single Dose ◽  
Brain Injury ◽  
Brain Lesion ◽  
Lesion Size ◽  
Neurologic Recovery

Pharmacokinetics of valproic acid in volunteers after a single dose study

1985 ◽  
Vol 6 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Meir Bialer ◽  
Ziad Hussein ◽  
Itamar Raz ◽  
Oded Abramsky ◽  
Yuval Herishanu ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Single Dose ◽  
Single Dose Study ◽  
Dose Study

Sex related differences on valproic acid pharmacokinetics after oral single dose

2013 ◽  
Vol 40 (4) ◽  
pp. 479-486 ◽  
Author(s):  
Manuel Ibarra ◽  
Marta Vázquez ◽  
Pietro Fagiolino ◽  
Hartmut Derendorf
Keyword(s):  
Valproic Acid ◽  
Single Dose

scholarly journals Effects of single-dose antipurinergic therapy on behavioral and molecular alterations in the valproic acid-induced animal model of autism

2020 ◽  
Vol 167 ◽  
pp. 107930 ◽  
Author(s):  
Mauro Mozael Hirsch ◽  
Iohanna Deckmann ◽  
Júlio Santos-Terra ◽  
Gabriela Zanotto Staevie ◽  
Mellanie Fontes-Dutra ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Animal Model ◽  
Single Dose ◽  
Molecular Alterations

Early Structural and Functional Changes in Liver of Rats Treated with a Single Dose of Valproic Acid

Hepatology ◽  
1984 ◽  
Vol 4 (6) ◽  
pp. 1159-1166 ◽  
Author(s):  
Anne Marie Jezequel ◽  
Patrizia Bonazzi ◽  
Giuseppe Novelli ◽  
Cinzia Venturini ◽  
Francesco Orlandi
Keyword(s):  
Valproic Acid ◽  
Single Dose ◽  
Functional Changes

A cool side effect of valproic acid administration: Single dose-induced hypothermia

2018 ◽  
Vol 36 (11) ◽  
pp. 2129.e3-2129.e4 ◽  
Author(s):  
Nicholas Servati ◽  
James Priano ◽  
Jason Vilar ◽  
Jason Schiel
Keyword(s):  
Valproic Acid ◽  
Single Dose ◽  
Side Effect ◽  
Induced Hypothermia ◽  
Acid Administration

The Response of Testes Cells to Low Level, Single dose Helium Particle Irradiation

1982 ◽  
Vol 40 ◽  
pp. 252-253
Author(s):  
D.E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
J. Stevenson ◽  
S. Black ◽  
...  
Keyword(s):  
Stem Cell ◽  
Single Dose ◽  
B Cell ◽  
Cell Survival ◽  
Spermatogonial Stem Cell ◽  
Low Doses ◽  
Particle Irradiation ◽  
Stem Cell Survival ◽  
Irradiation Injury ◽  
Radio Sensitivity

Spermatogonial stem-cell survival after irradiation injury has been studied in rodents by histological counts of surviving cells. Many studies, including previous work from our laboratory, show that the spermatogonial population demonstrates a heterogeneous response to irradiation. The spermatogonia increase in radio-sensitivity as differentiation proceeds through the sequence As - Apr - A1 - A2 - A3 - A4 - In - B. The stem (As) cell is the most resistant and the B cell is the most sensitive. The purpose of this work is to investigate the response of spermatogonial cell to low doses (less than 10 0 rads) of helium particle irradiation.

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