Event-related potentials in substance abusers after long-term abstinence

1992 ◽  
Vol 31 (5) ◽  
pp. 145
Keyword(s):  
Substance Abusers ◽  
Event Related Potentials ◽  
Related Potentials

EVENT-RELATED POTENTIALS IN SUBSTANCE ABUSERS AFTER LONG TERM ABSTINENCE

1992 ◽  
Vol 15 ◽  
pp. 121B
Author(s):  
M. Branchey ◽  
L. Buydens-Branchey ◽  
T. B. Horvath
Keyword(s):  
Substance Abusers ◽  
Event Related Potentials ◽  
Related Potentials

Event-Related Potentials in Substance-Abusing Individuals After Long-Term Abstinence

1993 ◽  
Vol 2 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Marc H. Branchey ◽  
Laure Buydens-Branchey ◽  
Thomas B. Horvath
Keyword(s):  
Event Related Potentials ◽  
Substance Abusing ◽  
Related Potentials

Event-Related Potentials in Substance-Abusing Individuals After Long-Term Abstinence

1993 ◽  
Vol 2 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Marc H. Branchey ◽  
Laure Buydens-Branchey ◽  
Thomas B. Horvath
Keyword(s):  
Event Related Potentials ◽  
Substance Abusing ◽  
Related Potentials

Cognitive Event-Related Potentials–The P300 Wave Is a Prognostic Factor of Long-Term Disability Progression in Patients With Multiple Sclerosis

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jarmila Szilasiová ◽  
Jaroslav Rosenberger ◽  
Pavol Mikula ◽  
Marianna Vitková ◽  
Miriam Fedičová ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Prognostic Factor ◽  
Event Related Potentials ◽  
Disability Progression ◽  
P300 Wave ◽  
Related Potentials ◽  
Cognitive Event

Neurophysiological Correlates of Nociceptive Heterosynaptic Long-Term Potentiation in Humans

2010 ◽  
Vol 103 (4) ◽  
pp. 2107-2113 ◽  
Author(s):  
Emanuel N. van den Broeke ◽  
Clementina M. van Rijn ◽  
José A. Biurrun Manresa ◽  
Ole K. Andersen ◽  
Lars Arendt-Nielsen ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Pain Perception ◽  
Event Related Potentials ◽  
Long Term Potentiation ◽  
P300 Amplitude ◽  
Experimental Conditions ◽  
Term Potentiation ◽  
Before And After ◽  
Related Potentials

Long-term potentiation (LTP) is a cellular model of synaptic plasticity and reflects an increase of synaptic strength. LTP is also present in the nociceptive system and is believed to be one of the key mechanisms involved in the manifestations of chronic pain. LTP manifested as an increased response in pain perception can be induced in humans using high-frequency electrical stimulation (HFS). The aim of this study was to induce spinal heterosynaptic LTP using HFS and investigate its heterotopic effects on event-related potentials (ERPs) to repeated nonpainful cutaneous stimuli as a possible electrophysiological cortical correlate of sensitization. Twenty-two healthy subjects were randomly assigned to one of the two experimental conditions: HFS and control stimulation. Before and after the stimulation, both conditions received heterotopic mechanical (pinprick) and paired nonpainful electrical test stimuli to quantify and confirm the effects of HFS on the behavioral level. ERPs to paired nonpainful electrical stimulation were measured simultaneously. Conditioning HFS resulted in significant heterotopic effects after 30 min, including increased perceived intensity in response to (pinprick) mechanical and paired nonpainful electrical stimulation compared with control. The paired nonpainful electrical stimuli were accompanied by significantly enhanced responses regarding the ERP N1-P2 peak-to-peak and P300 amplitude compared with control. These findings suggest that HFS is capable of producing heterosynaptic spinal LTP that can be measured not only behaviorally but also using ERPs.

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