Abnormal expression of surface immunoglobulin isotypes on antigen-binding B lymphocytes from mice tolerant to trinitrophenyl determinants

1987 ◽  
Vol 107 (2) ◽  
pp. 408-416
Author(s):  
Richard D. Brasington ◽  
Mary E. Morton ◽  
Cynthia E. Baumgartner ◽  
Robert F. Ashman
Keyword(s):  
B Lymphocytes ◽  
Antigen Binding ◽  
Surface Immunoglobulin ◽  
Abnormal Expression ◽  
Immunoglobulin Isotypes

scholarly journals Cell surface immunoglobulin. XVIII. Functional differences of B lymphocytes bearing different surface immunoglobulin isotypes.

1976 ◽  
Vol 143 (5) ◽  
pp. 1055-1065 ◽  
Author(s):  
E S Vitetta ◽  
J Forman ◽  
J R Kettman
Keyword(s):  
Cell Surface ◽  
B Cell ◽  
B Lymphocytes ◽  
Surface Immunoglobulin ◽  
Functional Differences ◽  
Immunoglobulin Isotypes ◽  
Cell Mitogen

Three populations of murine splenic B lymphocytes have been characterized previously (6, 7, 9) as those bearing only IgM, those bearing only IgD, and a population bearing both isotopes. These studies were designed to test the response of the IgM+ cells (IgM-only or IgM plus IgD) vs. the IgD-only cells to the B-cell mitogen, lipopolysaccharide. Results that after 1-4 days of culture, in the presence of mitogen, the IgM+ cells enlarge and elaborate an IgM polyclonal response. The IgD-only cells, in contrast, do not exhibit an IgM polyclonal response, but instead undergo blastogenesis and proliferation.

Polyclonal activation of B lymphocytes during experimental infection with Schistosoma mansoni

Parasitology ◽  
1990 ◽  
Vol 100 (1) ◽  
pp. 83-91 ◽  
Author(s):  
L. M. Lopes ◽  
M. A. C. Pereira ◽  
S. E. Gerken ◽  
N. Vaz
Keyword(s):  
Schistosoma Mansoni ◽  
B Lymphocytes ◽  
Experimental Infection ◽  
Adoptive Transfer ◽  
Cell Activation ◽  
Protein A ◽  
B Cell Activation ◽  
Spleen Cells ◽  
Polyclonal Activation ◽  
Immunoglobulin Isotypes

SummaryA significant polyclonal activation of B lymphocytes was observed during experimental infection of C57BL/10J mice with Schistosoma mansoni. The isotypic pattern of this expansion, assessed by the Protein-A plaque-forming cell method, was compared with and found to differ from those occurring after infection by Trypanosoma cruzi or injection of bacterial LPS. In the infection of S. mansoni an early expansion of most immunoglobulin isotypes occurs together with a late, sustained expansion of IgG1-secreting cells. High levels of polyclonal B cell activation were observed after adoptive transfer of spleen cells from infected mice to isogenic recipients pre-treated with hydroxyurea.

Surface immunoglobulin ligands and cytokines differentially affect proliferation and antibody production by human CD5+ and CD5− B lymphocytes

1990 ◽  
Vol 2 (7) ◽  
pp. 603-614 ◽  
Author(s):  
Yasushi Nawata ◽  
Alan M. Stall ◽  
Leonore A. Herzenberg ◽  
Elsie M. Eugui ◽  
Anthony C. Allison
Keyword(s):  
B Lymphocytes ◽  
Antibody Production ◽  
Surface Immunoglobulin

Visualization of surface immunoglobulin of human B lymphocytes using microsphere—Immunoglobulin conjugate in Giemsa-stained preparations

1977 ◽  
Vol 8 (1) ◽  
pp. 51-63 ◽  
Author(s):  
I.L. Gordon ◽  
R.J. Lukes ◽  
R.L. O'Brien ◽  
J.W. Parker ◽  
A. Rembaum ◽  
...  
Keyword(s):  
B Lymphocytes ◽  
Surface Immunoglobulin
Sign in / Sign up

Export Citation Format

Share Document