Bidirectional response of the GABA agonist, sodium valproate, on event related potentials of healthy volunteers

1993 ◽  
Vol 87 (2) ◽  
pp. S57
Author(s):  
M. Urasaki ◽  
R. Shiroma ◽  
H. Ohta ◽  
K. Fukao ◽  
Y. Hirayasu ◽  
...  
2020 ◽  
Vol 16 (2) ◽  
pp. 138-152
Author(s):  
Bingren Zhang ◽  
Chu Wang ◽  
Chanchan Shen ◽  
Wei Wang

Background: Responses to external emotional-stimuli or their transitions might help to elucidate the scientific background and assist the clinical management of psychiatric problems, but pure emotional-materials and their utilization at different levels of neurophysiological processing are few. Objective: We aimed to describe the responses at central and peripheral levels in healthy volunteers and psychiatric patients when facing external emotions and their transitions. Methods: Using pictures and sounds with pure emotions of Disgust, Erotica, Fear, Happiness, Neutral, and Sadness or their transitions as stimuli, we have developed a series of non-invasive techniques, i.e., the event-related potentials, functional magnetic resonance imaging, excitatory and inhibitory brainstem reflexes, and polygraph, to assess different levels of neurophysiological responses in different populations. Results: Sample outcomes on various conditions were specific and distinguishable at cortical to peripheral levels in bipolar I and II disorder patients compared to healthy volunteers. Conclusions: Methodologically, designs with these pure emotions and their transitions are applicable, and results per se are specifically interpretable in patients with emotion-related problems.


2002 ◽  
Vol 17 (6) ◽  
pp. 285-291 ◽  
Author(s):  
Verner J. Knott ◽  
Colleen Mahoney ◽  
Tove Gunnarsson ◽  
Jacques Bradwejn ◽  
Jakov Shlik

1991 ◽  
Vol 9 (1) ◽  
pp. 33-40
Author(s):  
Rie Akaho ◽  
Ikuo Ichikawa ◽  
Masamichi Suzuki ◽  
Kazuyuki Nakagome ◽  
Hirohumi Watanabe ◽  
...  

2016 ◽  
Vol 623 ◽  
pp. 36-41 ◽  
Author(s):  
Molly Hyde ◽  
Joëlle Choueiry ◽  
Dylan Smith ◽  
Sara de la Salle ◽  
Renee Nelson ◽  
...  

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