Development of oral lesions in erythema multiforme exudativum

1967 ◽  
Vol 24 (6) ◽  
pp. 808-816 ◽  
Author(s):  
James W. Wooten ◽  
Harry I. Katz ◽  
Seymour Hoffman ◽  
Joseph F. Link
2021 ◽  
Author(s):  
Yaser Fathi ◽  
Elaheh Ghasemzadeh Hoseini ◽  
Reza Mottaghi

Background: SARS-CoV-2, is followed by several manifestations, such as fever, cough, respiratory distress syndrome and mucocutaneous lesions such as papules, urticaria, vasculitic purpura and erythema multiform. Case: A 22-year old woman was diagnosed with COVID-19. Considering the skin and oral lesions, erythema multiform was suggested as the most likely diagnosis. Oral valaciclovir was administered. Discussion: Erythema multiforme were reported in some patients with COVID-19. Its pathophysiology is not yet completely understood, but it seems there is a lymphocyte-mediated hypersensitivity reaction to SARS-CoV-2 antigens presenting in the skin. Conclusion: Mucocutaneous and oral lesions might be the first manifestations of COVID-19. Therefore, during the pandemic, it is prudent to consider this virus as a differential diagnosis once we encounter oral ulceration.


2003 ◽  
Vol 27 (1) ◽  
pp. 71-76 ◽  
Author(s):  
K. Donta –Bakoyianni ◽  
A. Mitsea ◽  
K. Deodoropoulou-Papadimitriou

Erythema Multiforme (EM) is a rare mucocutaneous disease with a variety of clinical manifestations. EM it was recognized in the early 1800's, and still the etiology is unknown. It has been recently suggested erythema multiforme (EM) major and Stevens-Johnson Syndrome (SJS) could be separated as two distinct clinical disorders with similar mucosal erosions, but different patterns of cutaneous lesions. In particular SJS should be used for a syndrome characterized by mucous membrane erosions and widespread small blisters that appear on erythematous or purpuric maculae, which are different from classic targets. In SJS mouth, eyes, skin, genitalia and occasionally the esophagus and respiratory track may be affected. Oral lesions may cause severe pain and usually lips may become encrusted. Concerning ocular involvement, if there is conjunctivitis or uveitis this may lead to scarring and blindness. Also, the course of disease and the prognosis are in most cases severe.


1952 ◽  
Vol 5 (11) ◽  
pp. 1207-1212 ◽  
Author(s):  
George J. Whinston

1995 ◽  
Vol 24 (1) ◽  
pp. 9-13 ◽  
Author(s):  
P. M. Farthing ◽  
P. Maragou ◽  
M. Coates ◽  
F. Tatnall ◽  
I. M. Leigh ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Zana Sllamniku Dalipi ◽  
Fatmir Dragidella ◽  
Donika Kastrati Dragidella

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a viral infection with multiorgan manifestations that may affect the oral mucosa. The full range of oral manifestations of COVID-19 are unknown, and there are limited reports describing the features of oral manifestations of COVID-19, including taste loss, oral lesions, and xerostomia. The aim of this study is to report a case of oral erythema multiforme (EM) manifesting as oral, lip, and skin lesions in a COVID-19 patient. The presence of oral lesions in the late stage of COVID-19 could be related to weak patient immunity or related therapies.


2018 ◽  
Vol 11 (1) ◽  
pp. 167-170
Author(s):  
Shamimul Hasan ◽  
Jogender Jangra ◽  
Priyadarshini Choudhary ◽  
Silpiranjan Mishra

Erythema multiforme (EM) is an acute, self-healing inflammatory mucocutaneous disorder which presents with diverse spectrum of cutaneous lesions, hence termed “multiforme”. Oral lesions are quite characteristic and manifest as rapidly rupturing vesicles & bullae forming ill-defined erosions and hemorrhagic encrusted lip lesions. Wide variety of triggering factors for EM have been documented in the literature, but history of prior herpes simplex virus (HS) infection is most widely accepted. Most other cases are seen after the intake of certain medications. EM has been chiefly divided into two main forms- EM minor and EM major. Steven Johnson syndrome & Toxic epidermal necrolysis (Lyell’s disease) are now considered as distinct clinical entities. EM has a self-limiting course and the lesions usually resolve within few weeks. Symptomatic management along with recognition and alteration of the alleged precipitating factors is usually sufficient in the majority of cases. However, in advanced lesions, steroid therapy may be helpful. This paper aims to present a recent update on Erythema Multiforme taking into account its etiopathogenesis, clinical and oral features, diagnostic aids and treatment protocols.


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