Early stages of newcastle disease virus-hela cell interaction: An electron microscopic study

Virology ◽  
1964 ◽  
Vol 23 (3) ◽  
pp. 370-380 ◽  
Author(s):  
Samuel C. Silverstein ◽  
Philip I. Marcus
1967 ◽  
Vol 2 (1) ◽  
pp. 71-76
Author(s):  
N. MEISELMAN ◽  
A. KOHN ◽  
D. DANON

Treatment of FL or Lu 106 epithelial cells with Newcastle disease virus (NDV) at an input multiplicity of 500 EID50 per cell induces in these cells the formation of polykaryocytes at the end of 2-3 h of contact. Electron micrographs of such NDV-treated monolayers after 2-10 min of incubation show the presence of virions adsorbed to the cell membranes, in vacuoles and with the viral envelope partly fused with the cell membrane. In polykaryocytes induced by NDV, remnants of cell membranes showing numerous breaks may still be present after 3 h.


animal ◽  
2012 ◽  
Vol 6 (8) ◽  
pp. 1246-1252 ◽  
Author(s):  
Q. Renli ◽  
S. Chao ◽  
Y. Jun ◽  
S. Chan ◽  
X. Yunfei

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