scholarly journals Inhibition of sheep vesicular gland oxygenase by unsaturated fatty acids from skin of essential fatty acid deficient rats

1974 ◽  
Vol 5 (3) ◽  
pp. 233-240 ◽  
Author(s):  
Vincent A. Ziboh ◽  
Jack Y. Vanderhoek ◽  
William E.M. Lands
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Unsaturated Fatty Acids ◽  
Essential Fatty Acid Deficient

Effects of essential fatty acid deficiency on rat adrenal composition and secretory activity

1959 ◽  
Vol 197 (4) ◽  
pp. 893-896 ◽  
Author(s):  
Takuya Hayashida ◽  
Oscar W. Portman
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Corn Oil ◽  
Essential Fatty Acids ◽  
Secretory Activity ◽  
Monounsaturated Fatty Acids ◽  
Essential Fatty Acid Deficient ◽  
Fatty Acid Deficiency

The effect of feeding diets deficient in essential fatty acids on the composition of adrenal lipids and on the secretory activity of adrenocortical hormones was studied. Rats which were fed diets devoid of fat had lower levels of tetraenoic and pentaenoic acids and higher levels of trienoic acids in both the total lipid and cholesterol ester fraction than did rats receiving a supplement of corn oil. There was a greater accumulation of cholesterol esterified with saturated and monounsaturated fatty acids in the adrenals of the rats fed essential fatty acid-deficient diets. The adrenals of the essential fatty acid-deficient rats secreted smaller quantities of steroid hormones in vitro under the stimulation of ACTH.

Absorption and metabolism of [3H]arachidonic and [14C]linoleic acid in essential fatty acid-deficient rats

1990 ◽  
Vol 259 (1) ◽  
pp. G116-G124 ◽  
Author(s):  
L. Hjelte ◽  
T. Melin ◽  
A. Nilsson ◽  
B. Strandvik
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Essential Fatty Acid ◽  
Mitochondrial Membrane ◽  
Inner Mitochondrial Membrane ◽  
Fecal Fat ◽  
Essential Fatty Acid Deficient ◽  
Drastic Increase ◽  
Fat Excretion

[3H]arachidonic acid (20:4) and [14C]linoleic acid (18:2) were fed in a triolein emulsion to essential fatty acid-deficient (EFAD) rats and to age-matched controls. Tissues were analyzed for radioactivity of different lipid classes after 1, 2, and 4 h. As in earlier studies [Nilsson and Melin. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 19): G612-G618, 1988], control rats retained more [3H]20:4 than [14C]18:2 in all organs except adipose tissue. In EFAD rats, recovery of [14C]18:2 was increased in small intestine, liver, heart, and kidneys. In comparison to controls, EFAD rats retained much more [14C]18:2 in phospholipids of these organs. The increase in the incorporation of both 3H and 14C into phosphatidylethanolamine was particularly pronounced. Another striking feature was the drastic increase in the retention after 4 h of 14C in cardiolipin, which is specifically located in the inner mitochondrial membrane. In contrast, incorporation of both 3H and 14C into phosphatidylinositol was decreased or unchanged in EFAD rats. Although fecal fat excretion was increased there was no evidence for a malabsorption or an increased retention in intestinal triacyglycerol of the radioactive fatty acids in EFAD rats. The proportion of [14C]18:2 that had been converted to [14C]20:4 was generally low but increased significantly with time in the liver and intestine of EFAD rats.

scholarly journals The influence of α-linolenic acid (18: 3ω3) on the metabolism of γ-linolenic acid (18: 3ω6) in the rat

1977 ◽  
Vol 38 (1) ◽  
pp. 137-140 ◽  
Author(s):  
A. G. Hassam
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Linolenic Acid ◽  
Essential Fatty Acid ◽  
List Type ◽  
Dietary Energy ◽  
Type Number ◽  
Essential Fatty Acid Deficient ◽  
Long Chain

1.Essential fatty acid-deficient rats were fed γ-linolenic acid (18:3ω6) at 2 % dietary energy and α-linolenic acid (18:3ω3) at 0, 1.6, 2.8 and 4.0 % of the dietary energy.2.18:3ω3 at 1.6% apparently inhibits the synthesis of the C20 and C22 ω6 long-chain polyunsaturated fatty acids (ω6 LC-PUFA) metabolized from 18:3ω6.3.However, increasing the dietary levels of 18:3ω3 from 1.6 to 4.0% has no further influence.4.The results suggest that dietary 18:3ω6 is an efficient precursor for the ω6 LC-PUFA synthesis even in the presence of 18:3ω3.

Sign in / Sign up

Export Citation Format

Share Document