R plasmid gene dosage effects in Escherichia coli K-12: Copy mutants of the R plasmid R1drd-19

Plasmid ◽  
1977 ◽  
Vol 1 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Bernt Eric Uhlin ◽  
Kurt Nordström
Keyword(s):  
Escherichia Coli ◽  
Gene Dosage ◽  
Plasmid Gene ◽  
Gene Dosage Effects ◽  
Dosage Effects ◽  
K 12

scholarly journals Application of hybrid plasmids carrying glycolysis genes to ATP production by Escherichia coli

1982 ◽  
Vol 152 (1) ◽  
pp. 98-103
Author(s):  
M Shimosaka ◽  
Y Fukuda ◽  
K Murata ◽  
A Kimura
Keyword(s):  
Escherichia Coli ◽  
Triosephosphate Isomerase ◽  
Gene Dosage ◽  
Transformed Cells ◽  
Structural Genes ◽  
Atp Production ◽  
E Coli ◽  
Gene Dosage Effects ◽  
Dosage Effects ◽  
Specific Activities

The closely linked structural genes of phosphofructokinase (pfkA) and triosephosphate isomerase (tpi) of Escherichia coli were separately cloned onto plasmid pBR322. By gene dosage effects, transformed cells of E. coli C600 with these pBR322 hybrid plasmids showed 7- and 16-fold increases in the specific activities of phosphofructokinase and triosephosphate isomerase, respectively, over the specific activities in C600. Dried preparations of E. coli cells dosed with these genes showed appreciably high ATP-regenerating activity.

scholarly journals Control of the tRNA-tufB operon in Escherichia coli. 1. rRNA gene dosage effects and growth-rate-dependent regulation

1988 ◽  
Vol 175 (2) ◽  
pp. 355-362 ◽  
Author(s):  
Joost H. M. DELFT ◽  
Hans M. VERBEEK ◽  
Paul J. JONG ◽  
Denise S. SCHMIDT ◽  
Anneke TALENS ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Growth Rate ◽  
Gene Dosage ◽  
Rrna Gene ◽  
Gene Dosage Effects ◽  
Rate Dependent ◽  
Dosage Effects

scholarly journals Gene dosage effects of the structural gene for a lipoprotein of the Escherichia coli outer membrane.

1978 ◽  
Vol 133 (1) ◽  
pp. 81-84 ◽  
Author(s):  
N R Movva ◽  
E Katz ◽  
P L Asdourian ◽  
Y Hirota ◽  
M Inouye
Keyword(s):  
Escherichia Coli ◽  
Outer Membrane ◽  
Structural Gene ◽  
Gene Dosage ◽  
Gene Dosage Effects ◽  
Dosage Effects

scholarly journals Genetics advances and learning disability

2000 ◽  
Vol 176 (1) ◽  
pp. 12-19 ◽  
Author(s):  
Walter J. Muir
Keyword(s):  
Learning Disability ◽  
Gene Dosage ◽  
Genetic Disorders ◽  
Molecular Medicine ◽  
Gene Dosage Effects ◽  
Dosage Effects ◽  
Rapid Changes ◽  
Basic Understanding ◽  
Genetic Mechanisms ◽  
Dynamic Mutations

BackgroundMedicine is rapidly becoming molecular medicine, and little escapes the grasp of modern genetics. Most disorders associated with learning disability have at least a genetic component influencing their expression; in many disorders, disturbances of genetic mechanisms play a pivotal role.AimsDynamic mutations, imprinting mechanisms and gene-dosage effects are explained with reference to genetic disorders that lead to learning disability.MethodA review of recent important studies in the genetics of learning disability.ResultsA host of new genetic connections to conditions associated with learning disability have been made.ConclusionsA basic understanding of these genetic connections is important for all learning disability psychiatrists if they are to follow the rapid changes – already beginning to influence our practice – that hold immense promise for the future.

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