Contribution to the control of inactivated human influenza vaccines with the single radial diffusion method (SRD): Routine check, industrial super vision and vaccine standardisation

1980 ◽  
Vol 3 (1-2) ◽  
pp. 207-218 ◽  
Author(s):  
G Larbaigt ◽  
N Gibelin ◽  
B Montagnon ◽  
B Fanget ◽  
J Zayet
Keyword(s):  
Radial Diffusion ◽  
Influenza Vaccines ◽  
Diffusion Method ◽  
Human Influenza

Human influenza vaccines and assessment of immunogenicity

2010 ◽  
Vol 9 (12) ◽  
pp. 1423-1439 ◽  
Author(s):  
Zichria Zakay-Rones
Keyword(s):  
Influenza Vaccines ◽  
Human Influenza

A new sensitive radial diffusion method for microdetermination of α-amylase

1982 ◽  
Vol 120 (2) ◽  
pp. 262-266 ◽  
Author(s):  
Horst-Dietmar Tauschel ◽  
Claus Rudolph
Keyword(s):  
Radial Diffusion ◽  
Diffusion Method

Evaluation of the reversibility of iodide uptake by argillaceous rocks by the radial diffusion method

2006 ◽  
Vol 94 (9-11) ◽  
Author(s):  
S. Savoye ◽  
J.-L. Michelot ◽  
C. Wittebroodt
Keyword(s):  
Radial Diffusion ◽  
Diffusion Method ◽  
Iodide Uptake ◽  
Argillaceous Rocks

Laboratory radial in- and out-diffusion experiments were performed to investigate the reversibility of the iodide (I

scholarly journals A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface

mBio ◽  
2021 ◽  
Author(s):  
Kevin R. McCarthy ◽  
Jiwon Lee ◽  
Akiko Watanabe ◽  
Masayuki Kuraoka ◽  
Lindsey R. Robinson-McCarthy ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Herd Immunity ◽  
Influenza Viruses ◽  
Influenza Vaccines ◽  
Human Antibody ◽  
Human Influenza ◽  
Human Antibodies ◽  
Influenza Virus Hemagglutinin ◽  
Selection For ◽  
Rapid Appearance

The rapid appearance of mutations in circulating human influenza viruses and selection for escape from herd immunity require prediction of likely variants for an annual updating of influenza vaccines. The identification of human antibodies that recognize conserved surfaces on the influenza virus hemagglutinin (HA) has prompted efforts to design immunogens that might selectively elicit such antibodies.

scholarly journals Respiratory and intramuscular immunization with ChAdOx2 NPM1-NA induces distinct immune responses in H1N1pdm09 pre-exposed pigs

2021 ◽  
Author(s):  
Eleni Vatzia ◽  
Elizabeth Allen ◽  
Tanuja Manjegowda ◽  
Susan Morris ◽  
Adam McNee ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Responses ◽  
Protective Immunity ◽  
Matrix Protein ◽  
Antibody Responses ◽  
Influenza Vaccines ◽  
Human Influenza ◽  
Aerosol Delivery ◽  
Vectored Vaccine ◽  
The Impact

Abstract There is a critical need to develop superior influenza vaccines that provide broader protection. Influenza vaccines are traditionally tested in naïve animals, although humans are exposed to influenza in the first years of their lives, but the impact of prior influenza exposure on vaccine induced immune responses has not been well studied. Pigs are an important natural host for influenza, are a source of pandemic viruses, and are an excellent model for human influenza. Here we investigated the immunogenicity of the ChAdOx2 viral vectored vaccine, expressing influenza nucleoprotein, matrix protein 1 and neuraminidase in H1N1pdm09 pre-exposed pigs. We evaluated the importance of route of administration by comparing intra-nasal, aerosol and intra-muscular immunizations. Aerosol delivery boosted the local lung T cell and antibody responses, while intra-muscular immunization boosted systemic immunity. These results will inform how best to deliver vaccines in order to harness optimal protective immunity.

scholarly journals Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8+ T cells more relevant to current infections

2018 ◽  
Vol 14 (4) ◽  
pp. 941-946 ◽  
Author(s):  
D. Korenkov ◽  
T. H. O. Nguyen ◽  
I. Isakova-Sivak ◽  
T. Smolonogina ◽  
L. E. Brown ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Influenza Vaccines ◽  
Human Influenza
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