Basic fibroblast growth factor promotes transmitter storage and synthesis in cultured chromaffin cells

1992 ◽  
Vol 65 (2) ◽  
pp. 211-216 ◽  
Author(s):  
Klaus Unsicker ◽  
Reiner Westermann
1991 ◽  
Vol 33 (2) ◽  
pp. 212
Author(s):  
R. Westermann ◽  
D. Blottner ◽  
C. Grothe ◽  
K. Unsicker

1989 ◽  
Vol 37 (12) ◽  
pp. 1877-1883 ◽  
Author(s):  
C Grothe ◽  
K Unsicker

We studied the distribution of basic fibroblast growth factor (bFGF) immunoreactivity in bovine adrenal gland, ovary, and pituitary, using a polyclonal anti-bFGF antibody. In the adrenal gland, the inner layers of the capsule, the zona glomerulosa of the cortex, and the chromaffin cells of the adrenal medulla were intensely stained. In the ovary, follicular epithelial cells of growing follicles and granulosa cells of mature follicles showed strong bFGF-like immunoreactivity. Endocrine cells of the pituitary anterior and intermediate lobes displayed a positive immunoreaction. Blood vessels, including endothelial and smooth muscle cells, as well as stromal cells in all three organs studied, were not stained. This distribution pattern of bFGF immunoreactivity is only partially compatible with the established mitogenic role of this protein, and suggests a wider spectrum of bFGF functions.


2006 ◽  
Vol 68 (3) ◽  
pp. 248-250 ◽  
Author(s):  
Shuko OKADA ◽  
Takashi MASU ◽  
Takahiko TSUNODA ◽  
Ryuhei OKUYAMA ◽  
Setsuya AIBA

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