Normal repair of gamma radiation-induced single-strand and double-strand DNA breaks in retinoblastoma fibroblasts

Author(s):  
William G. Woods ◽  
Michelene Lopez ◽  
Susan L. Kalvonjian
2011 ◽  
Vol 138 (2) ◽  
pp. 616-623 ◽  
Author(s):  
S.W. Lim ◽  
K.N. Ting ◽  
T.D. Bradshaw ◽  
N.A. Zeenathul ◽  
C. Wiart ◽  
...  

Genetics ◽  
1996 ◽  
Vol 143 (3) ◽  
pp. 1115-1125 ◽  
Author(s):  
Fei Xu ◽  
Thomas D Petes

Abstract Meiotic recombination in Saccharomyces cerevisiae is initiated by double-strand DNA breaks (DSBs). Using two approaches, we mapped the position of DSBs associated with a recombination hotspot created by insertion of telomeric sequences into the region upstream of HIS4. We found that the breaks have no obvious sequence specificity and localize to a region of ~50 bp adjacent to the telomeric insertion. By mapping the breaks and by studies of the exonuclease III sensitivity of the broken ends, we conclude that most of the broken DNA molecules have blunt ends with 3′-hydroxyl groups.


2010 ◽  
Vol 32 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Anna Łękawa–Ilczuk ◽  
Halina Antosz ◽  
Beata Rymgayłło–Jankowska ◽  
Tomasz Żarnowski

2017 ◽  
Vol 23 (26) ◽  
pp. 6459-6459
Author(s):  
Sebastian Bestgen ◽  
Carmen Seidl ◽  
Thomas Wiesner ◽  
Andreas Zimmer ◽  
Martina Falk ◽  
...  

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