Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers

1992 ◽  
Vol 25 (1) ◽  
pp. 37-42 ◽  
Author(s):  
M.R.L. Stratford ◽  
A. Rojas ◽  
D.W. Hall ◽  
M.F. Dennis ◽  
S. Dische ◽  
...  
2018 ◽  
Vol 5 (3) ◽  
pp. 96-101
Author(s):  
I. M. Ordiyants ◽  
U. T. Mekhdieva ◽  
A. M. Savicheva

Purpose.The goal is to determine the real possibili es of assessing the fetal condi on in the ante- and intranatal periods according to the data of cardiotocography.Paents and methods.73 pa ents with physiological pregnancy at 24-40 weeks were prospec vely examined. The prac cal signifi cance of the g6b plus General MEDITECH automated fetal monitor, which allows to determine the condi on of the mother and fetus at the same  me, was evaluated.Results.The average blood pressure in the examined women was 127.2 ± 3.6 by 73.7 ± 2.3 mm. gt; pillars, pulse – 76 ± 1,5 beats/min. As for the contrac le capacity of the uterus, 47 (64,4%) pregnant women in 24–30 weeks. associated with diagnosis, and 19 (26%) – are harbingers of the forthcoming birth. The average SpO2was 99.12 ± 0.11%. Regardless of the gesta onal age, in 7 (9.6%) pregnant women – 97%, 40 (54.8%) – 99% and 21 (28.8%) – 100%. In order to assess the fetal condi on by the nature of his heartbeat, we performed an automated CTG analysis according to W. Fisher, D. Redman, FIGO: according to W. Fisher, depending on the gesta onal age of 6–7 points, 12 (16.4%) pregnant women in 25–26 weeks and 9 (12.3%) – 40 weeks, which according to the ball scale corresponds to a suspicious type. The Doze–Redman criteria were met in 47 (64.4%) pregnant women and were not met – in 26 (35.6%). Interpreta on according to FIGO guidelines as normal was detected in 64 (87.7%) pregnant women and in 9 (12.3%) – doub ul. Depending on the period of pregnancy, this group consisted of the same 9 (12.3%) pregnant women in a period of 40 weeks.Conclusion.Automated analysis allows for the correla on between the main indicators of the well-being of the maternal organism (SpO2, blood pressure, pulse, body temperature, ECG) and fetal CTG parameters (Fisher scale, Dowz Redman criteria and FIGO guidelines) to develop obstetric tac cs for each specifi c pa ent during pregnancy and childbirth.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Kazuhiro Tachibana ◽  
Noriyuki Ueki ◽  
Takuji Uchida ◽  
Hiroshi Koga

To compare the therapeutic efficacy of acupuncture, massage, and Tachibana-Ryojutsu (one of Japanese traditional body balance therapy techniques (SEITAI)), on stiff shoulders, the subjects’ muscle firmness, blood pressure, pulse, VAS, and body temperature were measured before and after the treatment. Forty-seven volunteer subjects gave written informed consent to participate in this study. The subjects were randomly divided into three groups to receive acupuncture, massage, or Tachibana-Ryojutsu. Each therapy lasted for 90 seconds. The acupuncture treatment was applied by a retaining-needle at GB-21, massage was conducted softly on the shoulders, and Tachibana-Ryojutsu treated only the muscles and joints from the legs to buttocks without touching the shoulders or backs. The study indicated that the muscle firmness and VAS of the Tachibana-Ryojutsu group decreased significantly in comparison with the acupuncture and massage groups after treatment.


2021 ◽  
Vol 2 (Issue 4) ◽  
pp. 1-8
Author(s):  
Joshua Juma Mugane

The analysis and discussion concerning death as intended by the Researcher depicts that death is an irreversible condition or state encountered by beings (all living creatures), due to a total dysfunction of the body organs. Such an irreversible condition is an enemy of human beings, which supersedes humanity, causing unexpected changes in life. It came as a punishment of abusing the supernatural power and finally it became a fact of not living forever. By the use of different literatures, Interviews and Documents, the research explored diverse concerns of death and drew its conclusion. Some of those concerns are “how is death detected? What are the causatives of death? Does death have its remedy? Where are dead people? Why do we bury the dead? And what is next after death?” The findings reveal that Doctors prove death by assessing and measuring the vital signs such as Blood Pressure, Pulse Rate, Respiratory Rate and Body Temperature. Moreover, the causatives of death include chronic pulmonary obstructive disease, ischemia, stroke, dehydration, infections and pain as well as old age. Those who encounter death are laid in the graves because God commanded it to be so and they produce unpleasant smell and stink. The remedy of it depends on the supernatural power that is believed to have ability of restoring the lost lives at consummation. That’s why Christians believe that on the second coming of Jesus Christ, all the dead shall rise. Hence, human beings have to be kin enough in lifetime, so that they may prolong a bit their lifespan through observance of health principles and guidelines.


1969 ◽  
Vol 21 (02) ◽  
pp. 287-293 ◽  
Author(s):  
I. S Menon ◽  
F. D Burke ◽  
P. A Smith ◽  
D. J Newell ◽  
H. A Dewar

SummaryThe prolonged effect in human volunteers of brief but moderately intense exercise in enhancing fibrinolytic activity has been used to test various parameters which might have been causatively associated with the change.HMMA, venous blood glucose, body temperature and diastolic blood pressure did not alter significantly at any time. The increase in pulse rate immediately after exercise did not correlate closely with the rise in fibrinolytic activity and disappeared much sooner.Plasma cortisol and systolic blood pressure had both fallen significantly 1 hr after exercise as compared to their preexercise levels, but there was no significant inverse relationship between these parameters and the changes in fibrinolytic activity.It is concluded that the parameters measured were unlikely to be responsible for the observed changes in fibrinolytic activity.


2019 ◽  
Vol 6 (2) ◽  
pp. 116
Author(s):  
Hikmatulloh Hikmatulloh ◽  
Ami Rahmawati ◽  
Dede Wintana ◽  
Diah Ayu Ambarsari

<p><em>Pregnancy is a natural process in a woman, pregnancy usually has a period of 9 months 1 week divided into 3 trimesters. The discussion of this study on pregnancy focused on determining the health of pregnant women with the help of data mining processing on classification methods, data processing is done by the iterative dichotomized three (ID3) algorithm, there are 14 parameters measured in processing the dataset including stages of pregnancy, nausea and vomiting , flatulence, heartburn, sensitivity to smell, vaginal blood, urination, urination, blood pressure, pulse, body temperature and dehydration, tightness in the uterus, odor of vaginal discharge, color of vaginal discharge , and the result parameter as the label. In its calculation algorithm, ID3 produces an accuracy of 80.33%. The application of the ID3 algorithm in diagnosing pregnancy health is expected to produce useful information, the results of this study are implemented in an Android-based mobile application.</em></p><p><em><strong>Keywords</strong></em><em>: </em><em>fregnancy, ID3, android.</em></p><p><em>Kehamilan adalah sebuah proses alamiah pada seorang perempuan, masa kehamilan biasanya memiliki rentang waktu 9 bulan 1 minggu yang dibagi menjadi 3 trimester. Pembahasan penelitian ini mengenai kehamilan yang difokuskan pada penentuan kesehatan pada ibu hamil dengan bantuan pengolahan data mining pada metode klasifikasi, pengolahan data dilakukan dengan algoritma iterative dichotomiser three (ID3), ada 14 parameter yang di ukur dalam pengolahan dataset, diantaranya tahapan kehamilan, mual dan muntah, perut kembung, nyeri ulu hati, senssitif terhadap bau, darah pada vagina, sakit buang air kecil, jumlah buang air kecil, tekanan darah, denyut nadi, suhu tubuh dan dehidrasi, kencang pada rahim, bau cairan dari vagina, warna cairan dari vagina, dan parameter hasil sebagi label. Dalam perhitungannya algoritma ID3 menghasilkan akurasi sebesar 80,33%. Penerapan algoritma ID3 dalam mendiagnosa kesehatan kehamilan ini diharapkan menghasilkan informasi yang bermanfaat, maka hasil penelitian ini di implementasikan dalam aplikasi mobile berbasis android.</em></p><strong><em>Kata kunci: </em></strong><em>kehamilan, ID3, android.<strong>   </strong></em>


Author(s):  
Tatsuya Yoshihara ◽  
Masayoshi Zaitsu ◽  
Kazuya Ito ◽  
Eunhee Chung ◽  
Mayumi Matsumoto ◽  
...  

Body temperature is important for diagnosing illnesses. However, its assessment is often a difficult task, considering the large individual differences. Although 37 °C has been the gold standard of body temperature for over a century, the temperature of modern people is reportedly decreasing year by year. However, a mean axillary temperature of 36.89 ± 0.34 °C reported in 1957 is still cited in Japan. To assess the measured axillary temperature appropriately, understanding its distribution in modern people is important. This study retrospectively analyzed 2454 axillary temperature measurement data of healthy Japanese adults in 2019 (age range, 20–79 years; 2258 males). Their mean temperature was 36.47 ± 0.28 °C (36.48 ± 0.27 °C in males and 36.35 ± 0.31 °C in females). Approximately 5% of the 20–39-year-old males had body temperature ≥37 °C, whereas 8% had a temperature ≥ 37 °C in the afternoon. However, none of the subjects aged ≥50 years reported body temperature ≥37 °C. In multivariable regression analysis, age, blood pressure, pulse rate, and measurement time of the day were associated with axillary temperature. Our data showed that the body temperature of modern Japanese adults was lower than that reported previously. When assessing body temperature, the age, blood pressure, pulse rate, and measurement time of the day should be considered.


Sign in / Sign up

Export Citation Format

Share Document