scholarly journals The nucleotide sequence of the peplomer gene of porcine transmissible gastroenteritis virus (TGEV): comparison with the sequence of the peplomer protein of feline infectious peritonitis virus (FIPV)

1987 ◽  
Vol 8 (4) ◽  
pp. 363-371 ◽  
Author(s):  
Liesbeth Jacobs ◽  
Raoul de Groot ◽  
Bernard A.M. van der Zeijst ◽  
Marian C. Horzinek ◽  
Willy Spaan
2008 ◽  
Vol 83 (3) ◽  
pp. 1532-1537 ◽  
Author(s):  
Nicola Decaro ◽  
Viviana Mari ◽  
Marco Campolo ◽  
Alessio Lorusso ◽  
Michele Camero ◽  
...  

ABSTRACT Four canine coronavirus type II (CCoV-II) strains were identified in the guts and internal organs of pups which had died of acute gastroenteritis. The CCoV-II strains were strictly related to porcine transmissible gastroenteritis virus (TGEV) in the N-terminal domain of the spike protein, whereas in the other parts of the genome, a higher genetic relatedness to recent CCoV-II isolates was observed. Experimental infection of dogs with a TGEV-like isolate induced mild gastroenteritis without any systemic involvement. By virus neutralization tests, antigenic differences between reference and TGEV-like CCoVs were found. Our data support the potential recombinant origin of the TGEV-like CCoVs.


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